Papers

61,005 results
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Article Tier 2

Immunological and Genotoxic Effects of Polystyrene Microparticles on the Model Insect Tenebrio molitor L. (Coleoptera: Tenebrionidae)

Researchers fed mealworm (Tenebrio molitor) larvae polystyrene microplastics at four dose levels and assessed immune function and DNA damage. Dietary exposure caused dose-dependent increases in larval mortality, immune cell changes, and genotoxic damage, indicating that even insect species used in waste degradation studies are harmed by microplastic ingestion.

2025 Transactions of the American Entomological Society
Article Tier 2

Toxic effects of acute exposure to polystyrene microplastics and nanoplastics on the model insect, silkworm Bombyx mori

Researchers tested the effects of polystyrene microplastics and nanoplastics on silkworms and found that while the particles did not affect body weight or survival, they significantly altered immune gene activity and antioxidant responses. Interestingly, microplastics boosted immune defenses while nanoplastics suppressed them, meaning silkworms exposed to nanoplastics were more vulnerable to bacterial infection. The study suggests that plastic particle size is a critical factor in determining the nature and severity of toxic effects on organisms.

2021 Environmental Pollution 119 citations
Article Tier 2

Ingestion and effects of polystyrene nanoparticles in the silkworm Bombyx mori

Scientists fed polystyrene nanoparticles to silkworm larvae (Bombyx mori) and found ingestion, tissue accumulation, and oxidative stress responses, demonstrating that terrestrial insects are vulnerable to nanoplastic exposure through their food.

2020 Chemosphere 69 citations
Article Tier 2

Ingestion of polystyrene microparticles impairs survival and defecation in larvae of Polistes satan (Hymenoptera: Vespidae)

Researchers found that polystyrene microplastic ingestion significantly impaired survival and defecation in larvae of the paper wasp Polistes satan, with effects dependent on particle size and concentration. The findings demonstrate that terrestrial insects are vulnerable to microplastic contamination and that ingestion can disrupt basic physiological functions.

2023 1 citations
Article Tier 2

Ingestion of polystyrene microparticles impairs survival and defecation in larvae of Polistes satan (Hymenoptera: Vespidae)

Researchers found that ingestion of polystyrene microparticles impaired survival and defecation in paper wasp larvae, with higher doses causing greater mortality, demonstrating that terrestrial insects are vulnerable to microplastic contamination.

2023 Environmental Science and Pollution Research 8 citations
Article Tier 2

Influence of nano-polystyrene on cyfluthrin toxicity in honeybee Apis cerana cerana Fabricius

Researchers found that nano-polystyrene plastics damaged the gut and gland development of Asian honeybees, while also changing how the bees process toxins at the genetic level. When combined with the pesticide cyfluthrin, the nanoplastics altered detoxification and immune gene activity in complex ways. Since honeybees are essential pollinators for food crops, the toxic effects of nanoplastics on bee health could have indirect consequences for human food security.

2025 Ecotoxicology and Environmental Safety 8 citations
Article Tier 2

Nano- and micro-polystyrene plastics disturb gut microbiota and intestinal immune system in honeybee.

Honeybees orally exposed to polystyrene micro- and nanoplastics showed disrupted gut microbiota and impaired intestinal immune function, with nanoplastics causing greater effects than microplastics. Since honeybees are critical pollinators for food production, microplastic contamination in their environment could affect both bee health and agricultural systems.

2022 The Science of the total environment
Article Tier 2

Enhanced bioaccumulation and toxicity of Fenpropathrin by polystyrene nano(micro)plastics in the model insect, silkworm (Bombyx mori)

Researchers found that polystyrene nano- and microplastics made the pesticide fenpropathrin more toxic to silkworms by acting as carriers that increased the insect's absorption of the chemical. The smaller the plastic particles were, the more they boosted pesticide accumulation in the silkworms' bodies, raising concerns about how microplastics may amplify the effects of other environmental toxins.

