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61,005 resultsShowing papers similar to Toxicological Evaluation of Effects of Some Environmental Pollutants on Intestinal Microbiota: Traditional Review
ClearMicroplastics and their interactions with microbiota
This review examines how microplastics interact with microbiota (the communities of microorganisms in the environment and in living bodies). Microplastics can carry harmful bacteria and disrupt the natural balance of microbial communities in soil, water, and the human gut. The disruption of gut microbiota by microplastics is particularly concerning because a healthy gut microbiome is essential for immune function, digestion, and overall health.
Research Advances on the Impact of Environmental Pollutants on Gut Microbiota
This review synthesizes evidence from animal models, human studies, and mechanistic experiments showing how microplastics, pesticides, and heavy metals each disrupt gut microbiota composition, reduce beneficial bacteria, and compromise intestinal barrier integrity and host health.
Interaction between microplastics and microorganism as well as gut microbiota: A consideration on environmental animal and human health
This review explores how microplastics interact with microorganisms in the environment and within the gut, examining implications for both animal and human health. Researchers found that microplastics can alter gut microbiota composition, promote the spread of antibiotic-resistant bacteria, and amplify the toxicity of other environmental pollutants. The study suggests that the interaction between microplastics and gut microorganisms is an important emerging area for understanding health risks.
Role-Playing Between Environmental Pollutants and Human Gut Microbiota: A Complex Bidirectional Interaction
This review examined the bidirectional relationship between environmental pollutants, including microplastics, and the human gut microbiota, highlighting how toxicants alter microbial communities while gut bacteria can metabolize or modify pollutant toxicity.
Interactions between environmental pollutants and gut microbiota: A review connecting the conventional heavy metals and the emerging microplastics
This review examines how environmental pollutants, including both heavy metals and microplastics, interact with gut bacteria in humans and animals. The authors found that these pollutants can disrupt the balance of gut microbiota, which may contribute to various health problems, and that gut bacteria can also transform pollutants in ways that change their toxicity.
Impact of microplastics on the intestinal microbiota: A systematic review of preclinical evidence
Across 28 preclinical studies, microplastics triggered intestinal dysbiosis characterized by increased Firmicutes and Proteobacteria and decreased Bacteroidetes, while increasing gut permeability and elevating pro-inflammatory cytokines including IL-1β, TNF-α, and IL-6.
Gut microbiome remodeling induced by microplastic exposure in humans
This review synthesizes evidence on how microplastic exposure affects the human gut microbiome, drawing on cross-sectional studies of people exposed through plastic food containers and other sources. Evidence indicates that microplastic exposure is associated with shifts in gut bacteria composition, including increases in certain bacterial groups linked to inflammation. The authors explore potential connections between microplastic-induced changes in gut bacteria and the development of various health conditions.
Gut microbiota, a key to understanding the knowledge gaps on micro-nanoplastics-related biological effects and biodegradation
This review explores how micro- and nanoplastics affect the community of microorganisms living in the gut, and how those same gut microbes might be able to break down plastic particles. Swallowed microplastics can disrupt the balance of gut bacteria, potentially leading to various diseases. On the other hand, some gut bacteria can actually degrade plastics into smaller, less harmful molecules, opening a possible avenue for biological cleanup.
Pollutants, microbiota and immune system: frenemies within the gut
This review summarizes how environmental pollutants, including microplastics, disrupt the gut microbiome and immune system, potentially contributing to inflammatory bowel diseases and colorectal cancer. Pollutants reduce beneficial gut bacteria while promoting inflammation, weakening the intestinal barrier, and triggering a chain of events that can push cells toward cancerous growth.
Microplastics and the gut microbiome: Emerging health concerns and strategies
This review covers how microplastic ingestion affects the gut microbiome, describing mechanisms by which microplastics cause intestinal disorders, disrupt endocrine function, and promote pathogenic bacterial growth, while also noting inhalation and dermal absorption as secondary exposure routes.
Microbial risks associated with microplastics in the food chain and possible control measures (literature review). Part 1. Dietary intake and influence on the gut microbiota
This review summarizes evidence that microplastics commonly found in food and drinking water can disrupt the human gut microbiome when ingested. Studies show that microplastics alter the composition and function of intestinal bacteria, potentially affecting digestion, immunity, and overall health. Since a healthy gut microbiome is essential for human wellbeing, this pathway of harm deserves attention alongside other known risks of microplastic exposure.
How do microplastics affect the composition and function of gut microbiota?
