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61,005 resultsShowing papers similar to Human and ecological health effects of nanoplastics: May not be a tiny problem
ClearNanoplastics in the Environment: Sources, Fate, Toxicity, Challenges and Mitigation Strategies
This review covers the formation, environmental fate, and health risks of nanoplastics, emphasizing their capacity to penetrate biological barriers and cause oxidative stress, inflammation, DNA damage, and endocrine disruption, alongside current strategies for mitigation.
A review on microplastics and nanoplastics in the environment: Their occurrence, exposure routes, toxic studies, and potential effects on human health
This review summarizes what is known about how microplastics and nanoplastics enter the human body through food, air, and skin contact, and what they do once inside. Studies on cells and animals show these tiny particles can cause oxidative stress, DNA damage, inflammation, and harm to the immune, digestive, reproductive, and nervous systems. The research makes clear that microplastics are not just an environmental problem but a direct concern for human health.
A review on micro- and nanoplastics in humans: Implication for their translocation of barriers and potential health effects
This review compiles evidence showing that micro- and nanoplastics have been found in human blood, lungs, placenta, and other organs, and can cross protective barriers including the blood-brain and placental barriers. The accumulated evidence links these particles to inflammation, oxidative stress, hormone disruption, and potential effects on reproduction and brain health, though more research is needed to determine exact risk levels.
Adverse Outcome Phenomena and Toxicity Mechanisms of Micro and Nanoplastics in Human Health
This review examines the growing evidence that micro- and nanoplastics can enter the human body through food, water, and air, and may contribute to harmful biological effects. Researchers found that these tiny particles can trigger oxidative stress, inflammation, and disruption of hormonal and immune systems in laboratory studies. The study highlights the need for a unified research approach to better understand how microplastic exposure may affect long-term human health.
Cellular and Systemic Effects of Micro- and Nanoplastics in Mammals—What We Know So Far
This review summarized known cellular and systemic effects of micro- and nanoplastics in mammals, finding that while ingestion is common, knowledge of health impacts remains limited, with oxidative stress and inflammation as the most reported biological responses.
Nanoplastics in the Biological System: A Microscopic Menace with an Impact
This chapter examines nanoplastics, ultra-small polymer particles under one micrometer, as widespread environmental pollutants with significant biological consequences. The study reviews evidence from cellular and animal research indicating that nanoplastics can traverse biological barriers, move through air, water, and soil, and induce oxidative stress in living organisms, highlighting their unique mobility compared to larger microplastics.
Micro- and Nanoplastics on Human Health and Diseases: Perspectives and Recent Advances
This review provides a comprehensive overview of how micro- and nanoplastics enter the human body through ingestion, inhalation, and skin absorption, and how they can then travel through the bloodstream to reach virtually every organ. Researchers summarize evidence that these particles can trigger inflammation, oxidative stress, and disruption of hormonal and immune functions. The study emphasizes that the ability of these particles to cross biological barriers and accumulate in tissues makes understanding their long-term health effects an urgent research priority.
Understanding the human health impacts of environmental micro- and nanoplastics
This review summarized current understanding of how micro- and nanoplastic particles enter the human body through food and air, accumulate in tissues, and cause health effects through oxidative stress, inflammation, and endocrine disruption, with a focus on gaps in knowledge about long-term human health impacts.
Advances on micro/nanoplastics and their effects on the living organisms: A review
This review examines the current state of research on how micro- and nanoplastics affect plants, animals, microorganisms, and humans. Researchers found that these tiny plastic particles can cause oxidative stress, inflammation, reproductive problems, and disruption of gut microbiomes across a wide range of species. The study highlights that while significant progress has been made in understanding these effects, major gaps remain in assessing long-term exposure risks at realistic environmental concentrations.
Toxicity and Accumulation of Nanoplastics Materials: A Review of Experimental Evidence Across Biological Systems
This systematic review of studies from 2010 to 2025 found that nanoplastics can penetrate biological barriers and accumulate in tissues across many organisms. Their tiny size makes them especially concerning because they can enter cells, cause oxidative stress and inflammation, and potentially affect organ function in ways that larger plastic particles cannot.
Uncovering layer by layer the risk of nanoplastics to the environment and human health
This review examines how nanoplastics, plastic particles smaller than 100 nanometers, can cross biological barriers like the gut lining and accumulate in vital organs. Once inside the body, nanoplastics can trigger inflammation, oxidative stress, genetic damage, hormone disruption, and immune problems. The authors stress the need for standardized detection methods and long-term studies to fully understand the health risks these tiny particles pose to humans.
Effects of microplastics and nanoplastics on marine environment and human health
This review examines the effects of micro- and nanoplastics on marine environments and human health, covering sources, environmental fate, and biological impacts. Researchers summarize evidence that these particles can cause oxidative stress, inflammation, and disruption of gut microbiota in exposed organisms. The study highlights that while the full extent of health risks remains uncertain, the pervasive presence of plastic particles in food, water, and air makes continued research a public health priority.
