Papers

61,005 results
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Article Tier 2

Forever Chemicals PFAS Global Impact and Activities, Cascading Consequences of Colossal Systems Failure: Long-Term Health Effects, Food-Systems, Eco-Systems

This comprehensive review examines PFAS (per- and polyfluoroalkyl substances) contamination across food, water, and consumer products, highlighting their interconnection with microplastic pollution. The authors document decades of delayed regulatory action and cover-ups that have contributed to widespread human exposure. Evidence indicates long-term health effects from PFAS exposure, and the review calls for stronger risk assessment tools and policy responses to address this persistent chemical contamination.

2025 Preprints.org 1 citations
Article Tier 2

Poly- and Perfluoroalkyl Substances (PFAS): Do They Matter to Aquatic Ecosystems?

This review examines PFAS, the persistent 'forever chemicals' widely used in consumer products, and their growing threat to aquatic ecosystems. Evidence indicates that PFAS accumulate in aquatic organisms, disrupt hormones, and can alter how other pollutants behave in the environment. The research is relevant to microplastic concerns because PFAS are commonly found in plastic products and can leach from microplastics into water.

2023 Toxics 46 citations
Article Tier 2

Why Aim Toward a PFAS-free Future?

This paper is not about microplastics — it reviews the environmental persistence, toxicity, and regulatory challenges associated with per- and polyfluoroalkyl substances (PFAS), the so-called 'forever chemicals,' and argues for transitioning industry toward safer substitutes using green chemistry principles.

2023 1 citations
Article Tier 2

Fate, distribution, and transport dynamics of Per- and Polyfluoroalkyl Substances (PFASs) in the environment

This review examines how PFAS, often called "forever chemicals," move through water, soil, plants, and air, with their ultra-strong carbon-fluorine bonds making them nearly indestructible in nature. While focused on PFAS rather than microplastics specifically, the two pollutants often co-occur and share similar concerns about persistence, bioaccumulation, and potential health effects.

2024 Journal of Environmental Management 34 citations
Article Tier 2

Research Progress in Current and Emerging Issues of PFASs’ Global Impact: Long-Term Health Effects and Governance of Food Systems

This review covers per- and polyfluoroalkyl substances (PFAS), commonly called "forever chemicals," which are found in food, cosmetics, drinking water, and are linked to microplastic contamination. Decades of corporate delay and mismanagement have led to widespread human exposure with potential long-term health effects being studied across the globe. The authors examine PFAS levels in food and water from multiple countries and call for stronger regulations to protect public health.

2025 Foods 20 citations
Article Tier 2

Forever Chemicals, Per-and Polyfluoroalkyl Substances (PFAS), in Lubrication

This review examines how PFAS (per- and polyfluoroalkyl substances), known as forever chemicals, are used in lubricants and greases across automotive and industrial applications, and how they enter the environment through these products. PFAS exposure is a growing health concern because these chemicals accumulate in the body and have been linked to immune system problems, cancer, and developmental issues in humans.

2024 Lubricants 44 citations
Meta Analysis Tier 1

Critical Evaluation and Meta-Analysis of Ecotoxicological Data on Per- and Polyfluoroalkyl Substances (PFAS) in Freshwater Species

This meta-analysis assessed the toxicity of PFAS ("forever chemicals" commonly found in plastics and coatings) to freshwater species. The findings suggest that even low concentrations of certain PFAS compounds can harm aquatic life, which has implications for ecosystems and the safety of our water supply.

2024 Environmental Science & Technology 26 citations
Article Tier 2

Impact of per- and polyfluorinated alkyl substances (PFAS) on the marine environment: Raising awareness, challenges, legislation, and mitigation approaches under the One Health concept

This review examines how PFAS (per- and polyfluorinated alkyl substances), often called 'forever chemicals,' are contaminating marine environments and interacting with other pollutants including microplastics. PFAS accumulate in marine food chains and can combine with microplastics to amplify toxic effects on ocean wildlife and ultimately human health through seafood consumption. The authors call for stronger regulations and cleanup strategies under a One Health approach that connects ocean, animal, and human well-being.

2023 Marine Pollution Bulletin 76 citations
Article Tier 2

The high persistence of PFAS is sufficient for their management as a chemical class

Researchers argue that the extreme environmental persistence of per- and polyfluoroalkyl substances (PFAS) is reason enough to regulate them as a single chemical class and phase out all non-essential uses. Because PFAS contain perfluoroalkyl groups that resist virtually all forms of environmental and biological breakdown, their continued release leads to irreversibly increasing concentrations in the environment. The study warns that once harmful effects are confirmed, reversing PFAS contamination will be extremely difficult and costly for society.