2025 Journal of Nanobiotechnology 15 citations
Article Tier 2

Hazard assessment of ingested polystyrene nanoplastics in Drosophila larvae

Researchers assessed the hazard of ingested polystyrene nanoplastics in Drosophila larvae, examining effects on gut morphology, oxidative stress, and development to characterize toxicological risks of nanoplastic exposure in a model invertebrate organism.

2022 Environmental Science Nano 39 citations
Systematic Review Tier 1

Interactions of insects with micro- and nanoplastics: A review

This comprehensive review of 114 studies found that micro- and nanoplastics accumulate in both terrestrial and aquatic insects, causing reduced growth, impaired reproduction, oxidative stress, and gut microbiome disruption. Since insects are foundational to food webs and pollination, plastic contamination in insect populations could cascade through ecosystems and ultimately affect human food systems.

2026 The Science of The Total Environment
Article Tier 2

Molecular mechanisms of nano-sized polystyrene plastics induced cytotoxicity and immunotoxicity in Eisenia fetida

Researchers studied how polystyrene nanoplastics affect earthworm immune cells and found that exposure caused significant oxidative stress, DNA damage, and weakened immune function. The nanoplastics physically bound to and damaged lysozyme, a key immune protein, impairing the earthworms' ability to fight off infections. Since earthworms are essential soil organisms, this immune damage could have cascading effects on soil health and the agricultural systems that humans depend on.

2023 Journal of Hazardous Materials 39 citations
Article Tier 2

Impact of Polystyrene Micro- and Nanoplastics on the Biological Traits of the Japanese Carpenter Ant, Camponotus japonicus Mayr (Hymenoptera: Formicidae)

Researchers exposed Japanese carpenter ants to polystyrene micro and nanoplastics of different sizes and found that exposure changed their foraging behavior, reduced food intake, and affected survival rates. Smaller nanoplastics caused more severe effects than larger microplastics, consistent with findings in other organisms. While this study focused on insects, it adds to growing evidence that nanoplastics are more biologically harmful than larger particles across many species.

2025 Insects 7 citations
Article Tier 2

Amino-modified polystyrene nanoplastics induced multiple response of Artemia hemocytes

Researchers exposed the zooplankton Artemia to amino-modified polystyrene nanoplastics and observed multiple adverse responses in their blood cell system. The nanoplastics triggered changes across five hemocyte subpopulations, causing cell death, oxidative stress, and altered immune function at environmentally relevant concentrations. The study suggests that nanoplastic pollution may compromise the innate immune defenses of small aquatic organisms at the base of the food chain.

2024 Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology 3 citations
Article Tier 2

Exposure to polystyrene nanoparticles at predicted environmental concentrations enhances toxic effects of Acinetobacter johnsonii AC15 infection on Caenorhabditis elegans

Researchers found that exposure to polystyrene nanoparticles at low, environmentally realistic concentrations made a bacterial infection significantly more harmful to the roundworm C. elegans. The nanoparticles increased bacterial accumulation in the worms' bodies and weakened their innate immune responses. The study suggests that nanoplastic pollution in the environment could amplify the toxicity of common microbial pathogens.

2023 Ecotoxicology and Environmental Safety 24 citations
Article Tier 2

Toxicological impacts of microplastics on virulence, reproduction and physiological process of entomopathogenic nematodes

This study found that polystyrene microplastics are toxic to beneficial soil nematodes that naturally control insect pests in agriculture. The microplastics reduced the nematodes' survival, reproduction, and ability to kill pest insects, with smaller particles and higher concentrations causing the most damage. This matters because losing these natural pest controllers could lead to increased pesticide use, creating a cycle of more chemical contamination in the soil and food supply.

