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Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Environmental Sources Human Health Effects Nanoplastics Sign in to save

Microplastic and nanoplastic transfer, accumulation, and toxicity in humans

Current Opinion in Toxicology 2021 72 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Phoebe A. Stapleton

Summary

Researchers reviewed human exposure routes to micro- and nanoplastics — via air, water, and food — and summarized reported toxicological outcomes, identifying ingestion and inhalation as primary entry points and flagging oxidative stress, inflammation, and endocrine disruption as key health concerns warranting further study.

Models

Plastics impact our daily lives. Unfortunately, it is the disuse and disposal of these items that may affect us the greatest. Plastic micro- and nanosized particles, likely from bulk degradation, have been identified in air pollution and water sources. Recently, plastic particles have also been identified in consumable products. The purpose of this review is to identify the likely routes of human exposure, the toxicological outcomes and concerns currently reported, and to provide some considerations for future assessments.

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