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Consequential fate of bisphenol-attached PVC microplastics in water and simulated intestinal fluids

Environmental Science and Ecotechnology 2020 78 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 50 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Pengfei Wu, Pengfei Wu, Pengfei Wu, Pengfei Wu, Zongwei Cai Pengfei Wu, Pengfei Wu, Pengfei Wu, Pengfei Wu, Pengfei Wu, Pengfei Wu, Pengfei Wu, Yuanyuan Tang, Zongwei Cai Yuanyuan Tang, Yuanyuan Tang, Zongwei Cai Yuanyuan Tang, Yuanyuan Tang, Zongwei Cai Yuanyuan Tang, Yuanyuan Tang, Pengfei Wu, Pengfei Wu, Pengfei Wu, Hangbiao Jin, Hangbiao Jin, Hangbiao Jin, Hangbiao Jin, Hangbiao Jin, Yuanyuan Tang, Zongwei Cai Yuanyuan Tang, Yuanyuan Tang, Yuanyuan Tang, Yuanyuan Tang, Yuanyuan Tang, Pengfei Wu, Pengfei Wu, Zongwei Cai Zongwei Cai Yuanyuan Song, Zongwei Cai Yuanyuan Tang, Yunsong Liu, Hangbiao Jin, Yuanyuan Song, Hangbiao Jin, Hangbiao Jin, Pengfei Wu, Hangbiao Jin, Hangbiao Jin, Hangbiao Jin, Zongwei Cai Hangbiao Jin, Yuanyuan Tang, Hangbiao Jin, Yuanyuan Tang, Zongwei Cai Hangbiao Jin, Zongwei Cai Pengfei Wu, Pengfei Wu, Zongwei Cai Zongwei Cai Zongwei Cai Zongwei Cai Zongwei Cai Zongwei Cai Zongwei Cai Zongwei Cai Zongwei Cai Yuanyuan Tang, Yuanyuan Tang, Hangbiao Jin, Hangbiao Jin, Yunsong Liu, Pengfei Wu, Yuanyuan Tang, Yuanyuan Tang, Pengfei Wu, Yuanyuan Tang, Yuanyuan Tang, Yuanyuan Tang, Yuanyuan Tang, Zongwei Cai Yuanyuan Tang, Pengfei Wu, Zongwei Cai Zongwei Cai Zongwei Cai Zongwei Cai Hangbiao Jin, Yuanyuan Tang, Zongwei Cai Zongwei Cai Yuanyuan Tang, Zongwei Cai Zongwei Cai Zongwei Cai Yuanyuan Tang, Zongwei Cai Zongwei Cai Yuanyuan Tang, Zongwei Cai

Summary

Researchers tested how bisphenol-attached PVC microplastics release bisphenols in aquatic and simulated intestinal fluid environments, finding that desorption was faster under gut-like conditions and that released bisphenols were cytotoxic to human intestinal cell lines.

Polymers

The ever-increasing prevalence of microplastics and different bisphenols made the presence of bisphenol-attached microplastics a critical concern. In this study, experiments were performed to examine desorption behaviors and cytotoxicity performance of contaminated microplastics in aquatic surroundings and intestinal environment after ingestion by organisms (cold-/warm-blooded). The kinetic study shows that the rate of desorption for bisphenols can be enhanced threefold under simulated warm intestinal conditions. The Freundlich isotherms indicate multiple-layer desorption of the bisphenols on the heterogeneous surfaces of polyvinyl chloride (PVC) microplastics. Hysteresis was detected in the adsorption/desorption of bisphenols in a water environment, but no adsorption/desorption hysteresis was observed in the simulated intestinal conditions of warm-blooded organisms. Due to enhanced bioaccessibility, the desorption results imply that the environmental risk of contaminated PVC microplastics may be significantly increased after ingestion at a high bisphenols dosage. Although with different IC<sub>50</sub>, the five bisphenols released under the intestinal conditions of warm-blooded organisms can cause higher proliferation reduction in fish and human cell lines than the bisphenols released in water. This study helps elucidate the consequential fate and potential cytotoxicity of contaminated microplastics and the possible implications of the microplastics as a critical vector for bisphenols to increase the potential health risks.

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