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61,005 resultsShowing papers similar to O Modelo Zebrafish e sua Contribuição ao Meio Ambiente
ClearResearch Progress of Zebrafish Model in Aquatic Ecotoxicology
This review examines how zebrafish are used as model organisms to study the toxic effects of environmental pollutants in water, including microplastics. Zebrafish are ideal because they reproduce quickly, are inexpensive to maintain, and allow researchers to study effects at the genetic, cellular, and whole-organism level. The paper provides a reference guide for scientists choosing model animals for aquatic toxicology research.
Zebrafish as Model Organism in Aquatic Ecotoxicology: Current Trends and Future Perspectives
This review assessed zebrafish as model organisms for aquatic ecotoxicology, summarizing current trends and future directions in using Danio rerio to study the effects of environmental pollutants including microplastics. The authors highlight the zebrafish model's utility for integrating molecular, cellular, and whole-organism responses.
Research progress of model animal zebrafish in toxicity evaluation of microplastics
This review examines the use of zebrafish as a model organism for evaluating the toxicity of microplastics, synthesizing research on how microplastic exposure affects development, reproduction, and physiological function in this well-established vertebrate model. The authors highlight zebrafish as a particularly valuable system for mechanistic toxicology studies given its genetic tractability and the breadth of endpoints assessable across life stages.
The Zebrafish as an Alternative Animal Model for Ecotoxicological Research and Testing
This review highlights zebrafish as a valuable model for studying the toxic effects of environmental contaminants, including microplastics, because they share many biological pathways with humans. Zebrafish embryos, larvae, and adults can be used to screen for harmful effects of pollutants quickly and at multiple life stages. The approach helps researchers understand how microplastics and other environmental contaminants might affect human health without requiring direct human testing.
Zebrafish: An emerging model to study microplastic and nanoplastic toxicity
This review highlights zebrafish as an increasingly valuable model organism for studying the toxic effects of micro- and nanoplastics due to their transparent embryos, genetic similarity to humans, and ease of laboratory use. Researchers summarized existing zebrafish studies showing that plastic particles can cross biological barriers and accumulate in tissues, causing various toxic effects. The study positions zebrafish research as a key tool for advancing our understanding of how plastic particle exposure affects living organisms.
Comprehensive review of ecological risks and toxicity mechanisms of microplastics in freshwater: Focus on zebrafish as a model organism
This comprehensive review examines how microplastics affect zebrafish, a widely used laboratory model, covering impacts on the gut, liver, reproductive system, nervous system, and immune function. Researchers found that microplastics can cause oxidative stress, inflammation, and disruption of gut bacteria across multiple organ systems. The review highlights that zebrafish studies provide valuable insights into the biological mechanisms by which microplastics may affect freshwater organisms and, potentially, human health.
Use of zebrafish (Danio rerio) as a model for research in toxicological studies
This review explains why zebrafish (Danio rerio) are a valuable model organism for toxicology research, summarizing how their biology, genetics, and organ systems resemble those of humans enough to yield insights about human health risks. Zebrafish are widely used in microplastic toxicology studies, and this review provides context for understanding the significance of zebrafish findings for human health. The paper covers applications across disease modeling and environmental toxicology.
Advances of microplastics ingestion on the morphological and behavioral conditions of model zebrafish: A review
This review summarizes research on how microplastic ingestion affects zebrafish, a popular lab animal that shares genetic similarities with humans. Studies show that microplastics cause a range of harmful effects in zebrafish, including abnormal behavior, oxidative stress, immune disruption, and reproductive problems, with smaller particles and higher concentrations causing the most damage. Since zebrafish are used as a model for human health, these findings raise concerns about what similar exposure levels could mean for people.
Danio rerio as a Model Animal for Assessing Microplastic Toxicity
This review examines the use of zebrafish as a model organism for assessing microplastic toxicity, summarizing experimental findings across polymer types and sizes showing that microplastic exposure induces epithelial damage, lipid metabolism disruption, reproductive impairment, and neurobehavioral alterations, and discussing the strengths and limitations of Danio rerio for microplastic hazard assessment.
Behavioral Studies of Zebrafish Reveal a New Perspective on the Reproductive Toxicity of Micro- and Nanoplastics
This review summarizes existing research on how micro- and nanoplastics affect the behavior and reproductive health of zebrafish, a common lab model for studying human biology. The findings suggest that tiny plastic particles can disrupt reproductive behavior and act as hormone-like chemicals, and that behavioral changes in fish may serve as early warning signs of reproductive harm that could be relevant to understanding human health risks.
Advantages of the zebrafish (Danio rerio) model in solving contemporary problems of neurotoxicity, teratotoxicity and genotoxicity of xenobiotics
This paper is not about microplastics per se; it is a Polish-language review of the zebrafish (Danio rerio) model in toxicology, covering its use for assessing neurotoxicity, teratotoxicity, and genotoxicity of xenobiotics including nanoparticles and microplastics, with discussion of the micronucleus and comet assays used to detect genetic damage.