2024 Ecotoxicology and Environmental Safety 12 citations
Article Tier 2

Polystyrene Nanoplastics Elicit Multiple Responses in Immune Cells of the Eisenia fetida (Savigny, 1826)

This study examined how nanoplastics from polystyrene affect the immune cells of earthworms, which play a critical role in soil ecosystems. Researchers found that the tiny plastic particles were taken up by the cells, triggered oxidative stress, weakened antioxidant defenses, destabilized cell membranes, and initiated early-stage cell death. The results provide cellular-level evidence that nanoplastic exposure poses ecological risks to soil-dwelling organisms.

2024 Toxics 6 citations
Article Tier 2

A potential enzymatic pathway for polystyrene degradation using saliva of greater wax moth Galleria mellonella

Researchers investigated whether saliva from the greater wax moth Galleria mellonella larvae contains enzymes capable of degrading polystyrene, identifying a potential enzymatic pathway that could offer a biodegradation route for this highly persistent synthetic polymer.

2025 Journal of Emerging Investigators
Article Tier 2

Genotoxic and immunomodulatory effects in human white blood cells after ex vivo exposure to polystyrene nanoplastics

Human white blood cells were exposed ex vivo to polystyrene nanoplastics and showed DNA strand breaks, chromosomal damage, and changes in immune cell activation markers, suggesting that nanoplastics at environmentally relevant concentrations could cause genotoxic and immunomodulatory effects in people.

2020 Environmental Science Nano 68 citations
Article Tier 2

Polystyrene nanoplastics differentially influence the outcome of infection by two microparasites of the host Daphnia magna

Researchers exposed the water flea Daphnia magna to two different parasites in the presence of polystyrene nanoplastics. The study found that nanoplastic exposure dramatically increased infection rates by a fungal parasite while having no significant effect on a gut microsporidium, suggesting that nanoplastics can differentially affect host-parasite relationships and potentially favor parasite coexistence in aquatic environments.

2023 Philosophical Transactions of the Royal Society B Biological Sciences 15 citations
Article Tier 2

Polystyrene microplastics alter physiological parameters in the Drosophila model

Researchers investigated the effects of polystyrene micro- and nanoplastics on fruit flies (Drosophila melanogaster) and found dose- and size-dependent toxicity at both larval and adult stages. Exposure caused significant behavioral impairments, elevated markers of cellular stress, and activated key stress response genes, indicating that polystyrene microplastics induce oxidative stress and cellular damage.

2026 Environmental Science and Pollution Research
Article Tier 2

Complete digestion/biodegradation of polystyrene microplastics by greater wax moth (Galleria mellonella) larvae: Direct in vivo evidence, gut microbiota independence, and potential metabolic pathways

Researchers provided direct in vivo evidence that greater wax moth larvae can completely digest polystyrene microplastics, demonstrating that biodegradation occurs independently of gut microbiota and identifying potential metabolic pathways involved in the breakdown process.

2021 Journal of Hazardous Materials 113 citations
Article Tier 2

Cellular Uptake and Tissue Retention of Microplastics in Black Soldier Fly Larvae

Researchers found that polystyrene microplastics injected into black soldier fly larvae persisted in tissues for up to seven days, with hemocytes actively phagocytosing particles and microplastics accumulating in metabolically active organs including the fat body and Malpighian tubules.

2025 Insects
Meta Analysis Tier 1

A global meta-analysis reveals the toxicity of plastics on insect health

This meta-analysis pools data from global studies to reveal that microplastics and nanoplastics are harmful to insect health, affecting survival, reproduction, and development. Since insects play critical roles in pollination and food chains, their decline from plastic pollution could have cascading effects on agriculture and the broader ecosystems humans depend on.

2025 Ecotoxicology and Environmental Safety 5 citations
Article Tier 2

Multigenerational growth inhibition and oxidative stress of polystyrene micro(nano)plastics on earthworms (Eisenia fetida)

Researchers exposed earthworms to polystyrene nano- and microplastics across two generations, finding both particle types reduced offspring numbers by 23–39%, disrupted reproductive tissue structure, and caused oxidative stress, with nanoplastics producing more severe multigenerational effects.

2025 Environmental Research