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61,005 resultsShowing papers similar to Microbiome First Approaches to Rescue Public Health and Reduce Human Suffering
ClearMicroplastic emerging pollutants – impact on microbiological diversity, diarrhea, antibiotic resistance, and bioremediation
This review examines how global plastic waste accumulation affects microbial diversity, promotes diarrheal disease, and accelerates antibiotic resistance, while also surveying bioremediation strategies for managing microplastic pollution.
Impact of Cumulative Environmental and Dietary Xenobiotics on Human Microbiota: Risk Assessment for One Health
This review examines cumulative exposure to environmental and dietary xenobiotics including microplastics, pesticides, and food additives, assessing their combined impact on the human gut microbiome within a One Health risk framework.
Symbiotoxicity: The Ability of Environmental Stressors to Damage Healthy Microbiome Structure and Interactions with the Host
This review proposes the concept of symbiotoxicity to describe how environmental stressors including microplastics, chemicals, and pathogens can disrupt healthy host-microbiome interactions, arguing that damage to the microbiome should be considered a distinct endpoint in ecological risk assessment.
Improving the assessment of ecosystem and wildlife health: microbiome as an early indicator
Researchers reviewed evidence that the microbiome — the community of microorganisms living in environments and within animals — can serve as an early warning system for ecosystem disturbance, rapidly reflecting the impact of human activities before other signs of harm are visible.
Role of Microbes in Microplastic Removal and Its Effect on Human Health
This review examines the role of microbes in microplastic removal from environmental matrices and food systems, covering both degradation pathways and the health implications of microplastic-microbiome interactions for humans and other organisms.
The Hidden Cost of Cleanliness and Beauty: How the Microbiome Impacts Our Health and the Planet and Solutions through Green Chemistry and the Circular Economy
This review examines how personal care products and household cleansers affect the human microbiome, discussing evidence that antimicrobial ingredients disrupt skin and gut microbial communities in ways that may have long-term health consequences.
Gut microbiota: an ideal biomarker and intervention strategy for aging
Not relevant to microplastics — this review explores how gut microbiome composition can serve as a biomarker for aging and a target for anti-aging interventions in humans, without addressing plastic pollution.
Interactions between microplastics and microbiota in a One Health perspective
This review examines how microplastics interact with microbial communities across human, animal, and environmental settings using a One Health framework. Microplastics disrupt the normal balance of microbiota in the gut, soil, and water, and serve as surfaces where harmful bacteria and antibiotic resistance genes accumulate and spread. The authors argue that understanding these microplastic-microbe interactions across all domains of life is essential for protecting both ecosystem and human health.
Resilience to Global Health Challenges Through Nutritional Gut Microbiome Modulation
This review explores how gut microbiome composition during early life influences long-term health, and how nutritional strategies can help build resilience against chronic diseases. Researchers highlight that environmental factors including microplastics and other contaminants can disrupt the developing gut microbiome, potentially contributing to allergies, obesity, and neurological conditions. The study suggests that targeted nutritional interventions to support healthy gut bacteria could help counteract some of these environmental exposures.
Microbial risks associated with microplastics in the food chain and possible control measures (literature review). Part 1. Dietary intake and influence on the gut microbiota
This review summarizes evidence that microplastics commonly found in food and drinking water can disrupt the human gut microbiome when ingested. Studies show that microplastics alter the composition and function of intestinal bacteria, potentially affecting digestion, immunity, and overall health. Since a healthy gut microbiome is essential for human wellbeing, this pathway of harm deserves attention alongside other known risks of microplastic exposure.
Microplastics and human health: unveiling the gut microbiome disruption and chronic disease risks
This review summarizes evidence that microplastics disrupt the gut microbiome, the community of bacteria in our digestive system that plays a key role in immunity, metabolism, and overall health. By altering gut bacteria balance and triggering inflammation, microplastic exposure may contribute to chronic conditions including inflammatory bowel disease, metabolic disorders, and potentially even neurological problems through the gut-brain connection.
Microplastics and the gut microbiome: Emerging health concerns and strategies
This review covers how microplastic ingestion affects the gut microbiome, describing mechanisms by which microplastics cause intestinal disorders, disrupt endocrine function, and promote pathogenic bacterial growth, while also noting inhalation and dermal absorption as secondary exposure routes.
Impacts of microplastics on ecosystem services and their microbial degradation: a systematic review of the recent state of the art and future prospects
This systematic review summarized microplastic distribution across water, soil, food, and air and cataloged reported health effects including digestive illness, respiratory disorders, sleep disturbances, obesity, diabetes, and cancer following exposure. It highlighted microbial degradation strategies including biofilms and genetically modified microorganisms as promising approaches for environmental microplastic remediation.
