Papers

61,005 results
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Article Tier 2

Bibliometric analysis of global research trends on pyroptosis in lung disease

This bibliometric analysis mapped global research trends on pyroptosis (inflammatory cell death) in lung disease from 2000 to the present, identifying key countries, institutions, and collaboration networks driving this emerging field. The analysis shows growing research attention on the link between pyroptosis and acute lung injury, with future focus likely to expand to other lung conditions.

2022 Frontiers in Immunology 9 citations
Article Tier 2

Mechanism of microplastics in respiratory disease from 2020 to 2024: visualization and bibliometric analysis

A bibliometric and visualization analysis mapped five years of research on the mechanisms by which microplastics cause respiratory disease, identifying oxidative stress, inflammatory pathways, and microplastic accumulation in lung tissue as the dominant topics in this rapidly growing field.

2025 Frontiers in Medicine
Article Tier 2

Nexus Between Sarcopenia and Microbiome Research: A Bibliometric Exploration

Researchers conducted a bibliometric analysis of the intersection between sarcopenia and microbiome research, analyzing 997 articles from the Science Citation Index Extended Database to map scientific production, international collaboration networks, and emerging research hotspots in this growing field.

2024 Journal of Multidisciplinary Healthcare 1 citations
Article Tier 2

Targeting Regulated Cell Death Pathways in COPD: Mechanisms and Therapeutic Strategies

This review examines how multiple regulated cell death pathways — including apoptosis, necroptosis, pyroptosis, ferroptosis, and autophagy — contribute to chronic obstructive pulmonary disease progression and discusses these pathways as potential therapeutic targets.

2025 Cells
Article Tier 2

Autophagy affects hepatic fibrosis progression by regulating macrophage polarization and exosome secretion

This study found that autophagy regulates hepatic fibrosis progression by controlling macrophage polarization and exosome secretion, which in turn modulates hepatic stellate cell activation.

2023 Environmental Toxicology 16 citations
Article Tier 2

Knowledge mapping of research on the mitochondrial unfolded protein response: a bibliometric and visual analysis

This bibliometric and visual analysis maps the global research landscape on the mitochondrial unfolded protein response (UPRmt), identifying key contributing countries, institutions, and authors, and calling for stronger international collaboration in this growing field.

2023 Annals of Translational Medicine 8 citations
Article Tier 2

Machine-Learning-Based Bibliometric Analysis of Pancreatic Cancer Research Over the Past 25 Years

Machine learning and semantic analysis were applied to 25 years of pancreatic cancer research publications indexed under medical subject headings, mapping past and current research themes and predicting future directions. The study demonstrates that computational bibliometric methods can reveal evolving research priorities in cancer science more efficiently than traditional literature reviews.

2022 Frontiers in Oncology 19 citations
Article Tier 2

Drosophila as a Robust Model System for Assessing Autophagy: A Review

This review explores how the fruit fly Drosophila melanogaster serves as a powerful research model for studying autophagy, the cellular recycling process that plays roles in aging, immune response, and disease. Researchers describe the genetic tools and techniques available in Drosophila that allow detailed investigation of autophagy mechanisms in a living organism. The study highlights that insights from fruit fly research continue to advance our understanding of how autophagy functions in more complex organisms, including humans.

2023 Toxics 17 citations
Article Tier 2

The application of machine learning to air pollution research: A bibliometric analysis

Researchers conducted a bibliometric analysis of 2,962 studies on machine learning applied to air pollution research from 1990 to 2021, finding that publications surged after 2017, with most research focused on pollutant characterization, short-term forecasting, detection improvement, and emission control. The analysis reveals that machine learning is becoming a powerful tool for understanding atmospheric chemistry and managing air quality, though global collaboration remains limited.

2023 Ecotoxicology and Environmental Safety 48 citations
Article Tier 2

Identifying emerging trends in rheumatoid arthritis research: A scientometric analysis

This scientometric analysis maps research trends in rheumatoid arthritis over two decades, identifying key topics and collaborative networks in the field. It is a bibliometric study of autoimmune disease research with no direct connection to microplastics.

2020 Research Square (Research Square)
Article Tier 2

Biological Modulation of Autophagy by Nanoplastics: A Current Overview

This review examines how nanoplastics interfere with autophagy, the cell's natural recycling and cleanup process. While cells initially activate autophagy to deal with nanoplastic particles, prolonged exposure can overwhelm this system, leading to cell damage and death. Understanding this process is important because it may explain how long-term nanoplastic exposure contributes to tissue damage and disease in humans.

2025 International Journal of Molecular Sciences 6 citations
Article Tier 2

Effect of microplastics deposition on human lung airways: A review with computational benefits and challenges

This review examines how microplastics deposited in human lungs can cause inflammation, oxidative stress, and reduced lung function. Because these tiny particles can reach deep into the lungs where oxygen enters the blood, they raise concerns about long-term respiratory disease and the possibility of spreading to other organs.

