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61,005 resultsShowing papers similar to Invisible invaders: unveiling the carcinogenic threat of microplastics and nanoplastics in colorectal cancer-a systematic review
ClearImage 2_Invisible invaders: unveiling the carcinogenic threat of microplastics and nanoplastics in colorectal cancer-a systematic review.png
This systematic review examines the potential link between microplastics and colorectal cancer. It found that humans ingest over 70,000 microplastic particles annually, and that higher concentrations of micro- and nanoplastics have been observed in colorectal tumor tissues compared to healthy tissue, suggesting a possible connection worth further investigation.
Image 1_Invisible invaders: unveiling the carcinogenic threat of microplastics and nanoplastics in colorectal cancer-a systematic review.png
This systematic review examines the potential link between microplastics and colorectal cancer. It found that humans ingest over 70,000 microplastic particles annually, and that higher concentrations of micro- and nanoplastics have been observed in colorectal tumor tissues compared to healthy tissue, suggesting a possible connection worth further investigation.
Image 3_Invisible invaders: unveiling the carcinogenic threat of microplastics and nanoplastics in colorectal cancer-a systematic review.png
This systematic review examines the potential link between microplastics and colorectal cancer. It found that humans ingest over 70,000 microplastic particles annually, and that higher concentrations of micro- and nanoplastics have been observed in colorectal tumor tissues compared to healthy tissue, suggesting a possible connection worth further investigation.
Orally Ingested Micro- and Nano-Plastics: A Hidden Driver of Inflammatory Bowel Disease and Colorectal Cancer.
This review synthesizes evidence linking ingested micro- and nano-plastics to inflammatory bowel disease and colorectal cancer risk, proposing that microplastics act as a hidden driver of gut inflammation in vulnerable populations. The authors argue that intestinal accumulation of microplastics triggers immune and oxidative stress pathways that contribute to disease progression.
Microplastics and Colorectal Cancer: Presence in Human Colorectal Tissues and Associations with Tumor Biology- A Systematic Review
This review of 13 studies found that tiny plastic particles called microplastics are present in human colon tissues, with higher amounts found in cancerous tumors compared to healthy tissue. The research suggests these plastic particles may contribute to colon cancer development by causing inflammation and creating conditions that help tumors grow. While more research is needed to prove a direct cause-and-effect relationship, this highlights growing concerns about how plastic pollution in our environment and food supply might affect human health.
Impact of micro- and nanoplastics on gastrointestinal diseases: Recent advances
This review summarizes how micro- and nanoplastics can harm the digestive system by causing oxidative stress, inflammation, cell death, and disruption of gut bacteria. These connected pathways can damage the intestinal lining and may contribute to conditions like inflammatory bowel disease and colorectal cancer. The findings highlight the importance of understanding how everyday plastic exposure through food and water could affect gut health over time.
Microplastics: an often-overlooked issue in the transition from chronic inflammation to cancer
This review explores how microplastics that accumulate in the human body may trigger long-lasting inflammation, which is a known driver of cancer development. The authors describe how microplastics can disrupt the gut microbiome, activate immune responses, and alter signaling pathways in ways that could promote tumor growth over time.
Microscopic menace: exploring the link between microplastics and cancer pathogenesis
This review examines the growing evidence linking microplastic exposure to cancer development in humans. Microplastics can accumulate in the body and trigger inflammation, oxidative stress, and other biological changes associated with tumor growth. While more clinical research is needed, the review highlights that microplastics should be taken seriously as a potential factor in cancer risk.
The clinical relevance of microplastic exposure on colorectal cancer: A systematic review
This systematic review of four studies found that microplastic accumulation in colorectal cancer tissue (25.9-32.2 particles/g) was significantly higher than in healthy controls, with polyamide, polycarbonate, and polypropylene as the most common polymers detected. While a causal relationship has not been established, the evidence points to microplastics as a potential environmental factor in colorectal cancer development.
Microplastics and Cancer: A Comprehensive Review of Their Impact on Tumor Progression and Mechanisms of Carcinogenesis
This comprehensive review examines the growing body of evidence linking microplastic exposure to various types of cancer, including colorectal, lung, liver, and breast cancers. Researchers found that microplastics and nanoplastics may promote tumor progression through mechanisms including oxidative stress, chronic inflammation, and disruption of cellular signaling pathways. While the evidence is still emerging, the study highlights the need for further research into the potential cancer-related risks of widespread microplastic exposure.
Microplastics as emerging carcinogens: from environmental pollutants to oncogenic drivers
This review examines growing evidence that microplastics and nanoplastics may play a role in cancer development, with these particles found in human tumor tissues from the lungs, colon, stomach, breast, and other organs. The particles appear to promote cancer through chronic inflammation, oxidative stress, DNA damage, and disruption of key cancer-related signaling pathways. While direct proof of causation in humans is still lacking, the accumulating evidence from lab studies, animal experiments, and human tissue analysis suggests microplastics deserve serious attention as potential contributors to cancer risk.
The Relationship Between Microplastics and Nanoplastics with Cancer: An Emerging Health Concern
This review explores the emerging relationship between micro- and nanoplastic exposure and cancer risk in humans. Researchers summarized evidence suggesting that microplastics can carry carcinogenic substances and may trigger inflammatory and oxidative stress pathways linked to tumor development. The study highlights that while early evidence raises concern, more research is needed to establish clear causal connections between plastic particle exposure and specific cancer types.
