Papers

61,005 results
|
Article Tier 2

Antimicrobial Resistance Development Pathways in Surface Waters and Public Health Implications

Researchers evaluated the pathways through which antibiotic-resistant bacteria develop and spread in surface waters, identifying healthcare facilities, wastewater, agricultural runoff, and wildlife as major vehicles. The study found that antibiotic residues, heavy metals, and even climate change drive the emergence of resistance in aquatic environments. The findings highlight that surface water contamination poses a growing public health threat, particularly for food and animal handlers who face higher exposure risk.

2022 Antibiotics 86 citations
Article Tier 2

Aeromonas spp. in Freshwater Bodies: Antimicrobial Resistance and Biofilm Assembly

Researchers isolated Aeromonas bacteria from freshwater sources and examined their ability to resist antibiotics and form protective biofilms. They found that many strains carried multiple antibiotic resistance genes and could form biofilms that made them harder to eliminate. The study highlights the role of freshwater environments as reservoirs for antibiotic-resistant bacteria that can potentially affect both animal and human health.

2024 Antibiotics 6 citations
Article Tier 2

Correlation appraisal of antibiotic resistance with fecal, metal and microplastic contamination in a tropical Indian river, lakes and sewage

Researchers sampled water from Indian urban rivers, lakes, and sewage plants and found that antibiotic-resistant bacteria correlated with fecal contamination and microplastic presence, especially for certain antibiotics, while fluoroquinolone resistance appeared more linked to seasonal temperature. The study suggests microplastics may help spread antibiotic resistance in urban waterways, adding a new dimension to concerns about plastic pollution.

2020 npj Clean Water 125 citations
Article Tier 2

Emerging Issues on Antibiotic-Resistant Bacteria Colonizing Plastic Waste in Aquatic Ecosystems

Researchers found antibiotic-resistant bacteria colonizing plastic waste submerged in an inland water body, including species related to human pathogens like Klebsiella. All isolated bacteria showed high resistance to multiple antibiotics, and they carried numerous antibiotic resistance genes. This is concerning because plastic waste in waterways can serve as a platform for drug-resistant bacteria to multiply and potentially spread to humans through contaminated water.

2024 Antibiotics 10 citations
Article Tier 2

Antidrug resistance in the Indian ambient waters of Ahmedabad during the COVID-19 pandemic

Researchers compared antibiotic resistance patterns in Escherichia coli isolated from ambient water in Ahmedabad, India before and during the COVID-19 pandemic, finding increased multi-drug resistance during the pandemic period, likely linked to elevated antibiotic consumption.

2021 Journal of Hazardous Materials 45 citations
Article Tier 2

Antibiotic resistome in groundwater and its association with mountain springs and river

Researchers characterized antibiotic resistance genes in peri-urban groundwater alongside mountain spring and river sources, finding 261 distinct resistance genes in groundwater and identifying natural water sources as contributors to groundwater antibiotic resistome profiles.

2023 Ecotoxicology and Environmental Safety 11 citations
Article Tier 2

Microplastics in fresh- and wastewater are potential contributors to antibiotic resistance - A minireview

Researchers reviewed the link between microplastic pollution and the spread of antibiotic resistance in freshwater environments, finding that microplastic surfaces host unique bacterial communities enriched in antibiotic-resistant bacteria and the resistance genes they can share with other microbes. The close packing of bacteria in these plastic-surface biofilms may accelerate the spread of drug-resistant pathogens through drinking water sources, though the full health implications remain poorly understood.

2022 Journal of Hazardous Materials Advances 31 citations
Article Tier 2

Knowledge gaps in the assessment of antimicrobial resistance in surface waters

This review identifies knowledge gaps in assessing antimicrobial resistance in surface waters, highlighting uncertainties about the selection pressure from antibiotics and heavy metals and the impact on aquatic organisms and human health.

