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Progress in Research on Microplastics and Nano-plastics Cardiac Toxicity
Summary
This review covers experimental and clinical evidence on the cardiovascular toxicity of microplastics and nanoplastics, documenting effects on heart function, vascular integrity, and inflammation pathways. It calls for more human clinical data to clarify the dose-response relationship and the relevance of laboratory findings to real-world cardiac risk.
In recent years, research on the biological toxicity of microplastics and nano-plastics has emerged in the medical field, especially with rapid progress in studies related to cardiovascular diseases. However, it should be objectively noted that the amount of clinical data from international research remains limited, while domestic research in related fields with access to clinical data sources is extremely scarce, and in-depth clinical investigations and research advances are urgently needed. This review summarizes the progress of studies on the cardiovascular toxicity of microplastics. Based on domestic and international basic research and the factually limited clinical research, it elaborates on the mechanisms of cardiovascular toxicity induced by microplastics, their biomarkers, and detection methods. Emphasis is placed on detection methods for direct evidence of biological origin and biomarkers, aiming to provide a reference for subsequent data collection in clinical research stages.