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Global trends and hotspots in research on organoids between 2011 and 2020: a bibliometric analysis
Summary
A bibliometric analysis of organoid research from 2011 to 2020 identified drug screening, disease modeling, and personalized medicine as the dominant themes, while highlighting reproducibility and functional maturity as ongoing limitations. The authors predicted that bioengineering strategies to overcome these limitations would become the next major focus of the field.
Our study used bibliometric analysis to provide an in-depth understanding of the trends and hotspots of organoid research. The primarily important subject matters are drug screening, disease modeling, personalized medicine, regenerative medicine, and developmental biology. However, this field still faces limitations in the form of lack of reproducibility, low levels of maturity and function, and the absence of appropriate readouts. Therefore, these five significant topics, and possible solutions to limitations (involving bioengineering strategies), might be noteworthy in the future.
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