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61,005 resultsShowing papers similar to Mitigation of Environmental Exposure, Pollutants, and Endocrine Disruptors to Reproductive Health: A Literature Review
ClearEnvironmental Pollution, Endocrine Disruptors, and Metabolic Status: Impact on Female Fertility—A Narrative Review
This narrative review synthesizes evidence on how environmental pollutants—including fine particulate matter, BPA, phthalates, PFAS, and microplastics—impair female fertility by reducing ovarian reserve, implantation rates, and assisted reproductive technology success, particularly when combined with metabolic conditions.
Environmental Chemicals and Female Reproductive Health: Unraveling Mechanisms and Societal Impacts — A Narrative Review
This narrative review examined how per- and polyfluoroalkyl substances, heavy metals, pesticides, microplastics, and other environmental chemicals disrupt female reproductive health through mechanisms including oxidative stress, hormonal disruption, and epigenetic modifications. The authors reviewed impacts on ovarian function, menstrual regularity, fertility, and pregnancy outcomes.
Microplastics in ovarian function and ozone-based mitigation strategies: Emerging evidence and translational implications
This review synthesized emerging evidence that microplastics accumulate in human follicular fluid, oocytes, placenta, and semen, causing oxidative stress, mitochondrial dysfunction, and meiotic disruption in reproductive cells, and discussed ozone-based strategies as potential mitigation approaches.
Plastics and its effect to women reproductive systems
This article reviews how plastic pollution, including microplastics and the hormone-disrupting chemicals they contain, may affect women's reproductive health. It connects widespread plastic use to endocrine disruption, menstrual irregularities, and fertility concerns, though much of the evidence comes from laboratory and animal studies.
The effects of exposure to microplastics on female reproductive health and pregnancy outcomes: A systematic review and meta-analysis
This meta-analysis pools data from multiple studies to assess how microplastic exposure affects female reproductive health and pregnancy outcomes. The findings suggest that microplastic accumulation may be linked to adverse effects on fertility and pregnancy, highlighting an important and underexplored area of concern for women's health.
Implications of environmental toxicants on ovarian follicles: how it can adversely affect the female fertility?
This review examines how environmental toxicants, including endocrine disrupting chemicals, heavy metals, agrochemicals, and chemicals used in plastic and cosmetic industries, can adversely affect female fertility. Researchers found that these substances can interfere with follicle development and lead to conditions like polycystic ovary syndrome, premature ovarian insufficiency, and meiotic defects. The study highlights the difficulty of isolating individual risk factors since multiple toxicants often share common pathways of reproductive harm.
Environmental determinants of male infertility: emerging threats and technological interventions
This review examines how environmental contaminants, including microplastics, air pollution, heavy metals, and endocrine-disrupting chemicals, may contribute to declining male fertility. The study suggests these environmental toxins can impair sperm function through oxidative stress, hormonal imbalance, and inflammation, and highlights the need for integrating environmental exposure data into fertility assessments.
Female exposure to microplastics in the atmospheric environment: Endocrine disrupting toxicity and its risk regulation strategies
Researchers quantified the female endocrine-disrupting potential of six common types of atmospheric microplastics and their chemical additives. They found that polyamide and PET microplastics, along with bisphenol-based antioxidant additives, were the primary contributors to endocrine disruption risk. The study also identified a modified substitute compound with 37% lower risk and analyzed the molecular mechanisms by which microplastics interact with cell membranes to cause hormonal disruption.
Overview of Development and Reproductive Toxicology Caused by Chemicals and Pollutants
This review examined 15 eligible studies on developmental and reproductive toxicology caused by chemical, water, and air pollutants, following PRISMA guidelines to synthesize evidence on how harmful substances affect human health and ecology. A favorable correlation was found between chemical and environmental pollutants and adverse health outcomes across all three pollution categories.
Developmental and Reproductive Toxicology due to Chemicals and Pollutants
This systematic review examined 15 studies on the developmental and reproductive toxicology of chemical, water, and air pollutants using PRISMA guidelines, identifying favorable correlations between exposure to diverse contaminants and adverse human health outcomes. The authors synthesize evidence across three pollutant categories to highlight the broad reproductive and developmental risks posed by environmental contamination.
Molecular Mechanisms of Environmental Pollutants in Human Health for Unravelling the Pathophysiology of Chronic Diseases
This review examined the integrated molecular mechanisms by which environmental pollutants—including heavy metals, persistent organic pollutants, endocrine disruptors, and microplastics—contribute to chronic diseases such as cancer, cardiovascular disease, and neurodegenerative conditions. The authors found that multiple pollutant classes converge on oxidative stress, epigenetic modification, and inflammatory signaling as shared pathogenic pathways.
Concerning influences of micro/nano plastics on female reproductive health: focusing on cellular and molecular pathways from animal models to human studies
This review summarizes research showing that micro- and nanoplastics can harm the female reproductive system in multiple ways, from reducing ovarian reserves and disrupting hormone balance to accumulating in the placenta and breast milk. Animal studies show these particles trigger oxidative stress and inflammation in reproductive tissues, and human studies have confirmed their presence in placental tissue and infant feces, raising concerns about effects on fertility and fetal development.