Microplastic Exposure and Its Dual Impact on Metabolic Syndrome and Pathways of Colorectal Carcinogenesis: A Systematic Review of Epidemiological, Experimental, and Mechanistic Evidence
This systematic review examines evidence linking microplastic exposure to both metabolic syndrome and colorectal cancer pathways. It found a biologically plausible connection between microplastic exposure and these conditions, though a direct clinical link to cancer has not yet been established.
Microplastics: An emerging environmental risk factor for gut microbiota dysbiosis and cancer development?
This review examines how microplastics may disrupt the gut microbiome and immune system in ways that could promote cancer development. Evidence from recent studies suggests microplastics can cause chronic inflammation, alter the balance of gut bacteria, and trigger molecular pathways linked to several cancer types including lung, liver, breast, and colon cancer. While more human research is needed, the review highlights a concerning connection between microplastic exposure, gut health, and cancer risk.
A Comprehensive Narrative Review of Potential Gastrointestinal Adverse Effects From Micro(nano) Plastic Exposure
This narrative review synthesizes evidence on gastrointestinal adverse effects of micro- and nanoplastic exposure, examining how these particles interact with gut microbiota, mucosal barriers, and immune tissue to contribute to inflammatory bowel disease, liver disease, and colorectal cancer risk.
The hidden poison - microplastic : Inflammatory catalyst of cancer development
This review discusses how microplastics act as inflammatory agents within biological tissues, summarizing evidence that ingested and inhaled microplastics can trigger oxidative stress, immune responses, and chronic inflammation in humans and animals.
From Exposure to Oncogenesis: the Role of Microplastics and Associated Pollutants in Cancer - a Literature Review
This literature review examined the growing evidence linking microplastic exposure to cancer development. Microplastics have been found in human lung, liver, and colon tissue, and research suggests they may promote cancer through chronic inflammation, oxidative stress, and by carrying known carcinogens like heavy metals and persistent organic pollutants into the body.
Could Microplastics Be a Driver for Early Onset Colorectal Cancer?
This paper explores whether microplastics could be contributing to the rising rates of colorectal cancer in people under 50. The timing of this increase lines up with the mass production of plastics starting in the 1950s, and microplastics are known to disrupt the gut lining and interact with gut bacteria in ways that could promote cancer. While not proven, the authors argue this connection deserves urgent research given how much plastic humans now ingest.
Microplastics and the Rising Tide of Early‐Onset Colorectal Cancer: Exploring the Environmental Gut Connection
This paper explores the potential connection between microplastic exposure and the rising rates of early-onset colorectal cancer. The study discusses how microplastics may interact with the gut environment, suggesting that further research is needed to understand whether environmental microplastic contamination could be contributing to this emerging health trend.
Micro(nano)plastics pollution and human health: How plastics can induce carcinogenesis to humans?
This review examines how microplastics and nanoplastics enter the human body through food, water, and air, and how they may contribute to cancer development. Common plastic types like polystyrene and PVC, along with toxic chemicals they carry such as PAHs and PCBs, have been linked to DNA damage, oxidative stress, and inflammation, all of which can promote cancer. The paper highlights that while the evidence is growing, more research is needed to understand the full cancer risk from chronic microplastic exposure.
The hidden threat: Microplastics and cancer biology
This review synthesizes current research on the potential links between micro- and nanoplastic exposure and cancer biology, examining how these particles may contribute to tumor development in organs including the gut, lungs, skin, liver, kidney, and brain. The study suggests that chronic exposure to plastic particles can trigger molecular changes such as oxidative stress, inflammation, and DNA damage that are associated with cancer initiation, though clear causal evidence in humans is still lacking.
Effect of microplastics and nanoplastics in gastrointestinal tract on gut health: A systematic review.
This systematic review of 30 in vitro studies found that microplastics and nanoplastics cause size- and concentration-dependent damage to human gastrointestinal cells, including increased oxidative stress, mitochondrial dysfunction, inflammation, and apoptosis. Smaller particles consistently showed greater cellular uptake and biological effects, though chronic low-dose exposure generally produced minimal impacts.
To Waste or Not to Waste: Questioning Potential Health Risks of Micro- and Nanoplastics with a Focus on Their Ingestion and Potential Carcinogenicity
Researchers reviewed how micro- and nanoplastics ingested through food travel through the gut, disrupt the microbiome, trigger inflammation, and may act as carriers for toxic chemicals — a 'Trojan Horse' effect — potentially raising cancer risk. The authors call for a rethinking of consumer culture alongside further scientific investigation.
Do microplastics (MPs) and nanoplastics (NPs) directly contribute to human carcinogenesis?
This review examines whether microplastics and nanoplastics could directly contribute to cancer development in humans. Evidence from lab and animal studies shows these particles can cause DNA damage, chronic inflammation, oxidative stress, and disrupt important cancer-related signaling pathways. While a direct causal link to human cancer has not been proven yet, the review argues that microplastics should be considered potential cancer-promoting agents that warrant urgent further research.