Polybiome Systems Medicine: Conceptual Architecture, Methodological Foundations, and Translational Applications — Volume I: Vision and Foundational Methodology
This foundational document presents the Polybiome Systems Medicine framework, proposing that the human organism is a co-constructed biological consortium shaped by host genomics, multi-kingdom microbiomes, environmental exposures, and immune networks. The framework incorporates environmental factors including microplastics and endocrine disruptors as modulators of human health. The authors outline a five-layer architecture designed to integrate diverse biological data for a more holistic approach to medicine.
The microplastic-crisis: Role of bacteria in fighting microplastic-effects in the digestive system
This review examines how microplastics affect the human digestive system and explores whether certain bacteria could help counteract the damage. Microplastics disrupt the gut by altering microbial communities, interfering with digestive enzymes, and damaging the protective mucus lining. The authors highlight the potential for probiotic bacteria to bind to microplastics, reduce inflammation, and help repair the gut environment, offering a possible protective strategy against microplastic-related digestive harm.
Health implications of microplastic exposure and sustainable solutions
This review explores the various pathways by which microplastics contaminate aquatic and terrestrial ecosystems through human activities, and how they accumulate in the food chain. Researchers summarize the health implications of microplastic exposure through mechanisms like oxidative stress, gut microbiome disruption, and inflammation. The study emphasizes the need for standardized detection methods and stronger regulatory frameworks to address microplastic contamination in the human food supply.
Probiotics an emerging therapeutic approach towards gut-brain-axis oriented chronic health issues induced by microplastics: A comprehensive review
This review examines how microplastics disrupt the gut-brain axis, the communication system between the digestive system and the brain, leading to chronic health problems like inflammation and neurological issues. The authors highlight probiotics as a promising treatment approach, since beneficial bacteria can help repair gut damage caused by microplastic exposure. The findings suggest that supporting gut health through probiotics may help counteract some of the harmful effects of microplastics on both digestion and brain function.
Relevance of gut microbiome research in food safety assessment
This review examines evidence that food additives and microplastics may disrupt the gut microbiome and, in turn, affect human health. The researchers discuss how these non-nutritive dietary compounds can alter gut bacterial communities through mechanisms that are often overlooked in food safety evaluations. They recommend integrating gut microbiome science into food risk assessment frameworks to better protect human health.
Impact of microplastics on the intestinal microbiota: A systematic review of preclinical evidence
Across 28 preclinical studies, microplastics triggered intestinal dysbiosis characterized by increased Firmicutes and Proteobacteria and decreased Bacteroidetes, while increasing gut permeability and elevating pro-inflammatory cytokines including IL-1β, TNF-α, and IL-6.
Planetary health and non-communicable diseases—A converging global crisis
This review examines the convergence of environmental degradation and the global rise in non-communicable diseases, identifying microplastics as one of several environmental pollutants contributing to cardiovascular disease, diabetes, cancer, and chronic respiratory conditions. The authors argue that addressing plastic pollution is integral to a planetary health approach to disease prevention.
Microplastics on the frontline: causes, strategies to combat pollution and protect health with advanced bioremediation—a review
This systematic review examines how microplastics carry toxic chemicals like heavy metals and persistent pollutants into the food chain, ultimately reaching humans. It also explores promising bioremediation approaches — using bacteria and enzymes to break down microplastics — as a potential strategy to reduce exposure.
Micro- and Nanoplastics as Emerging Environmental Materials: GreenChemistry Insights into Gut Microbiota Disruption and Chronic DiseasePathways
Researchers reviewed how micro- and nanoplastics accumulate in the gastrointestinal tract and disrupt gut microbiota composition, finding evidence linking these exposures to reduced microbial diversity, gut barrier dysfunction, systemic inflammation, and potential contributions to chronic diseases including metabolic disorders and neurodegeneration.
Microbiome: A forgotten target of environmental micro(nano)plastics?
This review examines how micro- and nanoplastics affect the microbiome of various organisms, an area that has received less attention than other toxicological endpoints. Researchers found that most studies focused on polystyrene particles and that exposure consistently disrupted microbiome composition, triggered immune responses, and altered enzyme activity across organisms including crustaceans, fish, and mammals. The study highlights the microbiome as an important but often overlooked target of microplastic pollution.
Food, Agriculture, Environment and Chronic non-communicable diseases: How are they connected?
This review examined the connections between modern diet, agricultural practices, and the rise of chronic non-communicable diseases, arguing that environmental changes since industrialization — including chemical pollutants, microplastics, and nutrient-depleted food systems — have outpaced evolutionary adaptation. The authors called for a food systems approach to reducing chronic disease burden.