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Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Environmental Sources Human Health Effects Nanoplastics Sign in to save

Genotoxic and immunomodulatory effects in human white blood cells after ex vivo exposure to polystyrene nanoplastics

Environmental Science Nano 2020 68 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Sandra Ballesteros, Josefa Domenech, Irene Barguilla, Constanza Cortés, Ricard Marcos, Alba Hernández

Summary

Human white blood cells were exposed ex vivo to polystyrene nanoplastics and showed DNA strand breaks, chromosomal damage, and changes in immune cell activation markers, suggesting that nanoplastics at environmentally relevant concentrations could cause genotoxic and immunomodulatory effects in people.

Polymers

Accumulation of plastic and its derivatives, micro- and nanoplastics (MNPLs), is a substantial environmental and ecological problem that could potentially become a serious health concern to humans.

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