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Papers
11 resultsShowing papers from I.Horbachevsky Ternopil National Medical University
ClearPhysiological and biochemical responses to caffeine and microplastics in Mytilus galloprovincialis
Researchers exposed Mediterranean mussels to caffeine and microplastics both separately and together to measure their combined effects. The combination caused greater oxidative stress and changes in cell function than either pollutant alone. While focused on mussels, the study is relevant to human health because mussels are widely eaten as seafood and can accumulate both microplastics and chemical contaminants.
Reductive stress and cytotoxicity in the swollen river mussel (Unio tumidus) exposed to microplastics and salinomycin
This study exposed freshwater mussels to microplastics and the antibiotic salinomycin, both alone and combined, and found that the mixture caused more severe cellular damage including disrupted antioxidant defenses and signs of programmed cell death. When heat stress was added, the harmful effects became even more unpredictable. The research demonstrates how microplastics can interact with other pollutants and environmental stressors in ways that are difficult to predict.
Combined effect of microplastic, salinomycin and heating on Unio tumidus
Researchers studied how microplastics interact with a common veterinary antibiotic and elevated water temperatures to affect freshwater mussels. While microplastics and the antibiotic alone caused mild stress, the combination under warmer conditions dampened the mussels' protective enzyme responses rather than amplifying them. This finding highlights that the effects of microplastics cannot be studied in isolation, as real-world conditions involve multiple stressors that interact in complex and sometimes unexpected ways.
Alleviation of specific responses in the combined exposure of freshwater mussel Unio tumidus to psychoactive substances and microplastics
Researchers exposed freshwater mussels to a combination of common psychoactive substances (caffeine and chlorpromazine) and microplastics to see how the mixture affected their biology. Individually, each pollutant caused oxidative damage and disrupted cellular processes, but the combined mixture surprisingly reduced some of these harmful effects. The study suggests that pollutant interactions in real-world conditions can produce unexpected outcomes that differ from single-pollutant studies.
Indication of the impact of environmental stress on the responses of the bivalve mollusk Unio tumidus to ibuprofen and microplastics based on biomarkers of reductive stress and apoptosis
Researchers compared freshwater mussels from clean and contaminated sites exposed to microplastics and ibuprofen, finding that chronically stressed populations showed altered biomarker responses for reductive stress and apoptosis, highlighting how environmental history modulates pollutant sensitivity.
Stress responses of bivalve mollusc Unio tumidus from two areas to ibuprofen, microplastic and their mixture
Researchers examined stress responses of freshwater mussels from clean and contaminated sites to ibuprofen, microplastic, and their mixture, finding that population history influenced responses and that mussels from contaminated areas showed greater sensitivity to combined stressors.
ЧУТЛИВА РЕАКЦІЯ ПРІСНОВОДНИХ МОЛЮСКІВ UNIO TUMIDUS НА ДІЮ СУМІШІ ПСИХОАКТИВНИХ РЕЧОВИН ТА МІКРОПЛАСТИКУ
Researchers exposed freshwater mussels (Unio tumidus) to microplastics, caffeine, chlorpromazine, and their mixture for 14 days and measured biochemical biomarkers of stress and toxicity. All exposures caused toxicity (lysosomal membrane instability, cholinesterase inactivation, altered Zn/Cu ratios), with MP notably increasing glutathione and superoxide dismutase levels, and the combined mixture showing cumulative negative effects on phenol oxidase.
Biochemical basis of resistance to multiple contaminations in the native and invasive populations of Dreissena polymorpha
This study compared native and invasive populations of the zebra mussel Dreissena polymorpha in their biochemical tolerance to multiple simultaneous stressors including microplastics, examining how antioxidant and detoxification mechanisms differ between populations.
Biochemical responses of the Dreissena polymorpha from municipal pond to caffeine, microplastics, and heating in single and combined exposures
Researchers exposed zebra mussels (Dreissena polymorpha) from a municipal pond to caffeine, microplastics, and elevated temperature, finding that microplastics alter caffeine bioavailability and that combined exposures produce distinct biochemical stress responses compared to individual pollutants.
Reductive stress and apoptotic activities in bivalve mollusc Unio tumidus exposed to the combination of microplastics, antibiotic salinomycin and heating
This ecotoxicology study exposed freshwater mussels (Unio tumidus) to a combination of microplastics, the antibiotic salinomycin, and elevated temperature to test how multiple stressors interact. Combined exposure caused greater oxidative stress, disrupted zinc-copper balance, reduced lysosomal integrity, and altered apoptosis-related enzyme activity compared to individual stressors. The results demonstrate that real-world conditions — where organisms face plastics alongside other pollutants and warming — can produce compounded harm greater than any single factor alone.
Population-dependent stress response of bivalve mollusc Unio tumidus to ibuprofen, microplastic and their mixture
Researchers exposed freshwater mussels (Unio tumidus) from both pristine and contaminated populations to ibuprofen, polyethylene microplastics, and their combination for 14 days, comparing antioxidant enzyme responses, oxidative damage markers, and lysosomal stability. They found population-dependent differences in stress responses, with the contaminated population showing more pronounced reactions to ibuprofen and the pristine population responding more strongly to microplastics alone.