Papers

20 results
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Systematic Review Tier 1

Effect of microplastics and nanoplastics in gastrointestinal tract on gut health: A systematic review.

This systematic review provides the first comprehensive look at how microplastics and nanoplastics affect the human gut using laboratory models. The findings help explain how these tiny particles may damage the digestive tract lining and trigger inflammation, which is important for understanding the health risks of swallowing microplastics in food and water.

2025 PubMed
Article Tier 2

The infiltration of microplastics in human systems: Gastrointestinal accumulation and pathogenic impacts

This review focuses on how microplastics accumulate in the human digestive system and what health problems they might cause. The authors explain that people ingest microplastics through food, water, and air, and these particles may trigger inflammation, disrupt gut bacteria, and potentially contribute to gastrointestinal diseases.

2025 Heliyon 10 citations
Article Tier 2

Micro(nano)plastics in food system: potential health impacts on human intestinal system.

This review assessed how micro(nano)plastics in the human food system reach the intestine and accumulate in the gut, summarizing evidence that they can alter intestinal barrier function, trigger inflammation, and disrupt the gut microbiome, with implications for long-term digestive health.

2024 Critical reviews in food science and nutrition
Systematic Review Tier 1

Microplastics in the Gastrointestinal Tract: A Systematic Review

This systematic review summarizes research on microplastics found in the human gastrointestinal tract. It highlights that microplastics are accumulating in our digestive systems through food and water, and calls for urgent research to understand how these particles may affect gut health and overall well-being.

2025 Journal of Gastroenterology and Hepatology
Article Tier 2

[Effect of microand nanoplastics on the gastrointestinal mucosa and intestinal microbiome].

This review examines how micro- and nanoplastics entering through the food chain affect the gastrointestinal tract, finding evidence of disruption to gut mucosal integrity and intestinal microbiome composition, with implications for digestive health and systemic immune function.

2023 PubMed 2 citations
Systematic Review Tier 1

Impacts of microplastics on gut health: Current status and future directions

This systematic review found consistent evidence across mouse, fish, and earthworm models that microplastics disrupt gut microbiota composition, impair intestinal barrier integrity, and trigger gastrointestinal inflammation. The correlation between microplastic exposure and gut health deterioration was statistically significant across all animal models examined.

2025 Indian Journal of Gastroenterology 2 citations
Article Tier 2

Micro(nano)plastics and their potential impact on human gut health: a narrative review

This narrative review synthesizes evidence on how microplastics and nanoplastics affect the human gut, discussing ingestion routes, gut barrier interactions, microbiome disruption, and potential systemic health effects.

2024 Preprints.org
Article Tier 2

Ingested microplastics pose a potentially serious risk to the gastrointestinal microenvironment

This review argues that ingested microplastics pose a serious potential risk to the gastrointestinal microenvironment by disrupting the gut microbiome, irritating the intestinal lining, and potentially carrying toxic additives and adsorbed chemicals into the digestive tract. Given that human microplastic ingestion is now unavoidable, the authors call for urgent research into gastrointestinal health effects.

2020 The Journal of Immunology 2 citations
Article Tier 2

Micro(nano)plastics and Their Potential Impact on Human Gut Health: A Narrative Review

This review summarizes research on how micro- and nanoplastics affect the gut, finding that they can damage the intestinal lining, trigger immune responses, and disrupt the balance of beneficial gut bacteria in both cell studies and animal models. Since humans are primarily exposed to microplastics through food and food packaging, understanding these gut effects is essential for assessing the true health risks of plastic pollution.

2024 Current Issues in Molecular Biology 62 citations
Systematic Review Tier 1

Recent Progress in Intestinal Toxicity of Microplastics and Nanoplastics: Systematic Review of Preclinical Evidence

This systematic review of animal studies from 2021 to 2024 found growing evidence that swallowed microplastics and nanoplastics can damage the gut. Effects include inflammation, weakened gut barriers, oxidative stress, and disrupted gut bacteria. These findings suggest that the plastic particles found in our food could pose a risk to digestive health, though more research with realistic exposure levels is needed.

2024 Microplastics 13 citations
Article Tier 2

Interaction between microplastics and microorganism as well as gut microbiota: A consideration on environmental animal and human health

This review explores how microplastics interact with microorganisms in the environment and within the gut, examining implications for both animal and human health. Researchers found that microplastics can alter gut microbiota composition, promote the spread of antibiotic-resistant bacteria, and amplify the toxicity of other environmental pollutants. The study suggests that the interaction between microplastics and gut microorganisms is an important emerging area for understanding health risks.

