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Microplastic Contamination: A Rising Environmental Crisis With Potential Oncogenic Implications

Cureus 2025 Score: 48 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Muhammad Imran

Summary

This review examines how microplastics detected in human tissues — blood, placenta, and organs — may act as vectors for carcinogens, including adsorbed heavy metals and persistent organic pollutants, and discusses emerging evidence linking MP accumulation to oncogenic processes.

Microplastics have emerged as pervasive environmental contaminants detected in air, water, food, and even human tissues such as blood and placenta. These particles are now recognized as potential health hazards to humans. Due to their high surface area and ability to adsorb toxic substances, microplastics can act as vectors for heavy metals and persistent organic pollutants, many of which are established carcinogens. Evidence from animal models links microplastic exposure to oxidative stress, inflammation, immune disruption, and tissue damage, mechanisms implicated in cancer pathogenesis. Although direct causal links in humans need investigation, microplastics have been associated with occupational cancer risks and shown to interfere with cellular and metabolic processes. This emerging health threat underscores the urgent need for regulatory oversight, targeted research, and comprehensive public health strategies to mitigate exposure and assess long-term oncogenic implications.

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