2021 FEMS Microbiology Ecology 46 citations
Article Tier 2

Profiling of Antibiotic Residues in Surface Water of River Yamuna Stretch Passing through Delhi, India

Researchers detected antibiotic residues in the River Yamuna passing through Delhi, with ofloxacin found at the highest concentration (145 ng/mL), and observed significant seasonal and spatial variation linked to hospital discharge, drug manufacturing, and agricultural runoff.

2023 Water 40 citations
Article Tier 2

Abundance and Antimicrobial Resistance of Three Bacterial Species along a Complete Wastewater Pathway

A year-long study of a Swedish wastewater pathway found that antibiotic-resistant bacteria were most abundant in hospital wastewater and that resistance profiles mirrored local antibiotic consumption. Wastewater treatment plants also process microplastics, and understanding how bacteria move through these systems is relevant to the plastisphere's role in spreading resistance.

2019 Microorganisms 44 citations
Article Tier 2

Antibiotic resistance genes in treated wastewater and in the receiving water bodies: A pan-European survey of urban settings

Researchers surveyed 16 wastewater treatment plants across ten European countries and found that antibiotic resistance genes — DNA instructions that help bacteria survive antibiotics — are consistently released into rivers receiving treated wastewater. The study found that plants with more biological treatment steps had lower levels of these genes, suggesting that upgrading treatment infrastructure could reduce the spread of antibiotic resistance in the environment.

2019 Water Research 341 citations
Article Tier 2

Antibiotic and Non-Antibiotic Determinants of Antimicrobial Resistance: Insights from Water Ecosystems

This review explains how non-antibiotic pollutants like heavy metals, biocides, and microplastics are contributing to antibiotic resistance in water systems, beyond the well-known problem of antibiotic overuse. Wastewater treatment plants are hotspots where these pollutants interact with bacteria, promoting the spread of resistance genes through mobile genetic elements. The findings are concerning for human health because drug-resistant bacteria from water environments can ultimately reach people through drinking water and food.

2024 ACS ES&T Water 10 citations
Article Tier 2

On the Generation, Impact and Removal of Antibiotic Resistance in the Water Environment

This review explains how antibiotic resistance develops and spreads through water environments — including rivers, groundwater, and wastewater. The findings are relevant to microplastics because plastic particles in water are known to accumulate antibiotic-resistant bacteria, potentially accelerating the spread of drug resistance through aquatic systems.

2023 BIO Web of Conferences 1 citations
Article Tier 2

The nexus of microplastics, food and antimicrobial resistance in the context of aquatic environment: Interdisciplinary linkages of pathways

This review examines how microplastics in aquatic environments serve as surfaces where bacteria can grow, share antibiotic resistance genes, and then enter the food chain through contaminated seafood. The combination of microplastic pollution and antimicrobial resistance creates a compounding threat, as resistant bacteria riding on plastic particles can survive water treatment and reach humans. The authors call for interdisciplinary research connecting environmental science and public health to address this growing risk.

2025 Journal of Contaminant Hydrology 7 citations
Article Tier 2

Comparison of the Antibiotic Resistance of Escherichia coli Populations from Water and Biofilm in River Environments

Researchers compared antibiotic resistance in E. coli populations from river water versus sediment and biofilm samples at locations upstream and downstream of urban areas in Austria. They found that biofilm and sediment environments harbored bacteria with higher rates of antibiotic resistance compared to the water column. The study suggests that river biofilms may serve as reservoirs for antibiotic-resistant bacteria, with implications for how pollutants including microplastics interact with microbial communities.

2024 Pathogens 12 citations
Article Tier 2

Impact of wastewater treatment plant effluent discharge on the antibiotic resistome in downstream aquatic environments: a mini review

This review summarizes how wastewater treatment plants release antibiotic-resistant bacteria and resistance genes into rivers and lakes through their treated water. Current treatment processes cannot fully remove these resistance factors, allowing them to spread in downstream water bodies and potentially reach humans through drinking water and the food chain. The review is relevant to microplastics research because microplastics in wastewater can serve as surfaces where resistant bacteria grow and spread.

