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61,005 resultsShowing papers similar to Immunological Responses of Marine Bivalves to Contaminant Exposure: Contribution of the -Omics Approach
ClearOmics insights in responses of bivalves exposed to plastic pollution
This review examined how advanced molecular analysis technologies are being used to understand how bivalves like mussels and oysters respond to microplastic and nanoplastic exposure at the genetic and protein level. Researchers found that plastic pollution disrupts bivalve behavior, metabolism, and reproduction, and that molecular-level analysis can reveal early warning signs of harm not visible through traditional observation. The findings are relevant to both marine conservation and human food safety, since bivalves are widely consumed seafood that accumulate plastic particles.
Elucidating the consequences of the co-exposure of microplastics jointly to other pollutants in bivalves: A review
This review examines studies on the combined effects of microplastics and other pollutants in bivalves, finding that co-exposure often modifies individual toxicant effects and highlighting bivalves as important sentinel species for monitoring complex environmental contamination.
Microplastics in commercial marine bivalves: Abundance, characterization and main effects of single and combined exposure
This review summarizes recent findings on microplastic contamination in commercially valuable marine bivalve species, documenting a wide variety of particle shapes, sizes, colors, and polymer types across multiple species. Researchers found that microplastic exposure, alone or combined with other pollutants, triggers immunological, physiological, behavioral, reproductive, genotoxic, and neurotoxic effects in these organisms. The study calls for harmonized research methodologies to enable better comparison of microplastic contamination levels across studies and regions.
Single and repetitive microplastics exposures induce immune system modulation and homeostasis alteration in the edible mussel Mytilus galloprovincialis
Researchers examined transcriptome-wide gene expression changes in Mediterranean mussels after single and repeated microplastic exposures, finding significant immune system modulation and disruption of cellular homeostasis. The study suggests that both short-term and chronic microplastic exposure can alter immune regulation pathways in filter-feeding bivalves, with repeated exposures showing cumulative effects.
Physiological and transcriptome analysis of Mytilus coruscus in response to Prorocentrum lima and microplastics
The combined effects of diarrhetic shellfish toxin and microplastics on the mussel Mytilus coruscus were assessed at physiological and transcriptomic levels, revealing synergistic disruption of immune function, antioxidant responses, and metabolic pathways. The study provides molecular-level evidence of interactive toxicity between two common coastal contaminants.
Unveiling the hidden impacts: A comprehensive review of microplastic effects on marine bivalves
This review synthesizes research on how microplastics accumulate in marine bivalves through their filter-feeding behavior, covering mechanisms of ingestion, bioaccumulation, oxidative stress induction, immune disruption, and growth inhibition, with implications for food safety given widespread human consumption of bivalves.
Multi-Omics Approach on the Ecotoxicological Assessment of Microplastics
This review examines the application of multi-omics approaches — including genomics, transcriptomics, proteomics, and metabolomics — to the ecotoxicological assessment of microplastics in living organisms. The authors synthesize how these integrated molecular tools are advancing understanding of the mechanistic pathways by which microplastics disrupt biological systems, offering a more comprehensive picture than single-endpoint toxicity studies.
From the raw bar to the bench: Bivalves as models for human health.
This review explores how bivalves such as oysters, mussels, and clams are used as model organisms for biological and ecological research, including their roles as biomonitors for pollution. The paper highlights how the genomic tools now available for studying bivalves are advancing understanding of their responses to environmental stressors including microplastic contamination.
Immunotoxicity and neurotoxicity of bisphenol A and microplastics alone or in combination to a bivalve species, Tegillarca granosa
Researchers investigated the immunotoxicity and neurotoxicity of bisphenol A and microplastics, both alone and in combination, on the blood clam Tegillarca granosa. The study found that co-exposure to both pollutants produced significant impacts on immune and neural biomarkers, suggesting that the combined presence of microplastics and chemical contaminants may pose greater risks to marine invertebrates.
The Eco-Immunological Relevance of the Anti-Oxidant Response in Invasive Molluscs
Not relevant to microplastics — this review examines how antioxidant defence mechanisms in invasive mollusc species help them survive environmental stress and support immune function, with no focus on microplastic exposure.
Hitchhikers in bivalve immune system: Mixed microplastics and nanoplastics triggers hemocyte autophagy
Researchers exposed bivalves to mixed microplastic and nanoplastic suspensions of multiple sizes and quantified the effects on hemocyte immune cell populations over time. Heterogeneous MNP mixtures reshaped hemocyte subpopulations non-additively, altering immune function in ways that single-size exposure studies would not predict.
The impact of microplastics on bivalve mollusks: A bibliometric and scientific review
This review examines how microplastics affect bivalve shellfish like mussels, oysters, and clams, which are important both ecologically and as human food sources. Microplastics disrupt bivalve feeding, growth, reproduction, and immune function, and can also carry other toxic pollutants into their tissues. Since bivalves filter large volumes of water and are often eaten whole by humans, they represent a direct pathway for microplastic transfer from the ocean to our bodies.
