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Interactive transgenerational effects of polystyrene nanoplastics and ethylhexyl salicylate on zebrafish
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The combined transgenerational effects of polystyrene nanoplastics and the UV filter ethylhexyl salicylate (EHS) were studied in zebrafish across multiple generations. Nanoplastics affected the bioaccumulation and multigenerational toxicity of EHS, indicating that nanoplastics can modify chemical exposure outcomes across zebrafish generations.
Effects of PS-NPs on bioaccumulation and transgenerational toxicity of EHS to zebrafish.
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Effects of polystyrene nanoplastics on the bioaccumulation, distribution and parental transfer of ethylhexyl salicylate
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Researchers found that polystyrene nanoplastics affect the bioaccumulation and distribution of the UV filter ethylhexyl salicylate in zebrafish, and that nanoplastics facilitate the parental transfer of this chemical contaminant to offspring.
Interactive neurotoxicity of environmentally relevant concentrations of polystyrene nanoplastics and butyl methoxydibenzoyl methane on early zebrafish embryos
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Researchers found that polystyrene nanoplastics and the UV sunscreen chemical BM-DBM interact synergistically to cause neurotoxicity in zebrafish at environmentally relevant concentrations, disrupting nervous system development and gene expression more severely in combination than either pollutant alone.
Parental transfer of nanopolystyrene-enhanced tris(1,3-dichloro-2-propyl) phosphate induces transgenerational thyroid disruption in zebrafish
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Researchers investigated the transgenerational effects of nanoplastics combined with the flame retardant TDCIPP on zebrafish thyroid function. The study found that nanopolystyrene enhanced the bioavailability and toxicity of TDCIPP, and that parental exposure induced thyroid disruption that was passed to offspring, suggesting that nanoplastics may amplify the harmful effects of co-occurring pollutants across generations.
Effects of polystyrene nanoplastics on melanin interference toxicity and transgenerational toxicity of ethylhexyl salicylate based on DNA methylation sequencing
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Researchers found that polystyrene nanoplastics can reduce the melanin-disrupting and transgenerational toxicity of the sunscreen ingredient ethylhexyl salicylate in zebrafish by adsorbing the chemical, while EHS alone inhibited melanin production through the mitfa-tyr signaling cascade.
Synergy under the Sun? Nanoplastics Enhance Estrogenicity of Common UV-Blocker
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Human cells and zebrafish co-exposed to polystyrene nanoplastics and the UV filter homosalate showed higher plastic accumulation in tissues, greater estrogenic activity, and more pronounced gene expression changes than with either exposure alone.
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