The role of environmental toxins in infertility: Insights from cutting-edge research
Researchers reviewed the effects of environmental toxins including bisphenol A, pesticides, heavy metals, microplastics, and electromagnetic fields on human fertility. The study found that these substances have been linked to both male and female infertility through various mechanisms, and highlights the need for greater awareness and regulatory action to reduce exposure to these reproductive toxicants.
Measuring the Impact of Microplastics in the Citarum River on Women's Reproductive Health: A Chronic Exposure Biomarker Study in the Community
Researchers studied women of reproductive age living near Indonesia's heavily polluted Citarum River to assess how chronic microplastic exposure affects reproductive health. They found elevated microplastic levels in river water, sediment, fish, and biological samples, with higher exposure linked to increased oxidative stress, inflammation, reduced anti-Mullerian hormone levels, and menstrual cycle disturbances. The findings indicate a dose-response pattern connecting long-term microplastic exposure with biological stress and reproductive dysfunction.
A review of the impact of micro‐ and nanoplastics on female reproduction: What we know and gaps in knowledge
This review examines what is known about how micro- and nanoplastics affect female reproductive health. Animal studies show these particles accumulate in ovarian tissue, disrupt hormones, and cause oxidative stress, leading to hormonal imbalances and ovarian damage, though research in humans is still limited.
"Unseen Dangers: The Effects of Micro- and Nanoplastics on Human Reproductive Health - A Narrative Review"
This review examines the effects of micro- and nanoplastics on human reproductive health, covering evidence from in vitro, animal, and epidemiological studies showing that plastic particles can disrupt hormone signaling, sperm function, ovarian development, and placental integrity.
Impact of microplastics on female reproductive health: insights from animal and human experimental studies: a systematic review
This systematic review of 15 experimental studies found that microplastic exposure significantly impairs ovarian function, decreases fertility rates, and disrupts hormone levels in female subjects. Several studies also reported negative effects on embryo development and offspring health, though study quality varied and more rigorous research is needed to confirm mechanisms.
Advances in understanding the reproductive toxicity of endocrine-disrupting chemicals in women
This review examines how endocrine-disrupting chemicals such as bisphenol A, phthalates, and triclosan may interfere with the female reproductive system. Evidence indicates that these chemicals, found widely in the environment, can disrupt hormone function and may contribute to adverse reproductive outcomes, though the precise mechanisms are still being studied.
Environmental Risk Factors for Infertility Focusing on Egypt: A Narrative Review
This narrative review examined environmental risk factors for infertility in Egypt, identifying heavy metals, pesticides, and microplastics as emerging concerns and summarizing epidemiological and mechanistic evidence linking environmental exposure to reproductive impairment.
Innovations in minimally invasive gynecologic surgery: Benefits and challenges
This review examines how environmental factors—including endocrine-disrupting chemicals that are commonly associated with plastic additives and microplastic particles—impair reproductive health in both males and females and reduce the success of assisted reproductive technologies. The findings highlight microplastics and their chemical cargo as a meaningful contributor to the global rise in infertility.
Reproductive toxicity and related mechanisms of micro(nano)plastics in terrestrial mammals: Review of current evidence.
This review of terrestrial mammal studies found that micro- and nanoplastics induce reproductive toxicity through oxidative stress, inflammation, endocrine disruption, and DNA damage, affecting both male and female fertility. In males, effects include blood-testis barrier disruption and impaired spermatogenesis, while females show compromised oocyte maturation, ovarian fibrosis, and diminished ovarian reserve, with particles also capable of crossing the maternal-fetal interface.
Microplastics - The Human Cost
This PRISMA-guided review examined human health consequences of microplastic exposure, synthesizing 2018–2024 literature to identify inflammatory, endocrine-disrupting, and potential carcinogenic effects, and calling for expanded clinical and epidemiological research to quantify health risks in humans.
PFAS Toxicity and Female Reproductive Health: A Review of the Evidence and Current State of Knowledge
This review synthesizes recent evidence on the connection between per- and polyfluoroalkyl substances (PFAS) exposure and female reproductive health. The evidence suggests that PFAS exposure is associated with reduced fertility, increased risk of miscarriage, and altered menstrual cycle dynamics through mechanisms including endocrine disruption and oxidative stress. The review emphasizes the need for further research and policy changes to mitigate PFAS exposure and protect reproductive health.
Combined exposure to microplastics and pesticides with endocrine-disrupting potential: evidence of interaction, reproductive biomarkers, and tissue bioaccumulation in humans and animal models
This review study examines how tiny plastic particles (microplastics) and certain pesticides might work together to disrupt hormones and affect fertility in humans and animals. The research suggests these common pollutants may be more harmful when combined than when encountered separately, potentially impacting reproductive health. Understanding these interactions is important because people are exposed to both microplastics and pesticides daily through food, water, and the environment.