Influence of Microplastics on Freshwater Bivalves (Review)
This review analyzed studies on microplastic uptake, bioaccumulation, and biological effects in freshwater bivalves, which serve as both pollution sentinels and vectors for microplastic entry into food webs. The authors found consistent evidence for particle accumulation causing physiological stress, while calling for more standardized exposure protocols to improve cross-study comparability.
Effects of microplastics on physiological performance of marine bivalves, potential impacts, and enlightening the future based on a comparative study
This review examines the effects of microplastics and their chemical additives on the physiology of marine bivalves such as mussels and oysters, including impacts on feeding, reproduction, immunity, and gene expression. Researchers identified significant gaps in the literature, particularly regarding the combined effects of microplastics with other environmental stressors. The study highlights that while individual studies show varied results, the cumulative evidence suggests microplastic exposure can alter key biological functions in these ecologically important organisms.
Immunotoxicity of microplastics and two persistent organic pollutants alone or in combination to a bivalve species
Researchers studied the immunotoxic effects of microplastics and two persistent organic pollutants, benzo[a]pyrene and estradiol, on the bivalve Tegillarca granosa, both individually and in combination. Exposure to microplastics alone altered immune cell counts, phagocytic activity, and expression of immune-related genes. Notably, smaller 500-nanometer microplastics generally worsened the toxicity of the co-pollutants, while larger 30-micrometer particles appeared to mitigate their effects.
Distinguish the toxic differentiations between acute exposure of micro- and nano-plastics on bivalves: An integrated study based on transcriptomic sequencing
Researchers found that nanoplastics are more toxic than microplastics in mussels, causing severe inflammatory responses and greater oxidative stress, with transcriptomic analysis revealing contrasting gene expression patterns between the two particle sizes.
Toxicological effects of microplastics in Litopenaeus vannamei as indicated by an integrated microbiome, proteomic and metabolomic approach
Shrimp (Litopenaeus vannamei) exposed to five microplastic types for 14 days showed gut microbiota shifts (increased Bacteroidetes and Proteobacteria, decreased Firmicutes) and altered haemolymph proteomes, with each MP type producing distinct immune pathway effects.
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This review examines microplastic contamination in coastal and marine environments, focusing on bivalves as sentinel organisms due to their filter-feeding behavior and widespread use as human food, synthesizing evidence on physiological damage across aquatic species and ecological risks from plastic particle transfer through food chains.
Immunotoxicity of petroleum hydrocarbons and microplastics alone or in combination to a bivalve species: Synergic impacts and potential toxication mechanisms
Marine mussels exposed to petroleum hydrocarbons and microplastics separately and together showed that combined exposure caused greater immune suppression and lysosomal damage than either stressor alone, identifying oxidative stress pathways as a key mechanism of joint toxicity.
Bisphenol A and microplastics weaken the antimicrobial ability of blood clams by disrupting humoral immune responses and suppressing hemocyte chemotactic activity
Researchers investigated how bisphenol A and microplastics, alone and combined, affect the immune defenses of blood clams (Tegillarca granosa). They found that both pollutants weakened the clams' antimicrobial ability by disrupting humoral immune responses and reducing the movement of immune cells toward infection sites. The study suggests that co-exposure to these common environmental contaminants could leave marine bivalves more vulnerable to disease.
The stress-immunity axis in shellfish.
This review examines the stress-immunity relationship in shellfish, covering how environmental stressors — including chemical contaminants like microplastics — activate immune responses and affect shellfish health. Since shellfish are consumed by humans and accumulate microplastics from the water they filter, understanding how plastic pollution stresses these animals is important for seafood safety.
Microplastic exposure reshapes the virome and virus–bacteria networks with implications for immune regulation in Mytilus coruscus
Researchers exposed mussels to microplastics for seven days and analyzed how the pollution affected viral communities in their tissues. They found that microplastic exposure suppressed DNA virus diversity while activating RNA viral metabolism, and restructured interactions between bacteria-infecting viruses and opportunistic pathogens. The study suggests that microplastics may influence immune function in shellfish by reshaping the viral community and virus-mediated immune interactions.
Physiological and transcriptomic analyses reveal critical immune responses to hypoxia and sulfide in the haemolymph of clam Tegillarca granosa
This paper is not relevant to microplastics research — it examines how hypoxia and sulfide exposure affect immune responses in blood clams (Tegillarca granosa) at a physiological and transcriptomic level.
Microplastics can aggravate the impact of ocean acidification on the health of mussels: Insights from physiological performance, immunity and byssus properties
Researchers found that the combination of ocean acidification and microplastic exposure weakened mussel immune systems, reduced feeding performance, and degraded the quality of byssus threads used for attachment. The study suggests that co-occurring ocean acidification and microplastic pollution could increase the vulnerability of bivalves to disease and dislodgement, threatening their survival in future marine environments.