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61,005 resultsShowing papers similar to Microplastic Contamination: A Rising Environmental Crisis With Potential Oncogenic Implications
ClearFrom Exposure to Oncogenesis: the Role of Microplastics and Associated Pollutants in Cancer - a Literature Review
This literature review examined the growing evidence linking microplastic exposure to cancer development. Microplastics have been found in human lung, liver, and colon tissue, and research suggests they may promote cancer through chronic inflammation, oxidative stress, and by carrying known carcinogens like heavy metals and persistent organic pollutants into the body.
Microplastics and cancer
This review examines evidence linking microplastics to cancer risk, noting that microplastics have been detected at higher concentrations in human tumor tissues than adjacent healthy tissue, and that they can act as vectors for carcinogens while inducing oxidative stress, inflammation, and genotoxicity.
Microplastics as emerging carcinogens: from environmental pollutants to oncogenic drivers
This review examines growing evidence that microplastics and nanoplastics may play a role in cancer development, with these particles found in human tumor tissues from the lungs, colon, stomach, breast, and other organs. The particles appear to promote cancer through chronic inflammation, oxidative stress, DNA damage, and disruption of key cancer-related signaling pathways. While direct proof of causation in humans is still lacking, the accumulating evidence from lab studies, animal experiments, and human tissue analysis suggests microplastics deserve serious attention as potential contributors to cancer risk.
From exposure to oncogenesis: a review on the multifaceted roles of microplastics in tumor initiation and progression
This review examined the evidence linking microplastic exposure to tumor initiation and progression, covering physical, chemical, and inflammatory mechanisms by which MPs may promote oncogenesis. The authors conclude that while current evidence is largely preclinical, accumulating data warrant serious concern about microplastics as environmental carcinogens.
Microscopic menace: exploring the link between microplastics and cancer pathogenesis
This review examines the growing evidence linking microplastic exposure to cancer development in humans. Microplastics can accumulate in the body and trigger inflammation, oxidative stress, and other biological changes associated with tumor growth. While more clinical research is needed, the review highlights that microplastics should be taken seriously as a potential factor in cancer risk.
Micro(nano)plastics pollution and human health: How plastics can induce carcinogenesis to humans?
This review examines how microplastics and nanoplastics enter the human body through food, water, and air, and how they may contribute to cancer development. Common plastic types like polystyrene and PVC, along with toxic chemicals they carry such as PAHs and PCBs, have been linked to DNA damage, oxidative stress, and inflammation, all of which can promote cancer. The paper highlights that while the evidence is growing, more research is needed to understand the full cancer risk from chronic microplastic exposure.
Evaluating the relationship between microplastics and nanoplastics contamination and diverse cancer types development
This review examines growing evidence that micro- and nanoplastics found in human tissues may contribute to cancer development through several pathways. These tiny particles can generate harmful molecules called reactive oxygen species, cause chronic inflammation, and disrupt cell growth signals, all of which are known to promote cancer. While long-term, high-level exposure likely poses the greatest risk, more research is needed to understand the full cancer-related dangers of microplastic exposure.
Micro(Nano)Plastics as Carriers of Toxic Agents and Their Impact on Human Health
This review compiles evidence on how micro- and nanoplastics act as carriers of potentially toxic agents and enter the human body through inhalation, ingestion, and dermal absorption. Evidence indicates that continuous exposure to these particles can lead to bioaccumulation and negative health alterations, with recent research detecting microplastics even in human placental tissue.
The alarming link between environmental microplastics and health hazards with special emphasis on cancer
This review describes how microplastics enter the human body through the nose, skin, and mouth, then penetrate cells where they can alter gene expression, fuel inflammation, disrupt hormone signaling, and promote uncontrolled cell growth. Studies have linked microplastic exposure to cancers of the lungs, blood, breast, prostate, and ovaries, though the precise molecular mechanisms still need further investigation.
The Relationship Between Microplastics and Nanoplastics with Cancer: An Emerging Health Concern
This review explores the emerging relationship between micro- and nanoplastic exposure and cancer risk in humans. Researchers summarized evidence suggesting that microplastics can carry carcinogenic substances and may trigger inflammatory and oxidative stress pathways linked to tumor development. The study highlights that while early evidence raises concern, more research is needed to establish clear causal connections between plastic particle exposure and specific cancer types.
Micro(nano)plastics: Unignorable vectors for organisms
This review examines the role of micro- and nanoplastics as vectors for contaminants — including heavy metals, organic pollutants, and pathogens — in aquatic and terrestrial environments. It synthesizes evidence on how plastic particles can adsorb, transport, and release harmful substances, amplifying their ecological and health risks beyond the physical effects of the particles alone.
