We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Demonstrating the translocation of nanoplastics across the fish intestine using palladium-doped polystyrene in a salmon gut-sac
AI summary Read the abstract
Researchers used palladium-doped polystyrene nanoplastics to quantitatively measure nanoplastic uptake across the fish intestine in a salmon gut-sac model. The study found that between 200 and 700 million nanoplastics entered the intestinal tissue within four hours, with a fraction passing completely through the gut wall, providing evidence that nanoplastics can potentially distribute throughout the body.
Fish are widely reported to ingest microplastics with low levels accumulating in the tissues, but owing to analytical constraints, much less is known about the potential accumulation of nanoplastics via the gut. Recently, the labelling of plastics with inorganic metals (e.g., palladium) has allowed measurements of nanoplastic uptake. The aim of the current study was to quantitatively assess the uptake of nanoplastics by the fish gut using palladium-doped nanoplastics (with a mean hydrodynamic radius of 202 ± 7 nm). By using an ex vivo gut sac exposure system, we show that in 4 h between 200 and 700 million nanoplastics (representing 2.5-9.4% of the administered nanoplastics dose) can enter the mucosa and muscularis layers of the intestine of salmon. Of the particles taken up, up to 700,000 (representing 0.6% of that taken into the tissue) of the nanoplastics passed across the gut epithelium of the anterior intestine and exit into the serosal saline. These data, generated in highly controlled conditions provide a proof-of-concept study, suggesting the potential for nanoplastics to distribute throughout the body, indicating the potential for systemic exposure in fish.
More Papers Like This
Experimental evidence that polystyrene nanoplastics cross the intestinal barrier of European seabass
AI summary Read the abstract
Researchers provided direct experimental evidence that polystyrene nanoplastics can cross the intestinal barrier of European seabass using ex vivo intestinal preparations. The study showed that nanoplastics translocated across the intestinal epithelium from both median and distal gut segments. The findings demonstrate a mechanism by which nanoplastics could gain access to the bloodstream and internal organs in fish.
Intestinal uptake of polystyrene (PS) and polyethylene terephthalate (PET) nanoplastic particles in the Atlantic salmon (Salmo salar) parr and post-smolt, and translocation of PET nanoplastic particles to the circulatory system and liver in parr.
AI summary Read the abstract
This Norwegian study examined the uptake of polystyrene and polyethylene terephthalate nanoplastic particles across the intestinal epithelium of Atlantic salmon, finding that PET particles could translocate to the circulatory system and liver. The results raise concerns about nanoplastic bioavailability in commercially important fish species that are consumed by humans.
Uptake, distribution and elimination of palladium-doped polystyrene nanoplastics in rainbow trout (Oncorhynchus mykiss) following dietary exposure
AI summary Read the abstract
Researchers tracked the uptake, tissue distribution, and elimination of palladium-doped polystyrene nanoplastics in rainbow trout during dietary exposure and depuration. The study found that nanoplastics accumulated primarily in the intestinal tissues and were also detected in the liver, gallbladder, and kidney, with incomplete clearance after the depuration period.
Translocation of 14C-polystyrene nanoplastics into fish during a very-low concentration dietary exposure
AI summary Read the abstract
Researchers used carbon-14 labeled polystyrene nanoplastics to trace their accumulation in rainbow trout fed a diet containing very low concentrations of the particles over two weeks. They found that nanoplastics translocated from the gut into internal organs, with significantly elevated radioactivity detected in the hind intestine and liver by day 14. The study demonstrates that even at extremely low dietary concentrations, nanoplastics can cross the intestinal barrier and distribute to fish tissues.
Ultra-low dietary exposure to 14C-labelled polystyrene: evidencing translocation of nanoplastics in fish
AI summary Read the abstract
Researchers synthesized carbon-14 radiolabelled polystyrene nanoplastics and fed them to rainbow trout at an ultra-low dietary concentration of 5.9 µg polystyrene/kg feed for two weeks, measuring radioactivity in mid intestine, hind intestine, kidney, and liver at days 3, 7, and 14 via liquid scintillation counting. Significantly elevated radioactivity was detected in the hind intestine and liver of exposed fish by day 14, with liver tissue equivalent to 1.8 µg polystyrene/g dry weight, demonstrating translocation of nanoplastics from the gut to systemic organs even at environmentally relevant low exposures.
Research digests by email
When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.