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Quantifying Nanoplastic Toxicity Using Gold-Core Polystyrene Nanoparticles: In vivo Evaluation and Human Risk Extrapolation
Summary
Researchers used gold-core polystyrene nanoparticles as a dual-detectable model to quantify nanoplastic toxicity in vivo, finding that chronic exposure induced intestinal accumulation and systemic toxicity, and used these data to extrapolate human health risk thresholds.
AuPS-NPs replicate PS-NPs toxicity and enable quantitative risk assessment. Chronic exposure may induce intestinal accumulation and systemic toxicity, underscoring the need for regulatory thresholds to mitigate nanoplastic risks.
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