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61,005 resultsShowing papers similar to Parental transfer of nanopolystyrene-enhanced tris(1,3-dichloro-2-propyl) phosphate induces transgenerational thyroid disruption in zebrafish
ClearNanoplastics aggravated TDCIPP-induced transgenerational developmental neurotoxicity in zebrafish depending on the involvement of the dopamine signaling pathway
Zebrafish exposed to nanoplastics combined with TDCIPP (a common flame retardant chemical) from embryo to adulthood showed more severe brain development problems than exposure to either pollutant alone. The nanoplastics increased the absorption of the flame retardant and together they disrupted the dopamine signaling pathway in the brain, with toxic effects carrying over to the next generation. This highlights how nanoplastics can amplify the neurotoxicity of other environmental chemicals.
Enhanced toxicity of triphenyl phosphate to zebrafish in the presence of micro- and nano-plastics
Co-exposure of zebrafish to triphenyl phosphate (TPhP) with micro- or nano-polystyrene showed that nano-PS (46 nm) aggravated TPhP-induced liver and gonad enlargement, while micro-PS had minimal effect — suggesting nanoplastics can enhance the toxicity of organophosphate flame retardants.
Interactive transgenerational effects of polystyrene nanoplastics and ethylhexyl salicylate on zebrafish
The combined transgenerational effects of polystyrene nanoplastics and the UV filter ethylhexyl salicylate (EHS) were studied in zebrafish across multiple generations. Nanoplastics affected the bioaccumulation and multigenerational toxicity of EHS, indicating that nanoplastics can modify chemical exposure outcomes across zebrafish generations.
Aging relieves the promotion effects of polyamide microplastics on parental transfer and developmental toxicity of TDCIPP to zebrafish offspring
Researchers discovered that pristine polyamide microplastics promoted the transfer of the flame retardant TDCIPP from parent zebrafish to offspring and increased developmental toxicity, but aging of the microplastics reduced these harmful effects due to changed surface properties.
Toxic effects of polystyrene nanoplastics and polybrominated diphenyl ethers to zebrafish (Danio rerio)
Researchers investigated the individual and combined toxic effects of polystyrene nanoplastics and the flame retardant BDE-47 on zebrafish embryos. They found that co-exposure worsened developmental deformities including pericardial and yolk sac edema, and disrupted gene expression related to detoxification and antioxidant defense. The study suggests that nanoplastics can act as carriers for persistent organic pollutants, amplifying their harmful effects on aquatic organisms.
Adverse adult-onset and multigenerational effects in zebrafish (Danio rerio) developmentally exposed to polystyrene nanoplastics
Researchers raised zebrafish exposed to nanoplastics during early development through to adulthood and found lasting reproductive impairment, heritable hyperactivity in offspring, and molecular changes in male reproductive and brain tissue linked to neurodegenerative disease pathways and endocrine disruption, demonstrating that brief developmental nanoplastic exposure can cause multigenerational harm.
Parental exposure to polystyrene nanoplastics and di(2-ethylhexyl) phthalate induces transgenerational growth and reproductive impairments through bioaccumulation in Daphnia magna
Researchers assessed the transgenerational impacts of parental exposure to polystyrene nanoplastics and the plasticizer DEHP on Daphnia magna over four generations. The study found that combined exposure to nanoplastics and DEHP caused growth and reproductive impairments that persisted across generations through bioaccumulation, suggesting that the ecological consequences of nanoplastic and plasticizer co-contamination may extend well beyond directly exposed organisms.
From mothers to offspring: Polystyrene nanoplastics create a hidden toxic legacy via mitochondrial dysfunction
Researchers exposed female zebrafish to polystyrene nanoplastics before mating with unexposed males and found that maternal exposure at 100 μg/L reduced offspring hatching success and caused developmental defects in the F1 generation raised in clean water, demonstrating transgenerational toxicity via mitochondrial dysfunction.
Transgenerational effects of Nanoplastics and bisphenol A on Zebrafish lipid metabolism: Disruption of the gut Microbiota-liver axis via mTOR pathway
Researchers exposed zebrafish to nanoplastics and bisphenol A, a chemical commonly found in plastics, and tracked the effects across three generations. They found that the combined exposure disrupted fat metabolism, damaged gut bacteria and liver function in the first generation, and these metabolic problems were passed down to offspring that were never directly exposed. The study suggests that nanoplastic and chemical co-exposure may cause health effects that persist across multiple generations.
Metabolic Consequences of Developmental Exposure to Polystyrene Nanoplastics, the Flame Retardant BDE-47 and Their Combination in Zebrafish
Researchers examined how developmental exposure to polystyrene nanoplastics and the flame retardant BDE-47, alone and combined, affects zebrafish metabolism, finding that co-exposure produced distinct metabolic disruptions beyond those caused by either contaminant individually.
Detrimental effects of individual versus combined exposure to tetrabromobisphenol A and polystyrene nanoplastics in fish cell lines
Researchers tested how combined exposure to the flame retardant tetrabromobisphenol A and polystyrene nanoparticles affects freshwater fish cells. They found that co-exposure to even low concentrations of both pollutants caused subtle changes in cell viability and generated oxidative DNA damage. The study suggests that the interaction between nanoplastics and chemical pollutants in aquatic environments may pose compounding risks to fish health.
Polystyrene nanoplastics enhance the toxicological effects of DDE in zebrafish (Danio rerio) larvae
Researchers found that polystyrene nanoplastics enhanced the toxicity of the pesticide metabolite DDE in zebrafish larvae, with co-exposure causing greater developmental abnormalities and oxidative stress than either pollutant alone.
