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The Impact of Endocrine Disruptions on Animal and Human Organism
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This review examines how endocrine-disrupting chemicals, including bisphenol A, phthalates, and micro- and nanoplastics, interfere with hormonal balance in animals and humans. Researchers describe how these substances interact with hormone receptors, induce epigenetic changes, and disrupt cell signaling pathways affecting reproduction, metabolism, and neurological function. The study highlights that nanoparticles, including microplastics, may amplify endocrine disruption and calls for more research into the molecular pathways involved.
Endocrine disruptors (EDCs) are chemicals that interfere with hormonal balance in both animals and humans, potentially leading to a wide range of health problems. This review explores how endocrine disruptors function, their sources, and their effects on human and animal health, including their impact on the reproductive system, metabolism, neuroendocrine function, and cancer progression. The aim of this review is to describe the mechanisms of action of endocrine disruptors, such as their interactions with hormonal receptors, induction of epigenetic changes, and effects on cell signaling pathways. Additionally, this work examines how endocrine disruptors influence physiological processes, evaluates the impact of nanoparticles on endocrine disruption, and discusses the body's defense mechanisms against these agents. Among the most well-known EDCs are bisphenol A (BPA) and phthalates, which have been linked to a wide range of health conditions. Recent studies have also highlighted the risks posed by nanoparticles, including microplastics and nanoplastics, which amplify endocrine disruption and disturb hormonal balance. Future research should focus on identifying molecular pathways affected by EDCs to mitigate their negative impact on the endocrine system.
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A review of the endocrine disrupting effects of micro and nano plastic and their associated chemicals in mammals
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This review summarizes how micro- and nanoplastics carry hormone-disrupting chemicals that can interfere with the thyroid, reproductive organs, and other parts of the endocrine system in mammals. Because these chemicals are not tightly bound to the plastic, they can leach into milk, water, and food, potentially disrupting hormone function in humans who consume them.
Implications of plastic-derived endocrine disruptors on human health
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This review summarizes how chemicals released from plastics, known as endocrine disruptors, can interfere with the body's hormone systems. Common substances like BPA and phthalates mimic or block hormones, contributing to obesity, diabetes, reproductive problems, and developmental issues in children. Micro- and nanoplastics make the problem worse because they can release these hormone-disrupting chemicals inside the body after being ingested or inhaled.
Microplastics as Emerging Contaminants: Investigating their Potential to Alter Human Metabolic and Endocrine Systems
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This review investigated the potential of microplastics to alter human hormone signaling, synthesizing evidence that plastic particles and their chemical additives can act as endocrine disruptors at environmentally relevant concentrations. The paper highlighted reproductive and metabolic pathways as areas of particular concern.
Nano and microplastics: unveiling their profound impact on endocrine health
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This review summarizes existing research showing that micro- and nanoplastics can disrupt the endocrine (hormone) system, altering reproductive hormones, thyroid function, and gene expression in lab and animal studies. Exposure to these particles triggered inflammation markers and oxidative stress in hormone-producing organs, suggesting that widespread plastic pollution may be contributing to rising rates of hormonal and reproductive health problems.
The Impact of Microplastics and Nanoplastics on Human Health: A Follow-Up Study Focusing on Endocrine, Nervous, and Immune Systems
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This review examines evidence for microplastic and nanoplastic impacts on the endocrine, nervous, and immune systems, documenting how particles detected in human organs can disrupt hormone signaling, induce neuroinflammation, and alter immune function.
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When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.