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Mechanism of microplastics in respiratory disease from 2020 to 2024: visualization and bibliometric analysis

Frontiers in Medicine 2025
Z. Z. Du, Xia Yu, Xue Li, Ling Zhang, Yonghong Lin, Yi He, Ying Wu, Ying Wu

Summary

A bibliometric and visualization analysis mapped five years of research on the mechanisms by which microplastics cause respiratory disease, identifying oxidative stress, inflammatory pathways, and microplastic accumulation in lung tissue as the dominant topics in this rapidly growing field.

Research on the processes of MPs in the respiratory disease has advanced rapidly during the past 5 years. Human exposure (toxicity, ingestion, accumulation and metabolism), gene, oxidative stress, inflammation and cell death are the five main research area. In the following stage, deep studies on the connection of various mechanisms will be conducted, and efforts are expected to minimize the level of MPs in the human body, thus reducing the risk to humans.

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