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Neurotoxic and Systemic Implications of Microplastics and Nanoparticles: A Path Towards Environmental and Biological Remediation

Acta Scientific Medical Sciences 2025
Ross McD. Young

Summary

This review summarizes evidence that microplastics and nanoparticles accumulate in human tissues including brain, reproductive organs, and the cardiovascular system, causing oxidative stress, neurodegeneration, and systemic toxicity. It discusses the olfactory pathway as a route for MPs to bypass the blood-brain barrier and highlights potential remediation approaches including dietary strategies.

Microplastics (MPs) and nanoparticles pose significant risks to human health, accumulating in tissues and vital organs, including the brain, reproductive organs, and cardiovascular system.MPs, such as polyethylene terephthalate (PET), polyvinyl chloride (PVC), and polystyrene (PS), disrupt cellular function and induce oxidative stress, leading to infertility, neurodegeneration, and systemic toxicity [1,3].Recent evidence highlights the olfactory pathway as a route for MPs to bypass the blood-brain barrier (BBB) and accumulate in the brain, emphasizing their potential role in neurodegenerative diseases [4,5].This article explores the mechanisms of these health effects and highlights Dr. Robert O. Young's "Alkalarian Protocol," including dietary strategies and MasterPeace Zeolite Z in SOLergy Sea Minerals, as potential solutions for detoxification and prevention.Emerging research on MPs' risks and removal strategies is also discussed [6,7].

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