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Article Tier 2 Gut & Microbiome Marine & Wildlife Nanoplastics Sign in to save

Intestinal uptake of polystyrene (PS) and polyethylene terephthalate (PET) nanoplastic particles in the Atlantic salmon (Salmo salar) parr and post-smolt, and translocation of PET nanoplastic particles to the circulatory system and liver in parr.

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This Norwegian study examined the uptake of polystyrene and polyethylene terephthalate nanoplastic particles across the intestinal epithelium of Atlantic salmon, finding that PET particles could translocate to the circulatory system and liver. The results raise concerns about nanoplastic bioavailability in commercially important fish species that are consumed by humans.

Body Systems
Study Type In vivo

Mikro- (20 µm – 5 mm) og nano- (< 20 µm) plast utgjør i dag en stor miljøbekymring gjennom akkumulering i marine miljø. Nyere studier viser også at marine vertebrater og invertebrater inntar plastpartikler og at disse distribueres til organer, potensielt med skadelige effekter på organismens celler og vev. Til tross for økt kunnskap er opptaksmekanismene for plastpartikler over tarmepitelet i fisk ukjent. Denne studien hadde til hensikt å undersøke opptak av polystyren (PS) og polyetylen terephthalate (PET) – nanoplastpartikler over tarmepitel hos par og post-smolt av Atlanterhavslaks (Salmo salar). Studien undersøkte også distribusjon av PET-nanoplastpartikler til sirkulasjonssystemet, lever, hodenyre og milt hos parr. En Ex vivo pilotstudie med bruk av Ussing-kammer bekreftet opptak av polystyren (0,5 µm) og PET – partikler i post-smolt. Et in vivo fôringseksperiment bekreftet videre opptak av ≤ 2 µm PET-nanoplastpartikler i tarmvev og distribusjon til sirkulasjonssystemet og lever hos parr. Partikler distribuert til tarmvev og sirkulasjonssystem ble observert sammen med leukocytter, som kan indikere gjenkjenning og initiering av immunsystemet. Resultatene viser at behovet for videre forskning på de cellulære opptaksmekanismer og effekter i Atlanterhavslaks eksponert for nanoplast er stort, spesielt med tanke på fiskevelferd.

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