Effects of Nanoplastics on Human Health: A Comprehensive Study
This comprehensive review examines the diverse health effects of nanoplastics, drawing on toxicology, environmental science, and epidemiology to document how these particles interact with human biological systems. The authors conclude that nanoplastics represent a growing public health concern requiring further investigation.
Potential Health Impact of Environmentally Released Micro- and Nanoplastics in the Human Food Production Chain: Experiences from Nanotoxicology
This review assesses the potential for micro- and nanoplastics to enter the human food chain, drawing on evidence from studies of food production and related biological systems. Researchers found that while larger microplastics are unlikely to be absorbed by the human body, nanoplastics may be small enough to cross biological barriers and accumulate in tissues. The study highlights that much remains unknown about real-world human exposure levels and calls for more research into the health implications of these tiny particles in food.
How Do Nanoplastics and Microplastics Impact Human Health?
This review examines how nanoplastics and microplastics impact human health not only through direct particle exposure but also indirectly through their degradation of ecosystem services and environmental health. The authors synthesize evidence showing MPs are omnipresent in nature, that NPs are accumulating as MP fragmentation continues, and that the combined direct and indirect pathways represent a growing and multifaceted human health concern.
Environmental fate, ecotoxicity biomarkers, and potential health effects of micro- and nano-scale plastic contamination
This review provides a comprehensive overview of the environmental fate, ecotoxicity biomarkers, and potential health effects of micro- and nanoscale plastic particles. Researchers summarize how these particles move through ecosystems, accumulate in organisms, and trigger biological stress responses including oxidative damage and inflammation. The study emphasizes that while growing evidence points to harmful effects, more research is needed to understand the long-term health implications of chronic low-level exposure.
Cellular and Molecular Mechanisms of Micro- and Nanoplastics Driving Adverse Human Health Effects
This review examines the biological mechanisms by which micro- and nanoplastics may cause harm in humans, including oxidative stress, inflammation, disruption of protective barriers, and immune system problems. Evidence from lab and animal studies suggests these particles can affect the gut, heart, brain, and reproductive systems, though human data is still limited to detecting plastics in tissues rather than proving they cause specific diseases. The authors highlight that most studies use higher doses than people actually encounter, making it important to develop research models that better reflect real-world chronic exposure.
Emergence of Nanoplastic in the Environment and Possible Impact on Human Health
This review examines how plastic materials fragment into nanoplastics and potentially accumulate in the environment, with a focus on their possible impacts on human health. Researchers discuss how these tiny particles can enter the human body through ingestion, inhalation, and skin contact, and describe how they interact with cells at the molecular level. The study highlights that nanoplastics behave very differently from larger plastics due to their size and surface properties, raising concerns that warrant further investigation.
Unveiling the toxicity of micro-nanoplastics: A systematic exploration of understanding environmental and health implications
This review summarizes what is known about the toxicity of micro- and nanoplastics, noting they can cross critical barriers in the body including the blood-brain barrier. Studies in lab animals show these particles can cause DNA damage, oxidative stress, and cell death, with potential effects on the brain, heart, lungs, and skin, underscoring the need for more real-world human studies.
Biological Effects of Microplastics: A Review.
Researchers reviewed how microplastics harm a wide range of living things, finding they cause physical damage, inflammation, oxidative stress, and reproductive problems in aquatic animals, while also carrying toxic chemicals and dangerous bacteria into organisms. Major gaps remain in understanding the effects of long-term low-dose exposure and the risks posed by even tinier nanoplastics.
Ecotoxicological Impacts of Micro- and Nanoplastics in Terrestrial and Aquatic Environments
A broad review of ecotoxicological studies found that micro- and nanoplastics cause physical harm, oxidative stress, endocrine disruption, and reproductive impairment across a wide range of terrestrial and aquatic organisms, with nanoplastics generally exhibiting greater toxicity due to their smaller size and greater bioavailability.
Review of mechanisms and impacts of nanoplastic toxicity in aquatic organisms and potential impacts on human health
This review summarizes what we know about how nanoplastics (tiny plastic particles smaller than 1 micrometer) affect fish, shellfish, and other aquatic life, and what that could mean for people who eat seafood. Studies show nanoplastics build up in marine organisms and move up the food chain, causing oxidative stress, DNA damage, and inflammation along the way. Major gaps remain in understanding the long-term health effects of the low levels of nanoplastics people are likely exposed to through their diet.
Microplastic and nanoplastic transfer, accumulation, and toxicity in humans
Researchers reviewed human exposure routes to micro- and nanoplastics — via air, water, and food — and summarized reported toxicological outcomes, identifying ingestion and inhalation as primary entry points and flagging oxidative stress, inflammation, and endocrine disruption as key health concerns warranting further study.
Systemic effects of nanoplastics on multi-organ at the environmentally relevant dose: The insights in physiological, histological, and oxidative damages
Researchers gave mice nanoplastics at doses estimated to match real-world human exposure levels and found the particles crossed the intestinal barrier and accumulated in the liver and kidneys. Even at these low, environmentally relevant doses, the nanoplastics caused oxidative stress and tissue damage across multiple organs. The findings suggest that everyday nanoplastic exposure may pose broader health risks than previously assumed.