Papers

61,005 results
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Article Tier 2

Micro(nano)plastics pollution and human health: How plastics can induce carcinogenesis to humans?

This review examines how microplastics and nanoplastics enter the human body through food, water, and air, and how they may contribute to cancer development. Common plastic types like polystyrene and PVC, along with toxic chemicals they carry such as PAHs and PCBs, have been linked to DNA damage, oxidative stress, and inflammation, all of which can promote cancer. The paper highlights that while the evidence is growing, more research is needed to understand the full cancer risk from chronic microplastic exposure.

2022 Chemosphere 367 citations
Article Tier 2

Plastic pollution: why is it a public health problem?

This commentary argues that plastic pollution is a public health problem due to the widespread human exposure to microplastics and plastic-associated chemicals, calling for regulatory action to address the full lifecycle of plastics including production, use, and disposal.

2021 Australian and New Zealand Journal of Public Health 17 citations
Article Tier 2

Microscopic menace: exploring the link between microplastics and cancer pathogenesis

This review examines the growing evidence linking microplastic exposure to cancer development in humans. Microplastics can accumulate in the body and trigger inflammation, oxidative stress, and other biological changes associated with tumor growth. While more clinical research is needed, the review highlights that microplastics should be taken seriously as a potential factor in cancer risk.

2025 Environmental Science Processes & Impacts 8 citations
Article Tier 2

The Impact of Environmental Factors on Cancer Risk: A Comprehensive Review

This paper is not about microplastics in a specific research sense; it is a broad review of how environmental factors influence cancer risk, with no substantive microplastic content evident from the available abstract.

2023
Systematic Review Tier 1

From Exposure to Oncogenesis: the Role of Microplastics and Associated Pollutants in Cancer - a Literature Review

This literature review examined the growing evidence linking microplastic exposure to cancer development. Microplastics have been found in human lung, liver, and colon tissue, and research suggests they may promote cancer through chronic inflammation, oxidative stress, and by carrying known carcinogens like heavy metals and persistent organic pollutants into the body.

2025 International Journal of Innovative Technologies in Social Science
Article Tier 2

Comment on “cancer may be induced by microplastics-sorbed polycyclic aromatic hydrocarbons?”

This commentary examines the plausibility of microplastics acting as carriers of carcinogenic polycyclic aromatic hydrocarbons that could induce oral cancer, reviewing evidence on microplastic ingestion, tissue distribution, and the genotoxic potential of sorbed compounds. The author calls for mechanistic studies to clarify cancer risk pathways.

2024 Oral Oncology Reports
Article Tier 2

The Relationship Between Microplastics and Nanoplastics with Cancer: An Emerging Health Concern

This review explores the emerging relationship between micro- and nanoplastic exposure and cancer risk in humans. Researchers summarized evidence suggesting that microplastics can carry carcinogenic substances and may trigger inflammatory and oxidative stress pathways linked to tumor development. The study highlights that while early evidence raises concern, more research is needed to establish clear causal connections between plastic particle exposure and specific cancer types.

2024 International Journal of Hematology and Oncology 3 citations
Article Tier 2

Microplastic Contamination: A Rising Environmental Crisis With Potential Oncogenic Implications

This review examines how microplastics detected in human tissues — blood, placenta, and organs — may act as vectors for carcinogens, including adsorbed heavy metals and persistent organic pollutants, and discusses emerging evidence linking MP accumulation to oncogenic processes.

2025 Cureus
Article Tier 2

From exposure to oncogenesis: a review on the multifaceted roles of microplastics in tumor initiation and progression

This review examined the evidence linking microplastic exposure to tumor initiation and progression, covering physical, chemical, and inflammatory mechanisms by which MPs may promote oncogenesis. The authors conclude that while current evidence is largely preclinical, accumulating data warrant serious concern about microplastics as environmental carcinogens.

