We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Papers
61,005 resultsShowing papers similar to The Impact of Microplastics on Biological Systems: A Focus on Extracellular Vesicles and miRNA Profiles
ClearMicroplastic and Extracellular Vesicle Interactions: Recent Studies on Human Health and Environment Risks
This review explores the newly discovered relationship between microplastics and extracellular vesicles, tiny particles that cells use to communicate with each other. Evidence indicates that microplastics can alter how these vesicles are distributed and what molecular signals they carry, potentially disrupting normal cell communication. Understanding this interaction could provide important insights into how microplastic exposure may contribute to inflammation, metabolic changes, and other health effects.
Cellular and Systemic Impacts of Microplastics and Nanoplastics
This review systematically examined the cellular and systemic health impacts of micro- and nanoplastics, covering uptake mechanisms, organ distribution, and effects on inflammation, oxidative stress, and endocrine function. The authors conclude that MNPs pose credible risks to multiple body systems and call for stronger regulatory action.
Cellular and Systemic Effects of Micro- and Nanoplastics in Mammals—What We Know So Far
This review summarized known cellular and systemic effects of micro- and nanoplastics in mammals, finding that while ingestion is common, knowledge of health impacts remains limited, with oxidative stress and inflammation as the most reported biological responses.
Micro- and nanoplastics: origin, sources of intake and impact on human health (literature review)
This literature review synthesizes mechanisms by which micro- and nanoplastics interact with living organisms, examining their physicochemical properties, routes of human exposure, and documented health effects across multiple organ systems.
Cellular Impact of Micro(nano)plastics on Human Health: A Review.
This review examined how micro(nano)plastics (MNPs) entering the human body through ingestion, inhalation, and skin contact affect cells and tissues. It synthesized evidence of oxidative stress, inflammation, DNA damage, and endocrine disruption associated with MNP exposure.
Human exposure to micro- and nanoplastic: biological effects and health consequence
This review summarized the biological effects and health consequences of human exposure to micro- and nanoplastics, covering routes of uptake (ingestion, inhalation, dermal), cellular toxicity mechanisms, and systemic health risks identified in recent experimental and epidemiological studies.
Micro-and Nanoplastic-Induced Biochemical Toxicity: Emerging Mechanisms and Health Risks Across Biological Systems
This comprehensive review synthesizes current understanding of how micro- and nanoplastics cause biochemical toxicity across biological systems, from plants and invertebrates to vertebrates and humans. Key mechanisms include oxidative stress, membrane disruption, immune activation, genotoxicity, endocrine disruption, and microbiome perturbation, all modulated by particle size, shape, and surface chemistry. The authors highlight critical gaps in standardization, chronic low-dose effect data, and the need for translatable biomarkers for risk assessment.
Plastic pollution and its pathophysiological impacts on mammalian cells
This review examines the pathophysiological impacts of microplastics and nanoplastics on mammalian cells, discussing how environmental degradation of larger plastics generates micro- and nano-scale fragments that enter organisms through ingestion, accumulate via trophic transfer, and cause cellular toxicity. The authors synthesize laboratory evidence on MP and NP interactions with mammalian cells including membrane disruption, inflammation, and genotoxicity.
Oncogenic Role of miRNA by Environmental Exposure to Plasticizers: A Systematic Review.
This systematic review summarizes recent findings on how exposure to plasticizers can alter microRNA expression in ways that promote cancer development. The research is directly relevant to microplastic concerns because plasticizers are chemical additives used in plastic manufacturing, and as microplastics break down in the body, these chemicals may be released and affect gene regulation.
Cellular and Systemic Impacts of Microplastics and Nanoplastics
This review synthesized evidence on how micro- and nanoplastics cause cellular and systemic harm through inflammation, oxidative stress, mitochondrial dysfunction, and endocrine disruption across multiple organ systems. The authors emphasize that exposure is ubiquitous and that health impacts are no longer speculative.
Multiple Effects, Pathways, and Potential Health Risks from Environmental Microplastic Exposure
This review synthesizes nearly two decades of research on the multiple pathways through which environmental microplastics affect human and ecological health, including chemical toxicity, physical impacts, and potential roles as carriers of pathogens and contaminants.
Extracellular vesicles as mediators of metabolomic changes in response to PET microplastics
Researchers fed piglets PET microplastics (a common plastic used in food packaging) and found that the particles changed the chemical signals carried by extracellular vesicles, which are tiny messengers that cells use to communicate with each other. The altered signals disrupted fat processing, energy production, sugar metabolism, and hormone production. This reveals a previously unknown way that microplastics could cause widespread disruption throughout the body.
