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Article
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AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button.
Tier 2
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Original research — experimental, observational, or case-control study. Direct primary evidence.
Environmental Sources
Gut & Microbiome
Human Health Effects
Nanoplastics
Policy & Risk
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Quantifying Nanoplastic Toxicity Using Gold-Core Polystyrene Nanoparticles: In vivo Evaluation and Human Risk Extrapolation
International Journal of Nanomedicine
2025
Yingzi Cui,
Xiaohan Tong,
Jiawang Ding,
Boqing Li,
W. Wang,
Chunlei Ma,
Zhiqin Li,
Ying Zhang,
Ying Zhang
Summary
Researchers used gold-core polystyrene nanoparticles as a dual-detectable model to quantify nanoplastic toxicity in vivo, finding that chronic exposure induced intestinal accumulation and systemic toxicity, and used these data to extrapolate human health risk thresholds.
Polymers
Study Type
In vivo
AuPS-NPs replicate PS-NPs toxicity and enable quantitative risk assessment. Chronic exposure may induce intestinal accumulation and systemic toxicity, underscoring the need for regulatory thresholds to mitigate nanoplastic risks.