2025 Journal of Translational Medicine
Article Tier 2

Rising Concern About the Carcinogenetic Role of Micro-Nanoplastics

This review examined the emerging concern that micro- and nanoplastics may play a role in cancer development, either directly or by carrying chemical carcinogens into the body. Researchers noted that while direct evidence is still limited, the rising incidence of certain cancers in younger populations alongside increasing environmental plastic contamination has raised important questions. The study calls for more focused research to understand whether long-term microplastic exposure may contribute to cancer risk and what preventive measures might be warranted.

2024 International Journal of Molecular Sciences 5 citations
Article Tier 2

Microplastics: an often-overlooked issue in the transition from chronic inflammation to cancer

This review explores how microplastics that accumulate in the human body may trigger long-lasting inflammation, which is a known driver of cancer development. The authors describe how microplastics can disrupt the gut microbiome, activate immune responses, and alter signaling pathways in ways that could promote tumor growth over time.

2024 Journal of Translational Medicine 46 citations
Article Tier 2

Rising Cancer Impact and Pollution as Hazards

This paper is not directly about microplastics; it is a broad overview of environmental causes of cancer, covering air and water pollution, industrial exposures, and workplace chemicals, and calls for regulatory action to reduce carcinogenic exposures.

2023 Preprints.org 1 citations
Article Tier 2

Plastic pollution-Microplastics: Cancer related issues

This review examines how microplastics may contribute to cancer risk, summarizing evidence that ingested microplastics can cross the gut epithelium, accumulate in tissues, induce oxidative stress and inflammation, and carry carcinogenic chemical additives.

2025 World Journal of Biology Pharmacy and Health Sciences
Article Tier 2

Microplastics as emerging carcinogens: from environmental pollutants to oncogenic drivers

This review examines growing evidence that microplastics and nanoplastics may play a role in cancer development, with these particles found in human tumor tissues from the lungs, colon, stomach, breast, and other organs. The particles appear to promote cancer through chronic inflammation, oxidative stress, DNA damage, and disruption of key cancer-related signaling pathways. While direct proof of causation in humans is still lacking, the accumulating evidence from lab studies, animal experiments, and human tissue analysis suggests microplastics deserve serious attention as potential contributors to cancer risk.

2025 Molecular Cancer 7 citations
Article Tier 2

Rising Concern About the Carcinogenetic Role of Micro‐Nanoplastics

This review raised concerns about the carcinogenic potential of micro- and nanoplastics, synthesizing evidence that these particles can induce DNA damage, oxidative stress, and cellular transformation. It called for accelerated research into whether microplastic exposure increases human cancer risk.

2024 Preprints.org 1 citations
Article Tier 2

The hidden poison - microplastic : Inflammatory catalyst of cancer development

This review discusses how microplastics act as inflammatory agents within biological tissues, summarizing evidence that ingested and inhaled microplastics can trigger oxidative stress, immune responses, and chronic inflammation in humans and animals.

2024 INTERNATIONAL JOURNAL PLANT SCIENCES
Article Tier 2

Exposure to Microplastics is Associated With the Risk of Cancer in Children

Researchers examined the emerging link between microplastic exposure and cancer risk in children, noting that these tiny plastic particles are found in tap water, bottled water, air, and food that children regularly consume. The study raises concern that early-life exposure to microplastics and their chemical additives may contribute to childhood cancer risk.

2025 Journal of Pediatrics Review
Article Tier 2

Insights into the potential carcinogenicity of micro- and nano-plastics.

This review examined existing evidence on the carcinogenic potential of micro- and nano-plastics, finding studies demonstrating genotoxicity, oxidative DNA damage, disruption of cell signaling, and tumor-promoting effects, while noting that direct human carcinogenicity data remain limited and mechanistic pathways require further investigation.

2023 Mutation research. Reviews in mutation research
Article Tier 2

Role of the Synergistic Interactions of Environmental Pollutants in the Development of Cancer

This review examines how mixtures of environmental pollutants, including microplastics, may interact synergistically to promote cancer development, even when individual pollutant levels are below established safety thresholds. The study suggests that the combined effects of multiple low-dose exposures deserve greater attention in risk assessment, as traditional single-pollutant evaluations may underestimate the true health risks.

2022 GeoHealth 68 citations