Microplastics in Limnic Ecosystems - Investigation of Biological Fate and Effects of Microplastic Particles and Associated Contaminants in Zebrafish (Danio rerio)-
This doctoral thesis investigated how microplastics and their associated chemical contaminants affect zebrafish (Danio rerio) in freshwater environments, including ingestion, tissue accumulation, and toxicological effects. The research demonstrates that microplastics can act as vectors for pollutants like pesticides and pharmaceuticals, compounding their harmful effects on aquatic organisms.
Nanoplasti̇kleri̇n Sucul Ekosi̇stem Üzeri̇ndeki̇ Etki̇si̇: Zebra Baliği Modellemesi̇
This Turkish-language chapter reviews the effects of nanoplastics on aquatic ecosystems using zebrafish as a model, examining how nano-sized plastic fragments affect development, behavior, reproduction, and organ function. The text traces the origins of nanoplastic pollution from plastic mass production since the mid-twentieth century.
In vivo biotoxicological assessment of nanoplastics and microplastics predicted using the zebrafish model
This review summarises zebrafish studies on the toxicity of nanoplastics and microplastics, covering developmental, reproductive, neurological, and organ-level effects. It discusses how findings in this widely used model organism may predict human health outcomes and calls for standardised exposure protocols.
Zebrafish Insights into Nanomaterial Toxicity: A Focused Exploration on Metallic, Metal Oxide, Semiconductor, and Mixed-Metal Nanoparticles
This review summarizes research on how various nanomaterials, including nano-sized plastics, affect zebrafish, which are commonly used as stand-ins for studying human health effects. Exposure to nanomaterials caused developmental defects, organ damage, behavioral changes, and reproductive problems in zebrafish. These findings help scientists understand the potential health risks of nanomaterial exposure to humans and the environment.
The use of zebrafish to assess water quality and remediation efforts.
Researchers used zebrafish as a model organism to assess the ecotoxicity of wastewater effluents in South Africa, where many treatment plants fail to meet minimum standards, exposing aquatic life to a range of contaminants of emerging concern.
Nanoplastics in the Environment and the Effects on the Zebrafish
This study reviewed the effects of nanoplastic exposure on zebrafish, covering how these tiny particles affect development, organ function, behavior, and reproductive success. Zebrafish are a widely used model organism for toxicology, and findings in this species provide insight into potential effects in other vertebrates including humans.
Small fish, big discoveries: zebrafish shed light on microbial biomarkers for neuro-immune-cardiovascular health
This review highlighted how zebrafish serve as a powerful model for studying gut microbiome links to cardiovascular, neurological, and immune health, identifying microbial biomarkers that could inform future research on environmental stressor impacts including microplastic exposure.
Effects of Microplastics and Nanoplastics on Neurodevelopment and Neurodegeneration in Zebrafish
This review covers how micro- and nanoplastic (MNP) exposure affects neurodevelopment and neurodegeneration in zebrafish, summarising evidence on impaired neurodevelopment, behavioural changes, and markers of neurodegeneration from studies using various polymer types and exposure routes. It frames zebrafish as a key model for understanding MNP neurotoxicity.
Effects of pristine or contaminated polyethylene microplastics on zebrafish development
Researchers examined the effects of both pristine and pollutant-contaminated polyethylene microplastics on zebrafish development through chronic exposure. The study assessed how microplastics, both alone and as carriers of adsorbed organic pollutants, affect developing fish. The findings provide new insights into how contaminated microplastics may create additional routes for toxic compounds to enter aquatic food webs.
Rethinking the relevance of microplastics as vector for anthropogenic contaminants: Adsorption of toxicants to microplastics during exposure in a highly polluted stream - Analytical quantification and assessment of toxic effects in zebrafish (Danio rerio)
Researchers exposed microplastics in a highly polluted stream to assess their role as contaminant vectors, then tested effects on zebrafish, finding that naturally contaminated microplastics had limited additional toxicity compared to the polluted water itself.
Neurotoxicity of Some Environmental Pollutants to Zebrafish
This review examines how environmental pollutants including microplastics, pesticides, and drug residues can damage the nervous system, using zebrafish as a model organism. The studies show that microplastics can cause neurotoxic effects on their own and also increase the brain-damaging potential of other pollutants they carry, which has implications for understanding how these contaminants might affect the human nervous system.
Zebrafish as a Model Organism to Study Nanomaterial Toxicity
This review examines the use of zebrafish as a model organism for studying nanomaterial toxicity, summarizing how zebrafish embryo and larval assays have been applied to assess the biological effects of metal, carbon, and polymer-based nanomaterials.
Accumulation and Distribution of Fluorescent Microplastics in the Early Life Stages of Zebrafish
Researchers tracked the accumulation and distribution of fluorescent microplastics in early life stages of a freshwater organism, finding that microplastics were taken up and distributed across body tissues. The results help explain how microplastics accumulate in young aquatic organisms and potentially affect their development.