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61,005 resultsShowing papers similar to Environmental Chemicals: Integrative Approach to Human Biomonitoring and Health Effects
ClearIntegrative Biochemical Diagnostics: From Prenatal Genomics to Environmental and Behavioral Biomarkers
This short review proposes an integrative diagnostic framework linking advances in prenatal genomics, metabolic biomarkers, and environmental sensing, including detection of microplastics and endocrine-disrupting chemicals as emerging biomarkers of health risk.
Exposure and Health Effects of Microplastics in Humans
This doctoral thesis investigates exposure levels and health effects of microplastics in humans, synthesizing analytical chemistry and toxicological evidence on microplastic presence in human tissues and their potential biological impacts.
Integrative Biochemical Diagnostics: From Prenatal Genomics to Environmental and Behavioral Biomarkers
This short review proposes an integrative diagnostic framework linking advances in prenatal genomics, metabolic biomarkers, and environmental sensing, including detection of microplastics and endocrine-disrupting chemicals as emerging biomarkers of health risk.
Integrative Biochemical Diagnostics: From Prenatal Genomics to Environmental and Behavioral Biomarkers
This short review proposes an integrative diagnostic framework linking advances in prenatal genomics, metabolic biomarkers, and environmental sensing, including detection of microplastics and endocrine-disrupting chemicals as emerging biomarkers of health risk.
A review of environmental metabolism disrupting chemicals and effect biomarkers associating disease risks: Where exposomics meets metabolomics
This review examines how environmental chemicals, including contaminants associated with plastics, can disrupt human metabolism and contribute to conditions like obesity and diabetes. Researchers mapped the connections between chemical exposure and changes in metabolic biomarkers that signal disease risk. The study highlights the emerging field of metabolism-disrupting chemicals and the importance of understanding how everyday environmental exposures influence long-term metabolic health.
Workshop Report HBM4EU
This workshop report describes discussions among Nordic scientists and regulators about setting priorities for human biomonitoring of chemical exposures, including substances associated with plastic products. The meeting aimed to improve coordination between scientific research and regulatory use of biomonitoring data for chemical risk management.
Microplastics as an emerging threat to human health: Challenges and advancements in their detection
This review examined microplastics as an emerging threat to human health, highlighting their endocrine-disrupting properties, ability to accumulate pollutants, and the analytical challenges in accurately detecting and characterizing them across environmental and biological samples.
Microplastic Exposure and Human Health: Advancing Risk Assessment and Future Research Directions
This review synthesizes recent evidence that microplastics are present in human blood, respiratory tissue, placenta, and gut, examines proposed toxicological mechanisms, and identifies priorities for improving risk assessment frameworks and exposure measurement methods.
An integrated approach to assess exposure and early health effects in human populations exposed to micro- and nanoplastics
This paper outlines a proposed framework for systematically assessing human exposure to micro- and nanoplastics and their early health effects, noting that current estimates are hindered by a lack of standardized detection methods. Researchers emphasize that occupational settings where plastics are processed, as well as vulnerable populations like children and pregnant women, should be prioritized for study. The study calls for validated biomarkers and standardized protocols to better understand the real-world health consequences of human microplastic exposure.
Analytical methodology for unveiling human exposure to (micro)plastic additives
Researchers reviewed laboratory and population-level methods for measuring human exposure to chemicals that leach from plastics — such as bisphenols and flame retardants — detailing how these toxic additives can be tracked through urine and blood tests after entering the body.
Micro(nano)plastics, an emerging health problem
This review frames micro- and nanoplastics as an emerging human health problem, synthesizing evidence of exposure routes, organ-level accumulation, and biological effects, and calling for updated regulatory frameworks to address this novel class of environmental contaminants.
Umbrella Review: Impact of plastic-associated chemical exposure on human health.
This umbrella review pools evidence from multiple systematic reviews to assess how chemicals associated with plastics affect human health. The research examines exposure to plastic-related chemicals through food, water, air, and consumer products. This is one of the most comprehensive looks at the health impacts of plastic chemical exposure, covering effects that range from hormonal disruption to developmental concerns.