2024 Heliyon 126 citations
Article Tier 2

Micro- and Nanoplastic-Induced Respiratory Disease and Dysfunction: A Scoping Review

A systematic scoping review of 68 studies found that inhaled micro- and nanoplastics are detected in human lung tissue and associated with pulmonary inflammation, fibrosis, and impaired lung function, though most evidence comes from occupational settings and in vitro experiments.

2025 Microplastics
Systematic Review Tier 1

The Effect of Nanoplastics and Microplastics on Lung Morphology and Physiology: a Systematic Review

This systematic review examines how inhaled microplastics and nanoplastics affect lung structure and function. The research found that indoor microplastic concentrations are often higher than outdoor levels due to household materials shedding fibers, and that inhaled particles can accumulate in different parts of the lungs. These findings suggest that breathing in plastic particles at home and work could contribute to respiratory health problems over time.

2024 The Medical and Ecological Problems 1 citations
Article Tier 2

Visual mapping of global nanoplastics research progresses and hotspots: a scientometric assessment analysis

A scientometric analysis mapped global nanoplastics research from 2000 to the present, identifying China, the US, and European countries as leading contributors, and tracking the evolution of research hotspots from source characterization toward toxicological effects.

2023 Environmental Science and Pollution Research 4 citations
Article Tier 2

Occupational and Environmental Exposures: Trends in Publications, Diseases, and Experimental Models

A bibliometric analysis of occupational and environmental exposure research found that silica dust and microplastics are receiving increasing research focus, that pulmonary fibrosis is the most studied disease outcome, and that organ-on-chip technology remains underutilized despite its potential to bridge translational gaps.

2025 Thoracic research and practice
Article Tier 2

Bibliometric analysis of microplastics research: Advances and future directions (2020–2024)

This bibliometric study analyzed trends in microplastics research from 2020 to 2024, finding a rapid increase in publications with growing specialization in areas like ecotoxicology, detection methods, and pollution control. Key research hotspots include microplastic effects on human health, interactions with other pollutants, and removal technologies. The analysis reveals that while the field is maturing rapidly, significant gaps remain in understanding real-world health impacts and developing effective remediation strategies.

2024 Continental Shelf Research 10 citations
Article Tier 2

Polystyrene nanoplastics and lung cancer: Insights from network toxicology and mechanistic in vitro studies

Network toxicology analysis identified 189 potential molecular targets linking polystyrene nanoplastic exposure to lung cancer pathways, and in vitro experiments confirmed that nanoplastics promote lung cancer cell proliferation and resistance to apoptosis via PI3K/AKT signaling.

2025 Toxicology and Applied Pharmacology
Article Tier 2

Bibliometric Analysis of Bronchopulmonary Dysplasia in Extremely Premature Infants in the Web of Science Database Using CiteSpace Software

Researchers conducted a bibliometric analysis of bronchopulmonary dysplasia research in extremely premature infants using CiteSpace software, identifying 610 relevant articles from 2008-2020 and mapping key research clusters around oxidative stress, inflammation, and surfactant therapy.

2021 Frontiers in Pediatrics 36 citations
Article Tier 2

Unveiling the nexus: A bibliometric analysis of nano plastic’s health impact

This bibliometric analysis mapped the global research landscape on nanoplastics and human health from 2015 to 2024. Researchers found a steady annual increase in publications, with China leading in both output and international collaboration. The study identifies growing scientific interest in understanding how nanoplastics, the smallest fragments of plastic pollution, may affect human health.

2025 Journal of Education and Health Promotion 2 citations
Article Tier 2

Global trends and hotspots of gastrointestinal microbiome and toxicity based on bibliometrics

This bibliometric analysis mapped global research trends and hotspots in gastrointestinal microbiome and toxicity studies, finding that modifications to the gut microbiome could offer new directions for treating and mitigating toxic exposures.

2023 Frontiers in Microbiology 8 citations
Article Tier 2

Research Progress and Hotspots on Disposalof Landfill Leachate: A Bibliometric AnalysisUsing Knowledge Mapping Method

Not relevant to microplastics — this is a bibliometric analysis of landfill leachate treatment research from 1996–2022, tracking publication trends and identifying dominant themes such as membrane bioreactors and advanced oxidation.

2024 Polish Journal of Environmental Studies 2 citations
Article Tier 2

How do humans recognize and face challenges of microplastic pollution in marine environments? A bibliometric analysis

Researchers performed a bibliometric analysis of 1,898 publications on marine microplastics, mapping research growth, collaboration networks, and thematic trends over time, and predicting that future research will increasingly focus on biological effects, human health impacts, and policy-relevant risk characterization.

2021 Environmental Pollution 39 citations
Article Tier 2

Global trends and hotspots in research on organoids between 2011 and 2020: a bibliometric analysis

A bibliometric analysis of organoid research from 2011 to 2020 identified drug screening, disease modeling, and personalized medicine as the dominant themes, while highlighting reproducibility and functional maturity as ongoing limitations. The authors predicted that bioengineering strategies to overcome these limitations would become the next major focus of the field.

2022 Annals of Palliative Medicine 9 citations