Researchers reviewed how microplastics may disrupt gut microbiota composition and metabolic function, noting that while dysbiosis is a likely outcome of exposure, the full scope of these effects in humans remains understudied.
How do microplastics affect the composition and function of gut microbiota?
Researchers reviewed how microplastics may disrupt gut microbiota composition and metabolic function, noting that while dysbiosis is a likely outcome of exposure, the full extent of these effects in humans remains poorly characterized and understudied.
Microplastics as an aquatic pollutant affect gut microbiota within aquatic animals
This review examined how microplastics affect the gut microbiota of aquatic animals, analyzing the roles of plastic-associated chemicals and biofilms in disrupting microbial communities from ingestion through physiological impacts.
Gut microbiota as an emerging target for the health implications of microplastics
This review examines how microplastic exposure disrupts the gut microbiome, finding evidence that microplastics damage intestinal barrier proteins, promote inflammation and oxidative stress, and may drive systemic effects including neurotoxicity and reproductive toxicity through gut-mediated pathways.
Impact of microplastics on human gut microbiota: first evidences from in vitro gut models
Researchers investigated the impact of microplastics on human gut microbiota using in vitro gut models, providing early experimental evidence of how microplastic exposure may disrupt intestinal microbial communities. The study offers foundational data on microplastic-microbiome interactions that are difficult to study directly in humans.
Potential effects of MPs and their co-pollutants on human intestinal tract
This review examines how microplastics and their co-pollutants enter and damage the human intestinal tract, summarizing evidence for microplastic-induced gut barrier disruption, microbiota alteration, and systemic translocation to other organs.
Micro(nano)plastics and Their Potential Impact on Human Gut Health: A Narrative Review
This review summarizes research on how micro- and nanoplastics affect the gut, finding that they can damage the intestinal lining, trigger immune responses, and disrupt the balance of beneficial gut bacteria in both cell studies and animal models. Since humans are primarily exposed to microplastics through food and food packaging, understanding these gut effects is essential for assessing the true health risks of plastic pollution.
Ecotoxicological impacts of microplastics to gut microbiota: Response mechanism, challenges and environmental sustainability-A review
This review summarizes how microplastics affect gut bacteria in fish, mice, and earthworms after being swallowed. Microplastics can change the balance of gut microbes and reduce their helpful functions, leading to digestive problems, slower growth, and weakened immunity. Since humans are exposed to microplastics through food and water, these findings raise concerns that our own gut health could be similarly affected.
Microplastic: A potential threat to human and animal health by interfering with the intestinal barrier function and changing the intestinal microenvironment
This review summarizes current research on how microplastics disrupt the gut environment in both animals and humans, focusing on damage to the intestinal barrier. Studies show that microplastic exposure can cause oxidative damage, inflammation, destruction of the gut lining, thinning of the protective mucus layer, and disruption of beneficial gut bacteria. While direct human evidence is still limited, the growing body of animal research suggests that microplastics could pose a meaningful threat to intestinal health.
The role of gut microbiota in MP/NP-induced toxicity
This review summarizes how micro- and nanoplastics disrupt gut bacteria and why that matters for overall health. The tiny plastic particles change the composition and function of the gut microbiome, which can trigger inflammation, weaken the intestinal barrier, and potentially contribute to diseases beyond the gut through the immune and nervous systems.
Immunotoxicity and intestinal effects of nano- and microplastics: a review of the literature
This review examines the evidence on how nano- and microplastics affect the immune system and intestinal health. The findings suggest that exposure to these particles can disrupt the gut microbiome and impair critical intestinal barrier functions, potentially contributing to the development of chronic inflammatory and immune conditions.
Microplastics and human health: unveiling the gut microbiome disruption and chronic disease risks
This review summarizes evidence that microplastics disrupt the gut microbiome, the community of bacteria in our digestive system that plays a key role in immunity, metabolism, and overall health. By altering gut bacteria balance and triggering inflammation, microplastic exposure may contribute to chronic conditions including inflammatory bowel disease, metabolic disorders, and potentially even neurological problems through the gut-brain connection.
Exploring Bacterial Interactions with Microplastics in the Human Gut Microbiome
This review explored how microplastics interact with bacteria in the human gut microbiome, examining evidence that plastic particles can alter microbial community composition, enable colonization by pathogens, and facilitate horizontal gene transfer of antibiotic resistance genes. The gut microbiome appears to be a significant site of microplastic-microorganism interaction.