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Distinctive signatures of pathogenic and antibiotic resistant potentials in the hadal microbiome
Summary
Researchers mapped antibiotic resistance genes and disease-causing microbial traits in the deepest parts of the ocean — the Mariana Trench — revealing a unique and largely unknown landscape of microbial risk factors even in Earth's most remote environments.
This study reports the landscape of virulence factors, antibiotic resistome, and mobilome in the sediment and seawater microbiota residing hadal environment of the deepest ocean bottom on earth. Our work unravels the contrasting and unique features of virulence genes, ARGs, and MGEs in the Mariana Trench bottom, providing new insights into the eco-environmental and biological processes underlying microbial pathogenicity, resistance, and adaptative evolution in the hadal environment.
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