2023 Frontiers of Environmental Science & Engineering 31 citations
Article Tier 2

Antibiotic resistance genes and virulence factors in the plastisphere in wastewater treatment plant effluent: Health risk quantification and driving mechanism interpretation

Researchers found that microplastics in treated wastewater carry significantly more disease-causing bacteria, antibiotic resistance genes, and virulence factors on their surfaces compared to the surrounding water. This means microplastics released from wastewater treatment plants into rivers and lakes could spread antibiotic-resistant infections, posing a direct risk to communities that rely on these water sources.

2024 Water Research 54 citations
Article Tier 2

The problem of contamination of aquatic ecosystems with antibiotics (a review)

This review examines the contamination of aquatic ecosystems by antibiotics, synthesizing global data on risks associated with antibiotic presence in ocean and freshwater environments, including effects on aquatic organisms and the promotion of antibiotic resistance. The authors assess quantitative and qualitative contamination using bivalves as bioindicators and evaluate the spread of resistance genes through aquatic biocenoses.

2023 Ribogospodarsʹka nauka Ukraïni 3 citations
Article Tier 2

Occurrence of Antibiotic Resistance in Lotic Ecosystems

This review examines the occurrence and spread of antibiotic resistance genes and antibiotic-resistant bacteria in lotic (flowing water) ecosystems, analyzing how rivers and streams serve as reservoirs and conduits for the environmental dissemination of antibiotic resistance. Researchers synthesized evidence showing that agricultural runoff, wastewater discharge, and hospital effluents are major contributors to resistance gene loads in freshwater systems.

2022 THE SCIENTIFIC TEMPER 1 citations
Article Tier 2

Comparison of Antibiotic Resistance of Escherichia coli Populations from Water or Sediment in Rivers Environments

This study compared antibiotic-resistant E. coli in river water and sediment, examining how bacteria form biofilms and stabilize resistance in these environments. Microplastics in aquatic environments are known to promote biofilm formation and concentrate antibiotic resistance genes, amplifying this public health concern.

2023 Preprints.org 1 citations
Article Tier 2

Water and sanitation: an essential battlefront in the war on antimicrobial resistance

This review examines the role of water and sanitation infrastructure in combating antimicrobial resistance, identifying wastewater and contaminated water as key transmission routes for resistant bacteria and resistance genes. While focused on AMR broadly, the study notes that microplastics in water systems can serve as substrates for biofilm formation and may facilitate the spread of antimicrobial resistance in aquatic environments.

2018 FEMS Microbiology Ecology 181 citations
Review Tier 2

Proclivities for prevalence and treatment of antibiotics in the ambient water: a review

This review critically examines the prevalence of antibiotics in ambient water systems and the challenges of treating antibiotic-contaminated water. Researchers found that antibiotic resistance in water environments has emerged as a major public health concern, driven by pharmaceutical runoff and inadequate wastewater treatment. The study evaluates various treatment technologies and emphasizes the need for better monitoring and removal strategies to address this growing threat to water quality.

2020 npj Clean Water 161 citations
Article Tier 2

The Sources and Potential Hosts Identification of Antibiotic Resistance Genes in the Yellow River, Revealed by Metagenomic Analysis

Researchers used metagenomic analysis to characterize antibiotic resistance genes in the Yellow River, identifying their sources and potential bacterial hosts, finding that resistance genes against colistin and carbapenems were present and tracing their origins to agricultural, municipal, and industrial inputs along the river.

2022 International Journal of Environmental Research and Public Health 6 citations
Article Tier 2

Enrichment of Antibiotic Resistance Genes on Plastic Waste in Aquatic Ecosystems, Aquatic Animals, and Fishery Products

This review examines how plastic waste in water creates surfaces where antibiotic-resistant bacteria thrive and share resistance genes with each other. Microplastics in rivers, oceans, and fish farms were consistently found to harbor more antibiotic resistance genes than natural materials like rocks or sand. Since fish and shellfish can accumulate these microplastic-associated resistant bacteria, there is a risk that drug-resistant infections could reach humans through the seafood supply chain.

2025 Antibiotics 5 citations