Papers

20 results
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Commentary Tier 3

Editorial: Probiotics for global health: advances, applications and challenges

This editorial synthesizes recent advances in probiotic research for global health applications, highlighting their potential to support host health, prevent disease, and counteract dysbiosis, while identifying key challenges in making safe and sustainable probiotic interventions more accessible.

2025 IMAGINE - Repository of the Institute of molecular genetics and genetic engineering (University of Belgrade)
Commentary Tier 3

Editorial: Probiotics for global health: advances, applications and challenges

This editorial review summarizes recent advances in probiotic research, covering their health benefits, applications in disease prevention, and challenges in scaling safe and effective probiotic interventions. The piece highlights probiotics as a promising complement to conventional therapies given the global burden of dysbiosis-related diseases.

2025 Frontiers in Microbiology 2 citations
Commentary Tier 3

Editorial: Impact of gut ecosystem in health and diseases: microbiome, mucosal barrier and cytokine milieu

This editorial introduces a research collection examining the gut ecosystem's role in health and disease, focusing on how the perinatal and lifetime 'exposome' (diet, pre/probiotics, environmental factors) shapes microbiome composition, mucosal barrier function, and cytokine/chemokine signaling in intestinal immunity.

2024 Frontiers in Microbiology
Article Tier 2

Microbiome First Approaches to Rescue Public Health and Reduce Human Suffering

This review advocates for Microbiome First public health approaches to address the failure of conventional disease prevention programs, arguing that restoring healthy microbiome diversity through diet, reduced antibiotic use, and reduced exposure to disruptors including microplastics and PFAS could reduce noncommunicable disease burden.

2021 Biomedicines 14 citations
Article Tier 2

The urgent need for microbiology literacy in society

This paper argues that society urgently needs better microbiology literacy to make informed decisions about issues ranging from public health to environmental management. Researchers highlight that microbes underpin critical functions in ecosystems, human health, and the biosphere, yet public understanding of microbiology remains extremely limited. The study calls for integrating microbiology education into broader scientific literacy efforts to help individuals and policymakers make better evidence-based decisions.

2019 Environmental Microbiology 177 citations
Article Tier 2

Improving the assessment of ecosystem and wildlife health: microbiome as an early indicator

Researchers reviewed evidence that the microbiome — the community of microorganisms living in environments and within animals — can serve as an early warning system for ecosystem disturbance, rapidly reflecting the impact of human activities before other signs of harm are visible.

2023 Current Opinion in Biotechnology 45 citations
Commentary Tier 3

Editorial: Microbial Ecotoxicology Advances to Improve Environmental and Human Health Under Global Change

This editorial introduces a special journal issue on microbial ecotoxicology, highlighting how microorganisms are affected by environmental contaminants including microplastics, pharmaceuticals, and other emerging pollutants. Understanding microbial responses to pollution is critical for assessing broader ecosystem and human health risks.

2022 Frontiers in Microbiology 4 citations
Article Tier 2

Polybiome Systems Medicine: Conceptual Architecture, Methodological Foundations, and Translational Applications — Volume I: Vision and Foundational Methodology

This foundational document presents the Polybiome Systems Medicine framework, proposing that the human organism is a co-constructed biological consortium shaped by host genomics, multi-kingdom microbiomes, environmental exposures, and immune networks. The framework incorporates environmental factors including microplastics and endocrine disruptors as modulators of human health. The authors outline a five-layer architecture designed to integrate diverse biological data for a more holistic approach to medicine.

2026 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

The plant microbiota signature of the Anthropocene as a challenge for microbiome research

Researchers argue that human activities during the Anthropocene — the current era of profound human influence on Earth — have fundamentally altered plant-associated microbial communities in ways that threaten ecosystem function and planetary health. Holistic studies are needed to understand and reverse this loss of microbial diversity.

2022 Microbiome 90 citations
Article Tier 2

Polybiome Systems Medicine: Conceptual Architecture, Methodological Foundations, and Translational Applications — Volume I: Vision and Foundational Methodology

This white paper introduces a theoretical framework called Polybiome Systems Medicine, which views the human body as a complex biological consortium shaped by genomic, microbial, environmental, and immune interactions. The framework includes environmental exposomes such as microplastics and endocrine disruptors as key factors influencing human health. The authors propose a five-layer systems architecture for integrating these diverse biological and environmental inputs into a unified medical model.