Micro- and Nanoplastics as Emerging Environmental Determinants of Human Health: A Narrative Review
This narrative review explores evidence linking micro- and nanoplastic exposure to potential adverse health outcomes across multiple organ systems. Researchers found that increasing experimental and observational data suggest these particles may be associated with harmful biological effects. The review calls for further research to clarify the clinical significance of microplastic exposure for public health.
Micro and Nanoplastics on Human Health and Diseases: Perspectives and Recent Advances
This review covers how micro- and nanoplastic particles enter the human body through ingestion, inhalation, infusion, and skin absorption, distribute to virtually all tissues and organs via the circulatory system, and cause health impacts including inflammatory responses, cellular damage, and endocrine disruption.
Micro- and Nanoplastics as Emerging Environmental Determinants of Human Health: A Narrative Review
This narrative review explores the existing evidence linking micro- and nanoplastic exposure to potential health-related outcomes across multiple organ systems. Researchers found increasing experimental and observational evidence indicating that exposure to these particles may be associated with adverse biological effects. The review highlights the need for further clinical research to understand the full scope of microplastic impacts on human health.
Untoward Effects of Micro- and Nanoplastics: An Expert Review of Their Biological Impact and Epigenetic Effects
This expert review examined the biological and epigenetic effects of micro- and nanoplastics on living organisms. The study suggests that while intestinal uptake of plastic particles appears relatively low and size-dependent, nanoplastics may dysregulate molecular signaling pathways, alter gut microbiota composition, and induce transgenerational epigenetic changes potentially linked to metabolic disorders.
New insights into the potential effects of PET microplastics on organisms via extracellular vesicle-mediated communication
Researchers discovered that PET microplastics can be transported within the body through tiny cellular packages called extracellular vesicles, which cells naturally use to communicate with each other. They found that exposure to PET microplastics altered the content and behavior of these vesicles, potentially allowing plastic particles to reach tissues beyond the initial site of exposure. The study reveals a previously unknown biological pathway through which microplastics may spread their effects throughout organisms.
The Impact of Microplastics and Nanoplastics on Human Health: A Follow-Up Study Focusing on Endocrine, Nervous, and Immune Systems
This review examines evidence for microplastic and nanoplastic impacts on the endocrine, nervous, and immune systems, documenting how particles detected in human organs can disrupt hormone signaling, induce neuroinflammation, and alter immune function.
Health impacts of micro- and nanoplastics: key influencing factors, limitations, and future perspectives
This review systematically analyzed how the physicochemical properties of micro- and nanoplastics — including size, shape, surface charge, and polymer type — determine their toxicological impacts across biological systems. The authors argue that property-based frameworks are essential for predicting MNP health risks and designing relevant research.
Microplastics and human health: unraveling the toxicological pathways and implications for public health
This review pulls together recent research on how microplastics enter the human body and cause cellular damage through inflammation, oxidative stress, and direct cell injury. The authors highlight that microplastics can also amplify the harmful effects of other environmental pollutants they carry, creating combined health risks that are greater than either threat alone.
Exposure and Health Effects of Microplastics in Humans
This doctoral thesis investigates exposure levels and health effects of microplastics in humans, synthesizing analytical chemistry and toxicological evidence on microplastic presence in human tissues and their potential biological impacts.
Effects of Nanoplastics on Human Health: A Comprehensive Study
This comprehensive review examines the diverse health effects of nanoplastics, drawing on toxicology, environmental science, and epidemiology to document how these particles interact with human biological systems. The authors conclude that nanoplastics represent a growing public health concern requiring further investigation.
[Effects and Mechanisms of Polystyrene Microplastics on Extracellular Antibiotic Resistance Genes in Wastewater].
This Chinese-language study reviewed the effects and mechanisms of polystyrene microplastics on extracellular vesicle production and composition, examining how microplastic exposure alters cell-to-cell communication pathways. The research contributes to understanding subcellular responses to microplastic exposure in biological systems.
Microplásticos y nanoplásticos: mecanismos de bioacumulación y toxicidad
This systematic review summarizes current scientific evidence on how micro- and nanoplastics interact with living systems. It found that these tiny particles can accumulate in biological tissues and trigger toxic responses, underscoring growing concerns about their potential effects on human health.