2019 The Science of The Total Environment 405 citations
Article Tier 2

A Comprehensive Narrative Review of Potential Gastrointestinal Adverse Effects From Micro(nano) Plastic Exposure

This narrative review synthesizes evidence on gastrointestinal adverse effects of micro- and nanoplastic exposure, examining how these particles interact with gut microbiota, mucosal barriers, and immune tissue to contribute to inflammatory bowel disease, liver disease, and colorectal cancer risk.

2025 Clinical Gastroenterology and Hepatology
Systematic Review Tier 1

The ant that may well destroy a whole dam: a systematic review of the health implication of nanoplastics/microplastics through gut microbiota

This systematic review summarizes existing research on how nanoplastics and microplastics disrupt gut bacteria in various organisms. The findings show that plastic particle exposure consistently alters gut microbiome composition, which in turn affects the host's immune function, metabolism, and overall health. These gut bacteria changes may be a key pathway through which microplastics harm human health.

2025 Critical Reviews in Food Science and Nutrition 2 citations
Article Tier 2

Animal exposure to microplastics and health effects: A review

Researchers reviewed how microplastic exposure affects animals across terrestrial and aquatic environments, finding that species suffer physical harm, chemical contamination from pollutants that stick to plastic surfaces, inflammation, and behavioral changes. Because microplastics accumulate up the food chain, the review warns that animals entering the human food supply may carry these particles into our bodies.

2024 Emerging contaminants 117 citations
Article Tier 2

Effects of Microplastics on Animal Health and Nutrition

This review summarizes the current understanding of how microplastic ingestion affects animal health across multiple species including livestock, poultry, and aquatic organisms. Researchers found that microplastics can cause inflammation, oxidative stress, and disruption of gut function in animals, with smaller particles posing greater risks due to their ability to cross biological barriers. The study suggests that microplastic contamination in feed and water sources is an emerging concern for animal agriculture and nutrition.

2024 Erciyes Üniversitesi Veteriner Fakültesi Dergisi 2 citations
Article Tier 2

Microplastic: A potential threat to human and animal health by interfering with the intestinal barrier function and changing the intestinal microenvironment

This review summarizes current research on how microplastics disrupt the gut environment in both animals and humans, focusing on damage to the intestinal barrier. Studies show that microplastic exposure can cause oxidative damage, inflammation, destruction of the gut lining, thinning of the protective mucus layer, and disruption of beneficial gut bacteria. While direct human evidence is still limited, the growing body of animal research suggests that microplastics could pose a meaningful threat to intestinal health.

2021 The Science of The Total Environment 225 citations
Article Tier 2

Review: interactions between microplastics and the gastrointestinal microbiome

This review summarizes existing research on how microplastics interact with the gut microbiome in humans, mice, chickens, and aquatic animals. Evidence suggests that gut bacteria can break microplastics into smaller pieces, which may make them more likely to cross the intestinal wall and enter the body. The disruption of the gut microbiome by microplastics is particularly concerning because balanced gut bacteria are essential for immune function, digestion, and overall health.

2024 Italian Journal of Animal Science 14 citations
Article Tier 2

Impact of micro- and nanoplastics on gastrointestinal diseases: Recent advances

This review summarizes how micro- and nanoplastics can harm the digestive system by causing oxidative stress, inflammation, cell death, and disruption of gut bacteria. These connected pathways can damage the intestinal lining and may contribute to conditions like inflammatory bowel disease and colorectal cancer. The findings highlight the importance of understanding how everyday plastic exposure through food and water could affect gut health over time.

2025 European Journal of Internal Medicine 7 citations
Systematic Review Tier 1

Effect of microplastics and nanoplastics in gastrointestinal tract on gut health: A systematic review.

This systematic review of 30 in vitro studies found that microplastics and nanoplastics cause size- and concentration-dependent damage to human gastrointestinal cells, including increased oxidative stress, mitochondrial dysfunction, inflammation, and apoptosis. Smaller particles consistently showed greater cellular uptake and biological effects, though chronic low-dose exposure generally produced minimal impacts.

2025 The Malaysian journal of pathology
Article Tier 2

Effects of microplastics and nanoplastics on marine environment and human health

This review examines the effects of micro- and nanoplastics on marine environments and human health, covering sources, environmental fate, and biological impacts. Researchers summarize evidence that these particles can cause oxidative stress, inflammation, and disruption of gut microbiota in exposed organisms. The study highlights that while the full extent of health risks remains uncertain, the pervasive presence of plastic particles in food, water, and air makes continued research a public health priority.

2020 Environmental Science and Pollution Research 237 citations