Papers

20 results
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Article Tier 2

Microplastics are a hotspot for antibiotic resistance genes: Progress and perspective

This review examines growing evidence that microplastics serve as hotspots for antibiotic resistance genes in the environment. Researchers found that microplastics selectively accumulate antibiotic-resistant bacteria and resistance genes on their surfaces across wastewater, aquatic, and terrestrial environments. The dense bacterial communities and concentrated pollutants on microplastic surfaces create favorable conditions for the spread and evolution of antibiotic resistance, raising concerns about potential risks to human health.

2021 The Science of The Total Environment 244 citations
Article Tier 2

Determining the Contribution of Micro/Nanoplastics to Antimicrobial Resistance: Challenges and Perspectives

This review examines how microplastics in the environment serve as surfaces where antibiotic-resistant bacteria can grow and exchange resistance genes, potentially worsening the global antimicrobial resistance crisis. Researchers found that the unique surface properties of micro- and nanoplastics create favorable conditions for the spread of antibiotic resistance genes among microorganisms. The study highlights that microplastic pollution and antibiotic resistance are interconnected environmental health challenges that may need to be addressed together.

2023 Environmental Science & Technology 64 citations
Article Tier 2

A review on the effect of micro- and nano-plastics pollution on the emergence of antimicrobial resistance

This review highlights how microplastics serve as breeding grounds for antimicrobial resistance genes, examining the overlooked interaction between plastic pollution and antibiotic resistance that poses combined threats to environmental and human health.

2022 Chemosphere 34 citations
Article Tier 2

Microplastics pollution in the ocean: Potential carrier of resistant bacteria and resistance genes

This review examined microplastics in marine environments as carriers of antibiotic-resistant bacteria and resistance genes, finding that plastic surfaces selectively enrich resistance genes through horizontal gene transfer and co-selection pressure, making ocean microplastics a vector for resistance dissemination across ecosystems.

2021 Environmental Pollution 96 citations
Article Tier 2

Selective enrichment of antibiotic resistome and bacterial pathogens by aquatic microplastics

This review found that microplastics in aquatic environments selectively enrich antibiotic-resistant bacteria, resistance genes, and bacterial pathogens in their biofilms, making plastic debris a potential vector for spreading antimicrobial resistance.

2022 Journal of Hazardous Materials Advances 27 citations
Article Tier 2

Selection for antimicrobial resistance in the plastisphere

This review examines how microplastics in the environment may contribute to the spread of antimicrobial resistance by providing surfaces where bacteria, antibiotics, and resistant genes converge. Researchers describe several mechanisms by which the microbial communities living on microplastics, known as the plastisphere, could accelerate horizontal gene transfer of resistance traits. The study highlights an emerging concern at the intersection of plastic pollution and the global antimicrobial resistance crisis.

2023 The Science of The Total Environment 24 citations
Article Tier 2

Microplastic-associated pathogens and antimicrobial resistance in environment

This review examines how microplastics in the environment act as surfaces for disease-causing bacteria and antibiotic-resistant microbes to colonize and spread. Researchers found that microplastics can carry pathogens and facilitate the transfer of antimicrobial resistance genes between bacteria in water systems. The findings raise concerns that microplastic pollution may be contributing to the growing global challenge of antibiotic resistance.

2021 Chemosphere 175 citations
Article Tier 2

Microplastics in fresh- and wastewater are potential contributors to antibiotic resistance - A minireview

Researchers reviewed the link between microplastic pollution and the spread of antibiotic resistance in freshwater environments, finding that microplastic surfaces host unique bacterial communities enriched in antibiotic-resistant bacteria and the resistance genes they can share with other microbes. The close packing of bacteria in these plastic-surface biofilms may accelerate the spread of drug-resistant pathogens through drinking water sources, though the full health implications remain poorly understood.

2022 Journal of Hazardous Materials Advances 31 citations
Article Tier 2

The interplay between antimicrobial resistance, heavy metal pollution, and the role of microplastics

This review explores the three-way connection between microplastics, heavy metals, and antibiotic resistance in the environment. Microplastics serve as surfaces where bacteria form biofilms and exchange resistance genes, while heavy metals have been driving bacterial resistance for billions of years through similar genetic mechanisms. Together, these pollutants create hotspots where dangerous antibiotic-resistant bacteria can develop and spread.

2025 Frontiers in Microbiology 39 citations
Article Tier 2

Environmental drivers of antibiotic resistance: Synergistic effects of climate change, co-pollutants, and microplastics

This review examines how climate change, chemical pollutants, and microplastics work together to accelerate the spread of antibiotic resistance, a growing global health crisis. Microplastics provide surfaces where bacteria form communities that exchange resistance genes, and as these plastics age in the environment, they become even better at absorbing other pollutants, creating hotspots that amplify drug resistance.

