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61,005 resultsShowing papers similar to Mimicking human ingestion of microplastics: Oral bioaccessibility tests of bisphenol A and phthalate esters under fed and fasted states
ClearMetada on human bioaccessibility of phthalates and bisphenol A from microplastics
This entry provides metadata linking to a study by Lopez-Vazquez et al. that investigated the oral bioaccessibility of bisphenol A and phthalate esters leaching from microplastics under simulated fed and fasted gastrointestinal conditions, finding that digestive state significantly influenced the release of these chemical additives.
Metada on human bioaccessibility of phthalates and bisphenol A from microplastics
This entry provides metadata linking to a study by Lopez-Vazquez et al. that investigated the oral bioaccessibility of bisphenol A and phthalate esters leaching from microplastics under simulated fed and fasted gastrointestinal conditions, finding that digestive state significantly influenced the release of these chemical additives.
Exploring the release of microplastics' additives in the human digestive environment by an in vitro dialysis approach using simulated fluids
Researchers used an in vitro dialysis method with simulated digestive fluids to simultaneously assess both the bioaccessibility and bioavailability of plastic additives released from microplastics during human digestion. The study found that biopolymer microplastics released approximately four times more additives than conventional petroleum-based plastics, and that mechanical recycling and marine aging altered additive release patterns, raising questions about the safety assumptions around biodegradable plastics.
Desorption of bisphenol A from microplastics under simulated gastrointestinal conditions
Researchers investigated bisphenol A desorption from three types of microplastics under simulated gastrointestinal conditions, finding that ingested microplastics can release adsorbed BPA during digestion, posing potential health risks.
An automatic flow-through system for exploration of the human bioaccessibility of endocrine disrupting compounds from microplastics
An automated flow-through system was developed to investigate the bioaccessibility of plastic-borne contaminants in the human gastrointestinal tract using physiologically relevant body fluids. The system measured leaching rates of plastic additives under fasted and fed state conditions, providing the first mechanistic data on how ingested microplastics release chemical contaminants in the human gut.
Bioaccessibility of plastic-related compounds from polymeric particles in marine settings: Are microplastics the principal vector of phthalate ester congeners and bisphenol A towards marine vertebrates?
Researchers studied whether microplastics are a major pathway for delivering harmful plastic chemicals like phthalates and bisphenol A to marine animals during digestion. They found that while microplastics do release these compounds under simulated gut conditions, the amounts were relatively low compared to other environmental sources. The study suggests that microplastics may not be the primary route of chemical exposure for marine vertebrates, though they still contribute to the overall burden.
Processes influencing the toxicity of microplastics ingested through the diet
This study investigated what happens to chemical additives in microplastics when the plastics go through cooking and human digestion. Researchers found that both culinary processes and gastrointestinal conditions caused plastics to release potentially harmful chemicals, including phthalates and bisphenol A, suggesting that microplastics in food may be a meaningful route for chemical exposure in people.
Exposure to microplastic associated chemicals upon oral consumption of microplastics
This thesis quantified the release of plastic-associated chemical contaminants from microplastics during simulated human digestion, measuring how much of these chemicals actually leach out under stomach and intestinal conditions. The research helps estimate the chemical exposure humans receive when they ingest microplastics through food and water.
Bioaccessibility of microplastic-associated heavy metals using an in vitro digestion model and its implications for human health risk assessment
Researchers evaluated the bioaccessibility of heavy metals associated with microplastics using an in vitro digestion model to assess human health risks. The study found significant adsorption of arsenic, chromium, cadmium, and lead onto polyvinyl chloride microplastics, with varying bioaccessibility across different digestive phases. The findings suggest that incorporating bioaccessibility data into risk assessments may provide more accurate estimates of health risks from ingesting microplastic-associated heavy metals.
Release of additives and non-intentionally added substances from microplastics under environmentally relevant conditions
Researchers measured how chemical additives leach out of different types of microplastics under realistic environmental conditions and found wildly different release rates — spanning five orders of magnitude over 64 days — highlighting that the type of plastic matters greatly when assessing the chemical risks microplastics pose to ecosystems.
How Digestive Processes Can Affect the Bioavailability of PCBs Associated with Microplastics: A Modeling Study Supported by Empirical Data
Researchers used a simulated human digestive model to study whether gut processes change how quickly chemicals like PCBs transfer on and off microplastic particles. They found that digestive enzymes and bile salts significantly accelerated the release of these chemicals from microplastics, suggesting that the human gut environment may increase exposure to plastic-associated pollutants. The study provides new evidence that microplastics could act as carriers that release harmful chemicals more readily during digestion.