2026 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

The Human Archaeome: Commensals, Opportunists, or Emerging Pathogens?

This review examines the human archaeome—archaeal microorganisms inhabiting the gut, skin, and other body sites—and their potential roles in health and disease. It finds no conclusive archaeal pathogens in humans but identifies indirect roles through metabolic interactions with bacteria, relevant to gut microbiome research.

2025 Preprints.org
Commentary Tier 3

Editorial: Expert opinions: save the microbes to save the planet

This editorial discusses the role of microbes in planetary health, arguing that microbial communities are critical to addressing climate change, biodiversity loss, and environmental pollution including plastic degradation. The piece calls for greater scientific attention to protecting and harnessing microbial diversity as a tool for ecological restoration.

2025 Frontiers in Microbiology
Article Tier 2

Research trend on the emerging role of the microbiome in idiopathic male infertility

A bibliometric analysis of global research on idiopathic male infertility over two decades found a clear transition from genetic and oxidative stress approaches toward microbiome-centered and multi-omics investigations, reflecting growing interest in the gut-reproductive axis.

2025 Antonie van Leeuwenhoek
Article Tier 2

The concept of balance in microbiome research

This essay critically examines how the concept of "balance" is used in microbiome research and medical literature. Researchers analyzed multiple interpretations of what a balanced versus imbalanced microbiome means, finding that the term is often used loosely without precise scientific definition. The study argues for more rigorous conceptual frameworks to better understand how microbiome composition relates to health outcomes.

2024 BioEssays 2 citations
Article Tier 2

Microplastics and microbiota: Unraveling the hidden environmental challenge

This editorial summarizes the emerging evidence that microplastics disrupt the gut microbiome, decreasing microbial diversity and triggering an imbalance called dysbiosis. This disruption affects immune function, nutrient metabolism, and overall health, though the full long-term consequences of this two-way relationship between microplastics and gut bacteria remain an active area of research.

2024 World Journal of Gastroenterology 23 citations
Article Tier 2

Harnessing soil biodiversity to promote human health in cities

Researchers argue that urban soil biodiversity — the vast community of microorganisms, fungi, and invertebrates living in city soils — plays an overlooked role in human health by suppressing pathogens, shaping the human microbiome, and supporting immune function, and that restoring it in cities could offer meaningful public health benefits.

2023 npj Urban Sustainability 57 citations
Article Tier 2

Bibliometric Studies and Worldwide Research Trends on Global Health.

This editorial introduces a special issue addressing global health challenges including environmental problems like climate change and plastic pollution from a bibliometric perspective. The papers in the collection analyze research trends across environmental, disease, and health domains at a global scale.

2020 International journal of environmental research and public health
Article Tier 2

Planetary Health: Safeguarding Human Health and the Environment in the Anthropocene

This book on Planetary Health framed environmental degradation as a direct threat to human health across domains from pandemics to chronic disease to mental health, arguing that transformative changes in energy, food, housing, and transport systems are needed to simultaneously improve health outcomes and protect the natural systems on which human civilization depends.

2021 12 citations
Article Tier 2

Artificial intelligence, evolution, and environmental disease: Rethinking the risk

This editorial explores the potential risks of applying artificial intelligence to environmental disease research, arguing that without careful oversight, AI could introduce biases or overlook ecological complexity. The authors use Genome Architecture Theory as a framework for understanding how organisms interact with environmental factors, including pollutants like microplastics. The study urges the environmental health community to engage proactively in shaping how AI tools are developed and applied to ensure scientific integrity and equity.

2025 Environmental Disease 1 citations
Article Tier 2

Distinctive signatures of pathogenic and antibiotic resistant potentials in the hadal microbiome

Researchers mapped antibiotic resistance genes and disease-causing microbial traits in the deepest parts of the ocean — the Mariana Trench — revealing a unique and largely unknown landscape of microbial risk factors even in Earth's most remote environments.

2022 Environmental Microbiome 29 citations