2025 Journal of Hazardous Materials Advances 15 citations
Article Tier 2

Microplastics as emerging reservoirs of antimicrobial resistance: Clinical relevance and environmental mechanisms

This review examines how microplastics act as environmental reservoirs for antibiotic resistance genes, creating selective microenvironments through antibiotic and metal adsorption, biofilm formation, and horizontal gene transfer, with potential pathways to clinical human exposure.

2025 Journal of Clinical and Experimental Investigations
Systematic Review Tier 1

The Plastisphere Resistome: A Systematic Review of Antibiotic Resistance Genes and Resistant Bacteria on Microplastics

This systematic review examines whether microplastic-associated biofilms harbor higher levels of antibiotic-resistant bacteria compared to surrounding environments. If microplastics act as hotspots for antibiotic resistance genes, they could spread drug-resistant bacteria through water systems, posing a serious concern for human health and the effectiveness of antibiotics.

2026 Open Science Framework
Article Tier 2

How microplastics and nanoplastics shape antibiotic resistance?

This review examines how micro- and nanoplastics act as vectors for antibiotic resistance genes, facilitating their spread through environmental and biological systems by creating selective pressure and hosting microbial communities that exchange resistance determinants.

2022 Water Emerging Contaminants & Nanoplastics 5 citations
Article Tier 2

Enrichment of Antibiotic Resistance Genes on Plastic Waste in Aquatic Ecosystems, Aquatic Animals, and Fishery Products

This review examines how plastic waste in water creates surfaces where antibiotic-resistant bacteria thrive and share resistance genes with each other. Microplastics in rivers, oceans, and fish farms were consistently found to harbor more antibiotic resistance genes than natural materials like rocks or sand. Since fish and shellfish can accumulate these microplastic-associated resistant bacteria, there is a risk that drug-resistant infections could reach humans through the seafood supply chain.

2025 Antibiotics 5 citations
Article Tier 2

Microplastics mediated antibiotic resistance gene enrichment and transfer in environment: Different types, microplastic antibiotic resistance gene ecological island and nano-size effect

This review examines how microplastics serve as platforms for accumulating and spreading antibiotic resistance genes in the environment. Researchers introduced the concept of a microplastic antibiotic resistance gene ecological island, describing how plastic surfaces create niches where resistant bacteria and mobile genetic elements concentrate. The study found that biodegradable and aged microplastics are particularly effective at promoting resistance gene adhesion and transfer, posing a dual environmental threat.

2026 Ecotoxicology and Environmental Safety
Article Tier 2

Microplastics and antibiotic resistance genes as rising threats: Their interaction represents an urgent environmental concern

This review examines how microplastics interact with antibiotics and antibiotic-resistant bacteria in the environment, creating a combined pollution threat. Microplastics can absorb antibiotics onto their surface and serve as platforms where bacteria exchange resistance genes. This interaction could accelerate the spread of antibiotic resistance, making infections harder to treat and posing a growing public health risk.

2025 Current Research in Microbial Sciences 6 citations
Article Tier 2

Interaction between microplastic biofilm formation and antibiotics: Effect of microplastic biofilm and its driving mechanisms on antibiotic resistance gene

This review explores how microplastics in water environments develop biofilms that interact with antibiotics in concerning ways. Researchers found that biofilm-coated microplastics can enhance the adsorption of antibiotics and serve as hotspots for antibiotic resistance genes. The study highlights the risk that microplastic biofilms could accelerate the spread of antibiotic resistance through aquatic ecosystems.

2023 Journal of Hazardous Materials 117 citations
Article Tier 2

The nexus of microplastics, food and antimicrobial resistance in the context of aquatic environment: Interdisciplinary linkages of pathways

This review examines how microplastics in aquatic environments serve as surfaces where bacteria can grow, share antibiotic resistance genes, and then enter the food chain through contaminated seafood. The combination of microplastic pollution and antimicrobial resistance creates a compounding threat, as resistant bacteria riding on plastic particles can survive water treatment and reach humans. The authors call for interdisciplinary research connecting environmental science and public health to address this growing risk.

2025 Journal of Contaminant Hydrology 7 citations
Article Tier 2

Interaction of Microplastics with Antibiotics in Aquatic Environment: Distribution, Adsorption, and Toxicity

This review examines how microplastics and antibiotics interact in waterways, finding that microplastics can absorb antibiotics from the water and change their availability and toxicity to aquatic organisms. Critically, microplastics also provide surfaces where antibiotic resistance genes can accumulate and spread among bacteria. This is concerning for human health because it means microplastics in water could be accelerating the spread of antibiotic-resistant infections.

2021 Environmental Science & Technology 415 citations
Article Tier 2

[Influencing Factors and Mechanisms of Antibiotic Resistance Gene Enrichment by Microplastics in the Environment].

This review examines how microplastics in the environment serve as carriers for antibiotic resistance genes, enriching and spreading resistant bacteria across air, soil, water, and sediments. Researchers found that the type, surface characteristics, and aging of microplastics all influence how effectively they accumulate resistance genes and facilitate horizontal gene transfer. The findings highlight the need to consider microplastics as an important vector in the environmental spread of antibiotic resistance.

2026 PubMed