We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Microbiome First Approaches to Rescue Public Health and Reduce Human Suffering
AI summary Read the abstract
This review advocates for Microbiome First public health approaches to address the failure of conventional disease prevention programs, arguing that restoring healthy microbiome diversity through diet, reduced antibiotic use, and reduced exposure to disruptors including microplastics and PFAS could reduce noncommunicable disease burden.
The is a sequential article to an initial review suggesting that Microbiome First medical approaches to human health and wellness could both aid the fight against noncommunicable diseases and conditions (NCDs) and help to usher in sustainable healthcare. This current review article specifically focuses on public health programs and initiatives and what has been termed by medical journals as a catastrophic record of recent failures. Included in the review is a discussion of the four priority behavioral modifications (food choices, cessation of two drugs of abuse, and exercise) advocated by the World Health Organization as the way to stop the ongoing NCD epidemic. The lack of public health focus on the majority of cells and genes in the human superorganism, the microbiome, is highlighted as is the "regulatory gap" failure to protect humans, particularly the young, from a series of mass population toxic exposures (e.g., asbestos, trichloroethylene, dioxin, polychlorinated biphenyls, triclosan, bisphenol A and other plasticizers, polyfluorinated compounds, herbicides, food emulsifiers, high fructose corn syrup, certain nanoparticles, endocrine disruptors, and obesogens). The combination of early life toxicity for the microbiome and connected human physiological systems (e.g., immune, neurological), plus a lack of attention to the importance of microbial rebiosis has facilitated rather than suppressed, the NCD epidemic. This review article concludes with a call to place the microbiome first and foremost in public health initiatives as a way to both rescue public health effectiveness and reduce the human suffering connected to comorbid NCDs.
More Papers Like This
Microplastic emerging pollutants – impact on microbiological diversity, diarrhea, antibiotic resistance, and bioremediation
AI summary Read the abstract
This review examines how global plastic waste accumulation affects microbial diversity, promotes diarrheal disease, and accelerates antibiotic resistance, while also surveying bioremediation strategies for managing microplastic pollution.
Impact of microplastics on human health: A critical role of gut microbiota
AI summary Read the abstract
Researchers systematically reviewed how microplastics traverse biological barriers and deposit in human organs, documenting that ingested MPs mechanically damage the intestinal lining, shift gut microbiota toward a Firmicutes-dominant profile, and disrupt metabolite production — changes that propagate via gut-liver and gut-brain axes to contribute to metabolic, cardiovascular, neurological, and reproductive disorders, positioning microbiome modulation as a potential therapeutic strategy.
Microplastics—The Microbiota Interactions: Mechanisms, Multi-Omics Insights and Health Implications
AI summary Read the abstract
Researchers reviewed how microplastics interact with microbial communities across terrestrial, aquatic, and gut environments, synthesizing evidence from in vitro, in vivo, and environmental studies showing that MP exposure drives dysbiosis, impairs immune function, and accelerates the spread of antibiotic resistance genes.
Symbiotoxicity: The Ability of Environmental Stressors to Damage Healthy Microbiome Structure and Interactions with the Host
AI summary Read the abstract
This review proposes the concept of symbiotoxicity to describe how environmental stressors including microplastics, chemicals, and pathogens can disrupt healthy host-microbiome interactions, arguing that damage to the microbiome should be considered a distinct endpoint in ecological risk assessment.
Role of Microbes in Microplastic Removal and Its Effect on Human Health
AI summary Read the abstract
This review examines the role of microbes in microplastic removal from environmental matrices and food systems, covering both degradation pathways and the health implications of microplastic-microbiome interactions for humans and other organisms.
Research digests by email
When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.