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61,005 resultsShowing papers similar to Microplastics as an Emerging Human Health Risk: Mechanisms, Exposure, and Clinical Evidence
ClearMicroplastics as an Emerging Human Health Risk: Mechanisms, Exposure, and Clinical Evidence
This review examines the growing body of evidence on how microplastics enter the human body through ingestion, inhalation, and skin contact, and have now been detected in blood, lung tissue, placenta, and cardiovascular tissue. Evidence indicates that microplastics may cause harm through oxidative stress, inflammation, and cellular damage, though a direct causal link to specific health conditions has not yet been fully established.
The Impact of Microplastic on Human Health
This review synthesized evidence on microplastic exposure pathways and health effects in humans, finding that microplastics enter the body via ingestion, inhalation, and dermal contact and are associated with oxidative stress, inflammation, genotoxicity, and endocrine disruption.
Mechanistic insight into potential toxic effects of microplastics and nanoplastics on human health
This review summarizes how microplastics and nanoplastics enter the body through breathing, eating, and skin contact, then travel through the bloodstream to deposit in organs. Studies show they can cause oxidative stress, inflammation, immune dysfunction, genetic damage, developmental abnormalities, and potentially cancer, though most evidence comes from cell and animal studies rather than human research.
A review on microplastics and nanoplastics in the environment: Their occurrence, exposure routes, toxic studies, and potential effects on human health
This review summarizes what is known about how microplastics and nanoplastics enter the human body through food, air, and skin contact, and what they do once inside. Studies on cells and animals show these tiny particles can cause oxidative stress, DNA damage, inflammation, and harm to the immune, digestive, reproductive, and nervous systems. The research makes clear that microplastics are not just an environmental problem but a direct concern for human health.
Impact of microplastics and nanoplastics on human health: Mechanistic insights and exposure pathways
This review examines how microplastics and nanoplastics enter the human body through ingestion, inhalation, and skin contact, and deposit in tissues including the lungs, kidneys, and gastrointestinal tract. Evidence indicates these particles can cross embryonic layers and reach the placenta, and may cause inflammation, oxidative stress, metabolic disruptions, and immune system effects upon interaction with biological tissues.
Micro(nano)plastics: an Emerging Burden for Human Health
This review summarizes recent research on how micro- and nanoplastics affect human health, noting that these particles have been found accumulating in the cardiovascular, nervous, reproductive, and digestive systems. The evidence points to oxidative stress and inflammation as key mechanisms of harm, with recent human studies now providing direct evidence of cardiovascular toxic effects from plastic particle exposure.
Human exposure to microplastics: A review on exposure routes and public health impacts
This review examines how microplastics enter the human body through food, air, and skin contact and the health effects they can cause, including oxidative stress, inflammation, hormone disruption, and potential DNA damage. Despite growing evidence of harm, the exact routes plastics take through the body and the cellular mechanisms behind their effects are still not well understood, and there is an urgent need for standardized detection methods.
Micro- and Nanoplastics on Human Health and Diseases: Perspectives and Recent Advances
This review provides a comprehensive overview of how micro- and nanoplastics enter the human body through ingestion, inhalation, and skin absorption, and how they can then travel through the bloodstream to reach virtually every organ. Researchers summarize evidence that these particles can trigger inflammation, oxidative stress, and disruption of hormonal and immune functions. The study emphasizes that the ability of these particles to cross biological barriers and accumulate in tissues makes understanding their long-term health effects an urgent research priority.
Impact of Microplastic Exposure on Human Health: A Systematic Review of Mechanisms, Biomarkers, and Clinical Outcomes
This systematic review found that microplastics have been detected in human blood, placental tissue, and gastrointestinal samples, with proposed health mechanisms including oxidative stress, chronic inflammation, endocrine disruption, and gut microbiome alterations. While direct clinical evidence remains limited, the accumulating laboratory and observational data point to microplastics as a plausible contributor to multiple disease pathways.
Potential Health Impact of Microplastics: A Review of Environmental Distribution, Human Exposure, and Toxic Effects
This review summarizes existing research on how microplastics are found throughout the environment and in human samples, entering the body through food, air, and skin contact. Lab studies in cells and animals show microplastics can cause oxidative stress, DNA damage, immune reactions, brain toxicity, and reproductive harm, and early human health data links microplastic exposure to several chronic diseases.
Cellular and Molecular Mechanisms of Micro- and Nanoplastics Driving Adverse Human Health Effects
This review examines the biological mechanisms by which micro- and nanoplastics may cause harm in humans, including oxidative stress, inflammation, disruption of protective barriers, and immune system problems. Evidence from lab and animal studies suggests these particles can affect the gut, heart, brain, and reproductive systems, though human data is still limited to detecting plastics in tissues rather than proving they cause specific diseases. The authors highlight that most studies use higher doses than people actually encounter, making it important to develop research models that better reflect real-world chronic exposure.
[Human Accumulation and Toxic Effects of Microplastics：A Critical Review].
