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20 resultsShowing papers similar to Plasticisers: A Potential Reproductive-toxicant for Humans
ClearComprehensive Insight from Phthalates Occurrence: From Health Outcomes to Emerging Analytical Approaches
This review summarizes the widespread occurrence of phthalates, chemicals commonly used as plasticizers in plastic products, and their potential health effects including endocrine disruption and reproductive harm. The study also surveys emerging analytical methods for detecting phthalates in food, water, and biological samples, highlighting the challenge of daily human exposure through consumer products.
Phthalates and Their Impacts on Human Health
This review examines phthalates, chemicals widely used to make plastics flexible, and their harmful effects on human health as endocrine disruptors. Chronic exposure to phthalates has been linked to reproductive problems, developmental issues in children, and complications during pregnancy. Since phthalates are common additives in microplastics, understanding their toxicity is essential for assessing the full health risk of microplastic exposure.
Unveiling the Hidden Dangers of Plasticizers: A Call for Immediate Action
This review highlights the hidden health dangers of plasticizers -- chemicals added to plastics found in food containers, toys, cosmetics, and personal care items -- calling for immediate regulatory action given their widespread human exposure and evidence of endocrine disruption and other toxic effects.
Impact of environmental toxin exposure on male fertility potential
This review examines how environmental toxin exposures, including endocrine-disrupting chemicals found in plastics, may contribute to declining male fertility. Researchers found consistent evidence linking exposure to phthalates, bisphenol A, and other synthetic chemicals to reduced sperm quality and hormonal disruption. The study suggests that the dramatic increase in human chemical exposures over recent decades may be a significant factor in the observed decline in male reproductive health.
Plastic and its Side Effects on Humans – A Review Article
This review examines the widespread use of plastics in daily life and their harmful side effects on human health, including the release of toxic chemicals like BPA and phthalates that act as endocrine disruptors and contribute to various diseases.
"Unseen Dangers: The Effects of Micro- and Nanoplastics on Human Reproductive Health - A Narrative Review"
This review examines the effects of micro- and nanoplastics on human reproductive health, covering evidence from in vitro, animal, and epidemiological studies showing that plastic particles can disrupt hormone signaling, sperm function, ovarian development, and placental integrity.
Advances in understanding the reproductive toxicity of endocrine-disrupting chemicals in women
This review examines how endocrine-disrupting chemicals such as bisphenol A, phthalates, and triclosan may interfere with the female reproductive system. Evidence indicates that these chemicals, found widely in the environment, can disrupt hormone function and may contribute to adverse reproductive outcomes, though the precise mechanisms are still being studied.
Implications of plastic-derived endocrine disruptors on human health
This review summarizes how chemicals released from plastics, known as endocrine disruptors, can interfere with the body's hormone systems. Common substances like BPA and phthalates mimic or block hormones, contributing to obesity, diabetes, reproductive problems, and developmental issues in children. Micro- and nanoplastics make the problem worse because they can release these hormone-disrupting chemicals inside the body after being ingested or inhaled.
Plastics and its effect to women reproductive systems
This article reviews how plastic pollution, including microplastics and the hormone-disrupting chemicals they contain, may affect women's reproductive health. It connects widespread plastic use to endocrine disruption, menstrual irregularities, and fertility concerns, though much of the evidence comes from laboratory and animal studies.
Micro- and Nanoplastics as Disruptors of the Endocrine System—A Review of the Threats and Consequences Associated with Plastic Exposure
This review summarizes how micro- and nanoplastics carry endocrine-disrupting chemicals that interfere with hormones controlling reproduction, thyroid function, metabolism, and brain development. The reproductive system is especially vulnerable, with studies showing that plastic particle exposure can cause oxidative stress, cell death, and infertility, raising serious concerns given how widespread these particles are in food and the environment.