Maternal transfer of nanoplastics to offspring in zebrafish (Danio rerio): A case study with nanopolystyrene
Researchers demonstrated maternal transfer of polystyrene nanoplastics in zebrafish by feeding exposed females and detecting particles in yolk sacs, livers, and guts of offspring, finding that transferred nanoplastics reduced antioxidant enzyme activity and caused bradycardia in embryos without major effects on overall reproductive success.
The joint effect of parental exposure to microcystin-LR and polystyrene nanoplastics on the growth of zebrafish offspring
Adult zebrafish co-exposed to polystyrene nanoplastics and microcystin-LR (MCLR) for 21 days transferred more MCLR to their offspring than MCLR alone, and the nanoplastic-enhanced MCLR parental load correlated with greater growth inhibition and developmental defects in F1 larvae.
Contrasting effects of micro- and nanoplastics on accumulation and toxicity of tris(1,3-dichloro-2-propyl) phosphate in zebrafish embryo revealed by toxicokinetic-toxicodynamic model
Researchers examined how microplastics and nanoplastics differently affect the accumulation and toxicity of the flame retardant TDCIPP in zebrafish embryos. The study found that while microplastics had minimal effect, nanoplastics significantly increased TDCIPP bioaccumulation and enhanced adverse effects on hatching, development, and survival, as validated by toxicokinetic and toxicodynamic modeling.
Female zebrafish (Danio rerio) exposure to polystyrene nanoplastics induces reproductive toxicity in mother and their offspring
Researchers exposed female zebrafish to polystyrene nanoplastics for six weeks and found the particles disrupted sex hormone levels and oocyte development, reducing egg production in the exposed generation and carrying endocrine disruption effects into unexposed offspring through the hypothalamic-pituitary-gonadal axis.
First insight of the intergenerational effects of tri-n-butyl phosphate and polystyrene microplastics to Daphnia magna
Researchers studied the combined effects of polystyrene microplastics and the flame retardant tributyl phosphate on water fleas across multiple generations. They found that co-exposure caused more severe impacts on survival, growth, and reproduction than either contaminant alone, with effects persisting into subsequent generations. The study suggests that microplastics carrying adsorbed chemicals may pose compounding risks to aquatic organisms over time.
Multigenerational effects of combined exposure of triphenyltin and micro/nanoplastics on marine medaka (Oryzias melastigma): From molecular levels to behavioral response
This study exposed marine medaka fish to a combination of micro/nanoplastics and triphenyltin, a toxic chemical used in paints and plastics. The pollutants caused oxidative stress, hormone imbalances, and behavioral changes that carried over to the next generation of fish. The findings show that microplastics combined with other environmental pollutants can cause harm that gets passed down to offspring, raising concerns about long-term effects on marine food webs.
Adverse effects of polystyrene nanoplastic and its binary mixtures with nonylphenol on zebrafish nervous system: From oxidative stress to impaired neurotransmitter system
Researchers investigated the individual and combined effects of polystyrene nanoplastics and the industrial chemical nonylphenol on the zebrafish nervous system over 45 days. Both substances induced oxidative stress and disrupted neurotransmitter systems, with combined exposure generally producing more severe effects on glutamate metabolism and brain tissue damage. The study suggests that the interaction between nanoplastics and co-occurring environmental pollutants can amplify neurotoxic effects in fish.
Effects of polystyrene nanoplastics on the bioaccumulation, distribution and parental transfer of ethylhexyl salicylate
Researchers found that polystyrene nanoplastics affect the bioaccumulation and distribution of the UV filter ethylhexyl salicylate in zebrafish, and that nanoplastics facilitate the parental transfer of this chemical contaminant to offspring.
Mechanisms of parental co-exposure to polystyrene nanoplastics and microcystin-LR aggravated hatching inhibition of zebrafish offspring
Zebrafish parents co-exposed to microcystin-LR and polystyrene nanoplastics produced offspring with greater MCLR accumulation and more severe hatching inhibition than MCLR alone, with nanoplastics acting as a carrier that enhanced toxin transfer to embryos.
Co-exposure to triclosan and polystyrene nanoplastics on neurodevelopmental toxicity and gut microbiota dysbiosis in zebrafish (Danio rerio)
Researchers investigated the combined effects of triclosan and polystyrene nanoplastics on zebrafish development and found that co-exposure worsened neurodevelopmental toxicity beyond the effects of either pollutant alone. The combined exposure caused significant gut microbiota disruption and altered expression of genes involved in neural development, suggesting synergistic toxic effects between these two common environmental contaminants.
Polystyrene nanoplastics mediated the toxicity of silver nanoparticles in zebrafish embryos
Researchers studied how polystyrene nanoplastics interact with silver nanoparticles and affect zebrafish embryo development. They found that nanoplastics can act as carriers for silver nanoparticles in water, and the combination altered patterns of oxidative stress, immune response, and metabolic function compared to either pollutant alone. The study highlights how nanoplastics may change the way other environmental contaminants affect aquatic organisms.
Developmental toxicity and mechanism of polychlorinated biphenyls 126 and nano-polystyrene combined exposure to zebrafish larvae
Researchers exposed zebrafish embryos to a combination of a toxic industrial chemical (PCB126) and nanoplastics and found that the mixture caused more severe developmental problems than either pollutant alone. The nanoplastics appeared to increase the absorption and toxic effects of PCB126, leading to greater heart defects and developmental abnormalities. The study suggests that nanoplastics may worsen the impact of existing chemical pollutants on aquatic life.