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Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Environmental Sources Human Health Effects Marine & Wildlife Remediation Sign in to save

ЧУТЛИВА РЕАКЦІЯ ПРІСНОВОДНИХ МОЛЮСКІВ UNIO TUMIDUS НА ДІЮ СУМІШІ ПСИХОАКТИВНИХ РЕЧОВИН ТА МІКРОПЛАСТИКУ

Scientific Issue Ternopil Volodymyr Hnatiuk National Pedagogical University Series Biology 2025 Score: 48 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Viktoria Martyniuk, Viktoria Martyniuk, Viktoria Martyniuk, Оksana Stoliar Kateryna Yunko, Viktoria Martyniuk, Viktoria Martyniuk, Viktoria Martyniuk, Vira Khoma, Kateryna Yunko, Viktoria Martyniuk, Оksana Stoliar Viktoria Martyniuk, Viktoria Martyniuk, Vira Khoma, Kateryna Yunko, Kateryna Yunko, Viktoria Martyniuk, Lesya Gnatyshyna, Vira Khoma, Vira Khoma, Kateryna Yunko, Viktoria Martyniuk, Оksana Stoliar Vira Khoma, Vira Khoma, Vira Khoma, Vira Khoma, Kateryna Yunko, Kateryna Yunko, Lesya Gnatyshyna, Vira Khoma, Vira Khoma, O. Mykhalyuk, O. Mykhalyuk, Lesya Gnatyshyna, Halyna Tulaidan, Lesya Gnatyshyna, Lesya Gnatyshyna, Оksana Stoliar Lesya Gnatyshyna, Lesya Gnatyshyna, Vira Khoma, Halyna Tulaidan, Halyna Tulaidan, Оksana Stoliar Vitaliy Baranovskyi, Mykola Gladiuk, Оksana Stoliar O. Mykhalyuk, Lesya Gnatyshyna, Alla Mudra, Оksana Stoliar Mykola Gladiuk, O. Mykhalyuk, Halyna Tulaidan, Оksana Stoliar Оksana Stoliar Alla Mudra, Оksana Stoliar Lesya Gnatyshyna, Оksana Stoliar Оksana Stoliar Оksana Stoliar

Summary

Researchers exposed freshwater mussels (Unio tumidus) to microplastics, caffeine, chlorpromazine, and their mixture for 14 days and measured biochemical biomarkers of stress and toxicity. All exposures caused toxicity (lysosomal membrane instability, cholinesterase inactivation, altered Zn/Cu ratios), with MP notably increasing glutathione and superoxide dismutase levels, and the combined mixture showing cumulative negative effects on phenol oxidase.

Study Type Environmental

This study investigates the effects of psychoactive substances and microplastics (MP) on the aquatic environment using swollen river mussels (Unio tumidus) as bioindicators. Mussels were exposed to microplastic, caffeine, chlorpromazine and their mixture for 14 days and biochemical biomarkers of stress and toxicity were analysed. All exposures caused the signs of toxicity, indicated as the loss of lysosomal membrane stability, inactivation of choline esterase, and decrease of the Zn/Cu ratio. All exposures, particularly MP, increased the glutathione level, indicating the involving of low weight cellular thiols in the stress response. Exposure to MP induced superoxide dismutase, and mixture decreased phenol oxidase activity, confirming the negative cumulative effect of the combine exposure.

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