Micro(nano)plastics, an emerging health problem
This review frames micro- and nanoplastics as an emerging human health problem, synthesizing evidence of exposure routes, organ-level accumulation, and biological effects, and calling for updated regulatory frameworks to address this novel class of environmental contaminants.
Plastic pollution-Microplastics: Cancer related issues
This review examines how microplastics may contribute to cancer risk, summarizing evidence that ingested microplastics can cross the gut epithelium, accumulate in tissues, induce oxidative stress and inflammation, and carry carcinogenic chemical additives.
Rising Concern About the Carcinogenetic Role of Micro-Nanoplastics
This review examined the emerging concern that micro- and nanoplastics may play a role in cancer development, either directly or by carrying chemical carcinogens into the body. Researchers noted that while direct evidence is still limited, the rising incidence of certain cancers in younger populations alongside increasing environmental plastic contamination has raised important questions. The study calls for more focused research to understand whether long-term microplastic exposure may contribute to cancer risk and what preventive measures might be warranted.
Microplastics as vectors of environmental contaminants: Interactions in the natural ecosystems
This review examines how microplastics act as vectors for pathogens, persistent organic pollutants, and heavy metals in marine, freshwater, and terrestrial ecosystems, summarising evidence that these particles damage cell membranes, tissues, and physiological processes in exposed organisms.
The impact of environmental microplastics as emerging carcinogens: A public health concern
This review investigated the mechanisms by which microplastics may contribute to cancer development, examining studies from 2010 to 2024. Researchers found that microplastics can induce oxidative stress, inflammation, and DNA damage through multiple pathways, and that human exposure occurs primarily through ingestion, inhalation, and dermal contact. The study suggests that microplastics represent an emerging class of environmental concern warranting further investigation into their long-term health effects.
Micro and nano-plastics, a threat to human health?
This review examines the threat micro- and nanoplastics pose to human health, discussing how these persistent particles accumulate in organs including lungs, the gastrointestinal system, and blood, and how their chemical composition and size influence toxicity.
Research progress on environmental occurrence of microplastics and their interaction mechanism with organic pollutants
This review summarizes how microplastics in the environment interact with organic pollutants—adsorbing, carrying, and releasing them. Microplastics act as mobile carriers for persistent organic chemicals, altering their distribution and toxicity in ecosystems and the organisms, including humans, that consume them.
Microplastics – A Growing Concern as Carcinogens in Cancer Etiology: Emphasis on Biochemical and Molecular Mechanisms
This review describes how microplastics smaller than 5 mm can enter human cells and promote cancer development through multiple pathways, including DNA damage, oxidative stress, chronic inflammation, and disruption of cell growth controls. Microplastics also carry other contaminants into the body, and their accumulation in tissues raises concerns about long-term cancer risk, particularly in the lungs, skin, and digestive system.
Rising Concern About the Carcinogenetic Role of Micro‐Nanoplastics
This review raised concerns about the carcinogenic potential of micro- and nanoplastics, synthesizing evidence that these particles can induce DNA damage, oxidative stress, and cellular transformation. It called for accelerated research into whether microplastic exposure increases human cancer risk.
The hidden threat: Microplastics and cancer biology
This review synthesizes current research on the potential links between micro- and nanoplastic exposure and cancer biology, examining how these particles may contribute to tumor development in organs including the gut, lungs, skin, liver, kidney, and brain. The study suggests that chronic exposure to plastic particles can trigger molecular changes such as oxidative stress, inflammation, and DNA damage that are associated with cancer initiation, though clear causal evidence in humans is still lacking.
Microplastics in Human Tissues: Sources, Distribution, Toxicological Effects, and Health Implications
Researchers reviewed the growing body of evidence that microplastics accumulate in human tissues — including lung, blood, placenta, breast milk, and heart tissue — where they can trigger inflammation, oxidative stress, and cell death. The review highlights urgent knowledge gaps around how plastic particles move through the body and what their long-term health effects may be.
Insights into the potential carcinogenicity of micro- and nano-plastics.
This review examined existing evidence on the carcinogenic potential of micro- and nano-plastics, finding studies demonstrating genotoxicity, oxidative DNA damage, disruption of cell signaling, and tumor-promoting effects, while noting that direct human carcinogenicity data remain limited and mechanistic pathways require further investigation.
Microplastics in the Human Food Chain: Exposure and Health Implications
This review documents how microplastics have permeated the human food chain and are now detected in human tissues including lungs, liver, placenta, and breast milk, examining exposure routes through ingestion, inhalation, and dermal contact and the potential health consequences of this ubiquitous contamination.