Leaching of PBDEs from microplastics under simulated gut conditions: Chemical diffusion and bioaccumulation
This study examined how polybrominated diphenyl ethers (PBDEs) leach from microplastics under simulated gut conditions, finding that chemical diffusion rates were strongly influenced by gut fluid composition and that hydrophobic contaminants could transfer to organisms at levels posing potential bioaccumulation risks.
Investigating the desorption of polybrominated diphenyl ethers from polyethylene microplastics to sediment
Researchers investigated how polybrominated diphenyl ethers (PBDEs) desorb from polyethylene microplastics under simulated gut conditions, finding that digestive fluids with surfactants significantly enhanced PBDE release, raising concerns about gut-mediated transfer of flame retardants from ingested plastic particles.
In vitro digestion of microplastics in human digestive system: Insights into particle morphological changes and chemical leaching
Researchers simulated human digestion on four common types of microplastics and found that stomach acid and digestive enzymes changed the particles' shape, surface texture, and caused them to release chemical additives. The study shows that microplastics are not inert once swallowed -- they are actively transformed in the gut, which could increase their ability to interact with intestinal tissues and release potentially harmful chemicals.
Leaching of polybrominated diphenyl ethers from microplastics in fish oil: Kinetics and bioaccumulation
The leaching kinetics of polybrominated diphenyl ethers (PBDEs) from microplastics into fish oil were characterized to estimate chemical transfer to organism tissues upon ingestion. Leaching rates were contaminant- and polymer-dependent, providing mechanistic data for assessing how ingested microplastics increase exposure to inherent flame retardant additives.
Measuring the Effect of Dietary Microplastic on Biomagnification Potential of Environmental Contaminants and Plastic Additives
Researchers measured the effect of dietary microplastic ingestion on the biomagnification potential of hydrophobic organic contaminants and plastic additives in the gastrointestinal tract, testing competing hypotheses about whether microplastics increase, decrease, or negligibly affect contaminant uptake.
Plasticiser leaching from polyvinyl chloride microplastics and the implications for environmental risk assessment
Researchers measured the leaching of diethylhexyl phthalate (DEHP) and bisphenol A (BPA) from polyvinyl chloride microplastics under simulated marine conditions, finding that both plasticizers leached in a concentration- and time-dependent manner. These findings are important for environmental risk assessments of PVC microplastics, which represent a major fraction of ocean plastic pollution.
Microplastics emerge as a hotspot for dibutyl phthalate sources in rivers and oceans: Leaching behavior and potential risks
Researchers investigated how the plasticizer dibutyl phthalate leaches from PVC microplastics in both freshwater and seawater environments. They found that UV irradiation and water chemistry significantly influenced leaching rates, with higher release observed under simulated environmental conditions. The findings suggest that microplastics in rivers and oceans act as ongoing sources of potentially harmful chemical additives.
Sorption and release process of polybrominated diphenyl ethers (PBDEs) from different composition microplastics in aqueous medium: Solubility parameter approach
This study investigated how four common microplastic types (PET, PP, LDPE, and PS) sorb and release flame retardant chemicals called polybrominated diphenyl ethers (PBDEs). The type of plastic polymer significantly affects how much of these toxic chemicals it retains, with implications for how much is released when microplastics are ingested by organisms.
Bioaccessibility of Trace Metals and Rare Earth Elements (REE) in Microplastic
Researchers measured the bioaccessibility of trace metals and rare earth elements adsorbed onto beach microplastics using simulated digestive fluid conditions. Metals were released from microplastic surfaces under stomach acid conditions, indicating that plastic ingestion can deliver these contaminants to digestive systems of marine organisms and humans.
Is bisphenol A sorbed onto microplastics less bioavailable than freely dissolved bisphenol A? Implications for the gut health in a murine model
Using an in vivo rat model, researchers tested whether bisphenol A adsorbed onto microplastics is less bioavailable in the gastrointestinal tract than freely dissolved BPA, finding that plastic-bound BPA showed altered absorption kinetics and different hormonal effects than dissolved BPA.
Consequential fate of bisphenol-attached PVC microplastics in water and simulated intestinal fluids
Researchers tested how bisphenol-attached PVC microplastics release bisphenols in aquatic and simulated intestinal fluid environments, finding that desorption was faster under gut-like conditions and that released bisphenols were cytotoxic to human intestinal cell lines.
Dibutyl phthalate release from polyvinyl chloride microplastics: Influence of plastic properties and environmental factors
Researchers investigated how dibutyl phthalate leaches from PVC microplastics into surrounding environments, finding that particle size, temperature, pH, and salinity all significantly influenced the release rate of this plasticizer additive.
Leaching kinetics and bioaccumulation potential of additive-derived organophosphate esters in microplastics
Researchers studied the leaching kinetics of organophosphate ester additives from microplastics in aquatic environments, finding that these flame retardants and plasticizers are released at rates that depend on temperature and water chemistry, with implications for bioaccumulation in aquatic organisms.