This review summarizes how microplastics enter the human body through food, drinking water, and air, and where they tend to accumulate in organs and tissues. Researchers found evidence that microplastics can trigger inflammatory responses and oxidative stress in the body. The study calls for more research into the long-term health effects of continuous microplastic exposure in humans.
Impact of microplastics and nanoplastics on human Health: Emerging evidence and future directions
This review summarizes current evidence on how micro- and nanoplastics enter the human body through food, air, and skin contact, and the cellular damage they may cause. While microplastic pollution is a recognized environmental hazard, the authors note that definitive evidence linking plastic particle exposure to specific health outcomes in humans is still limited and more realistic exposure studies are needed.
The potential toxicity of microplastics on human health
This review summarizes the latest evidence on how microplastics enter the human body and cause toxic effects, with growing concern since the COVID-19 pandemic dramatically increased exposure through disposable masks. Microplastics have now been detected in human blood, lungs, placenta, and feces, and research suggests they may cause harm through inflammation, oxidative stress, and disruption of normal cell function.
Microplastics and Human Health: A Comprehensive Review on Exposure Pathways, Toxicity, and Emerging Risks
This comprehensive review examines microplastic exposure pathways in humans, methods of detection, and the potential toxic effects on various biological systems. The study highlights growing evidence that microplastics can enter the body through ingestion, inhalation, and dermal contact, and may affect multiple organ systems, though significant uncertainties remain about long-term health outcomes.
Microplastics in Human Tissues: Sources, Distribution, Toxicological Effects, and Health Implications
Researchers reviewed the growing body of evidence that microplastics accumulate in human tissues — including lung, blood, placenta, breast milk, and heart tissue — where they can trigger inflammation, oxidative stress, and cell death. The review highlights urgent knowledge gaps around how plastic particles move through the body and what their long-term health effects may be.
Microplastics and Nanoplastics as Environmental Contaminants of Emerging Concern: Potential Hazards for Human Health
This review covers how microplastics and nanoplastics enter humans through food, air, and skin contact, accumulating in the body over time. Inhaled particles can damage the lungs from the upper airways down to the deepest air sacs, and prolonged exposure has been linked to chronic inflammation, autoimmune disease, atherosclerosis, and cancer. The authors call for source reduction, material substitution, and better filtration to reduce exposure.
Effects of Microplastics on Human Physiology: Mechanisms of Toxicity and Health Risks
This systematic review summarizes research on how microplastics affect human body systems, covering studies from 2000 to 2025. The evidence shows that microplastics have been found in blood, placenta, and reproductive tissues, and can trigger inflammation, oxidative stress, and immune responses. While more research is needed, the findings suggest microplastics may contribute to chronic health conditions through multiple biological pathways.
Microplastics and Nanoplastics Contamination
This review summarizes the state of knowledge on human exposure to microplastics and nanoplastics, covering ingestion, inhalation, and skin contact as entry routes, and detailing how these particles have been detected in human blood, organs, and the placenta. The evidence points to chronic health risks including oxidative stress, inflammation, immune disruption, and potential genotoxicity, with the skin identified as an underexplored but potentially significant exposure pathway.
Environmental exposure to microplastics: An overview on possible human health effects
This review examines the potential health effects of human exposure to microplastics through ingestion, inhalation, and skin contact. Researchers found that microplastic exposure may cause oxidative stress, inflammation, and immune system disruption, with the body's inability to break down synthetic particles potentially leading to chronic inflammation. The study emphasizes that while evidence of harm is growing, microplastic toxicity varies greatly depending on particle properties, concentration, and individual susceptibility.
[Clinical impact of microplastic exposure in humans].
This review summarized clinical evidence on the health impacts of microplastic exposure in humans, covering routes of entry (air, food, contact) and the range of organ systems affected. It concluded that while data are still emerging, current evidence supports concern about microplastic accumulation and its potential to cause inflammation, oxidative stress, and systemic health effects.
Adverse Outcome Phenomena and Toxicity Mechanisms of Micro and Nanoplastics in Human Health
This review examines the growing evidence that micro- and nanoplastics can enter the human body through food, water, and air, and may contribute to harmful biological effects. Researchers found that these tiny particles can trigger oxidative stress, inflammation, and disruption of hormonal and immune systems in laboratory studies. The study highlights the need for a unified research approach to better understand how microplastic exposure may affect long-term human health.
Micro(Nano)Plastics as Carriers of Toxic Agents and Their Impact on Human Health
This review compiles evidence on how micro- and nanoplastics act as carriers of potentially toxic agents and enter the human body through inhalation, ingestion, and dermal absorption. Evidence indicates that continuous exposure to these particles can lead to bioaccumulation and negative health alterations, with recent research detecting microplastics even in human placental tissue.
Exposure Pathways, Systemic Distribution, and Health Implications of Micro- and Nanoplastics in Humans
This review summarizes how micro- and nanoplastics enter the human body through food, air, and skin, then distribute to organs throughout the body. Research in animal and cell models shows these particles can cause oxidative stress, inflammation, brain toxicity, reproductive problems, and potentially cancer, though standardized methods for assessing real-world human health risks are still needed.