Consequences of Exposure to Phthalates, Micro Plastics and Nano-plastics on the Organisms
This review summarizes the toxic effects of microplastics, polystyrene, and phthalate plasticizers (BPA, DBP, DEHP) on vertebrates and invertebrates. These chemicals enter organisms through food, water, and air, causing hormonal disruption, reproductive harm, and other health effects across a wide range of species.
Environmental and health hazards of chemicals in plastic polymers and products
Researchers reviewed the environmental and health hazards of chemicals in plastic polymers and products, examining the toxicological profiles of monomers, additives, and degradation products that can leach from plastics into food, water, and the environment. The study identifies numerous plastic-associated chemicals with endocrine-disrupting, carcinogenic, or developmental toxicity potential and calls for more comprehensive safety testing of plastic formulations.
Toxicological effects of micro/nano-plastics on human reproductive health: A review
This review summarizes research on how micro- and nanoplastics affect human reproductive health in both men and women. Evidence from animal and lab studies shows that these particles can accumulate in reproductive organs, disrupt hormones, damage eggs and sperm, and cause inflammation and oxidative stress. While human studies are still limited, the growing body of evidence suggests that microplastic exposure is a potential threat to fertility that warrants further investigation.
The Impact of Endocrine Disruptions on Animal and Human Organism
This review examines how endocrine-disrupting chemicals, including bisphenol A, phthalates, and micro- and nanoplastics, interfere with hormonal balance in animals and humans. Researchers describe how these substances interact with hormone receptors, induce epigenetic changes, and disrupt cell signaling pathways affecting reproduction, metabolism, and neurological function. The study highlights that nanoparticles, including microplastics, may amplify endocrine disruption and calls for more research into the molecular pathways involved.
Impact of Chemical Endocrine Disruptors and Hormone Modulators on the Endocrine System
This review examines how endocrine-disrupting chemicals, including those found in plastics, interfere with the body's hormone systems through both direct and indirect pathways. Researchers found that long-term exposure to these substances can affect reproductive health, metabolism, and development, with physical stressors like light and temperature also playing a role. The study highlights the complexity of endocrine disruption and the need for broader research into non-chemical factors as well.
Microplastic pollution-A major health problem-An update
This review summarizes the current understanding of microplastic pollution as a health concern, covering how these tiny plastic particles enter the human body through inhalation and ingestion of contaminated food and beverages. The study discusses chemical additives found in plastics, including endocrine disruptors like bisphenol A and phthalates, which have been associated with various health effects. However, the authors note that the fate and effects of microplastics once inside the human body remain controversial and require further study.
The widely disregarded health risks posed by phthalates - A global call for action
This review highlights the widespread health risks posed by phthalates from microplastic-containing products, emphasizing their routes of human exposure through food, packaging, and personal care items, and their documented effects including oncogenicity and fetal developmental impacts. The authors call for urgent global regulatory action given the scale and severity of phthalate exposure.
Solving the impact of Phthalate plasticizers in relieving environment pollution
This review examines how phthalate plasticizers—particularly DEHP, DEP, and DBP found in food packaging and cosmetics—enter soil and human bodies, where they disrupt metabolic and reproductive systems and contribute to environmental plastic pollution.
Microplastics exposure: implications for human fertility, pregnancy and child health
This review examines growing evidence that microplastics accumulate in the human placenta and may affect pregnancy outcomes and child development. Given that exposure during pregnancy can program lifelong health in offspring, the presence of these tiny plastic particles in reproductive tissues raises important concerns about fertility, pregnancy complications, and children's health.
Understanding the impact of nanoplastics on reproductive health: Exposure pathways, mechanisms, and implications
This review summarizes existing research on how nanoplastics (tiny plastic particles smaller than one micrometer) affect reproductive health in animals and potentially humans. Studies show that nanoplastics can accumulate in reproductive organs including the placenta, and evidence from animal studies links exposure to hormone disruption, reduced fertility, and developmental problems. The authors highlight a significant knowledge gap about nanoplastic effects on human reproduction, despite growing evidence that these particles reach our reproductive systems.