Multiple Effects, Pathways, and Potential Health Risks from Environmental Microplastic Exposure
This review synthesizes nearly two decades of research on the multiple pathways through which environmental microplastics affect human and ecological health, including chemical toxicity, physical impacts, and potential roles as carriers of pathogens and contaminants.
Analytical challenges in human exposome analysis with focus on environmental analysis combined with metabolomics
This review examined the analytical challenges of characterizing the human chemical exposome, covering sampling, sample preparation, and compound identification hurdles that currently limit our ability to link specific environmental chemical exposures to chronic disease outcomes.
Microplastic exposure and human health: an integrative toxicological perspective
This review takes an integrative toxicological perspective on how microplastic exposure may affect human health, examining exposure routes through food, water, and air. Researchers summarize evidence that microplastics' small size, durability, and surface reactivity enable them to adsorb heavy metals, form biofilms, and enter food chains. The study highlights that while evidence of harm is growing, significant gaps remain in understanding the long-term health implications of chronic microplastic exposure.
Plastics, microplastics, and human contamination: A literature review
This literature review synthesizes research on human contamination by plastics and microplastics, covering ingestion, inhalation, and dermal exposure routes and summarizing documented health effects across organ systems.
Microplastics and Human Health: A Comprehensive Review on Exposure Pathways, Toxicity, and Emerging Risks
This comprehensive review examines microplastic exposure pathways in humans, methods of detection, and the potential toxic effects on various biological systems. The study highlights growing evidence that microplastics can enter the body through ingestion, inhalation, and dermal contact, and may affect multiple organ systems, though significant uncertainties remain about long-term health outcomes.
Metabolomics Approach in Environmental Studies: Methodologies, Application and Challenges
This review examines how metabolomics, the study of small molecules in biological systems, is being applied to environmental research to understand how chemical pollutants including microplastics affect organism metabolism. The study highlights metabolomics as a valuable tool for assessing the biological effects of environmental exposures at the molecular level, helping researchers identify biomarkers of pollutant exposure in both wildlife and humans.
Microplastics - The Human Cost
This PRISMA-guided review examined human health consequences of microplastic exposure, synthesizing 2018–2024 literature to identify inflammatory, endocrine-disrupting, and potential carcinogenic effects, and calling for expanded clinical and epidemiological research to quantify health risks in humans.
Health Effects of Exposure to Environmental Pollutants
This review examines health effects of environmental pollutants, covering both traditional contaminants like particulate matter and heavy metals and emerging pollutants like nanoparticles and microplastics, synthesizing evidence that these diverse pollutants cause overlapping adverse health outcomes.
Toxicological Consequences of Microplastic Exposure on Human Health: Mechanisms, Pathways, and Systemic Outcomes
Researchers synthesized toxicological and epidemiological evidence showing that chronic exposure to microplastics and plastic chemical additives — including BPA and phthalates — is linked to hormone disruption, cancer, metabolic disorders, and developmental problems. The authors argue that current regulations are far too weak and call for a shift toward proactive prevention, including biodegradable materials and global monitoring systems.
Impact of Microplastic Exposure on Human Health: A Systematic Review of Mechanisms, Biomarkers, and Clinical Outcomes
This systematic review found that microplastics have been detected in human blood, placental tissue, and gastrointestinal samples, with proposed health mechanisms including oxidative stress, chronic inflammation, endocrine disruption, and gut microbiome alterations. While direct clinical evidence remains limited, the accumulating laboratory and observational data point to microplastics as a plausible contributor to multiple disease pathways.
Prevalence and Impact of Emerging Chemical Contaminants in the Life Style Products on Human Health
This review examines emerging chemical contaminants found in everyday consumer products, including plasticizers, flame retardants, and microplastics, assessing their prevalence and potential health risks from chronic low-level exposure.
Environmental chemistry, toxicity and health risk assessment of groundwater: Environmental persistence and management strategies
This review examines groundwater contamination from heavy metals, pesticides, microplastics, and emerging pollutants, assessing health risks and highlighting the need for integrated management strategies to protect this critical freshwater resource.