2020 Environmental Science Processes & Impacts 388 citations
Article Tier 2

Review of Recent Computational Research on the Adsorption of PFASs with a Variety of Substrates

This review summarizes recent computer modeling research on how PFAS, sometimes called "forever chemicals," stick to various materials, which could help develop better cleanup methods. While focused on PFAS rather than microplastics, both are persistent environmental pollutants that resist breakdown and accumulate in the body. Understanding how these chemicals interact with surfaces at the molecular level could lead to more effective ways to remove them from contaminated water and soil.

2024 International Journal of Molecular Sciences 21 citations
Article Tier 2

Microplastics as carriers of per- and polyfluoroalkyl substances (PFAS) in aquatic environment: interactions and ecotoxicological effects

Researchers reviewed how microplastics serve as carriers for per- and polyfluoroalkyl substances (PFAS), sometimes called forever chemicals, in aquatic environments. The study found that PFAS can attach to microplastic surfaces and accumulate in organisms through the food chain, potentially amplifying the toxic effects of both pollutants. The findings suggest that the combined presence of microplastics and PFAS poses a greater environmental and health risk than either pollutant alone.

2023 Water Emerging Contaminants & Nanoplastics 49 citations
Article Tier 2

Analysis of per- and polyfluoroalkyl substances (PFAS) extraction from contaminated firefighting materials: Effects of cleaning agent, temperature, and chain-length dependencies

Researchers tested how effectively 22 types of PFAS "forever chemicals" — used in firefighting foam and gear — can be removed from contaminated materials using different washing methods and temperatures. They found that shorter-chain PFAS compounds wash out more easily, and that higher temperatures improve removal, but PFAS levels can slowly rebound in materials days after cleaning.

2024 Emerging contaminants 13 citations
Review Tier 2

Environmental behavior of per- and polyfluoroalkyl substances (PFASs) and the potential role of biochar for its remediation: a review

This review summarizes how biochar, a carbon-rich material made from organic waste, can be used to clean up PFAS (per- and polyfluoroalkyl substances), the persistent "forever chemicals" found widely in the environment. Since microplastics can carry and transport PFAS through water systems, understanding how to remove PFAS is an important piece of the broader pollution picture.

2025 Biochar 22 citations
Article Tier 2

Revisiting the “forever chemicals”, PFOA and PFOS exposure in drinking water

Researchers reviewed 180 years of evidence on PFOA and PFOS — two of the most detected 'forever chemicals' (PFAS) in drinking water — finding that contamination rates increased sharply between 2018 and 2019, and that many developing countries still lack the regulations or technology to address the problem. The review calls for stronger global monitoring systems and improved filtration technologies to protect drinking water supplies.

2023 npj Clean Water 312 citations
Article Tier 2

Poly- and per-fluoroalkyl substances in water: Occurrence, analytical methodologies, and remediations strategies: A comprehensive review

This review comprehensively compiled information on per- and polyfluoroalkyl substances (PFAS) in water, covering their sources, health effects, analytical detection methods, and remediation strategies for removing these persistent contaminants from aquatic environments.

2023 Reviews in Analytical Chemistry 6 citations
Article Tier 2

PFAS: Ecological Implications, Remedial Actions and Ethical Considerations

This review covers the ecological implications of PFAS (per- and polyfluoroalkyl substances), their extreme environmental persistence due to the strength of the C-F bond, and current remediation strategies including thermal and chemical approaches. The authors also address ethical dimensions of PFAS production and regulation given their known toxicity.

2023 Journal of Agricultural Chemistry and Environment 4 citations
Article Tier 2

Food packaging solutions in the post‐per‐ and polyfluoroalkyl substances (PFAS) and microplastics era: A review of functions, materials, and bio‐based alternatives

This review examines how food packaging made with PFAS ("forever chemicals") and conventional plastics can release harmful microplastics and chemicals into the food we eat. The study highlights promising bio-based alternatives made from plant-derived materials that could replace these hazardous packaging materials and reduce our daily exposure to microplastics through food.

2024 Comprehensive Reviews in Food Science and Food Safety 29 citations
Article Tier 2

PFAS Associated with Microplastics (MPs)

This review examined the environmental and health risks of the 'forever alliance' between PFAS and microplastics, where PFAS adsorb onto MP surfaces, increasing their environmental mobility, bioavailability, and combined toxicity. The interaction amplifies the hazards of both contaminant classes and complicates risk assessment.

2025
Article Tier 2

Perfluoroalkyl and polyfluoroalkyl substances in sewage sludge: challenges of biological and thermal treatment processes and potential threats to the environment from land disposal

This review summarizes data on PFAS (per- and polyfluoroalkyl substances, also known as 'forever chemicals') found in sewage sludge, which is commonly spread on farmland. Current biological and thermal treatment methods struggle to fully remove these persistent chemicals from sludge. While focused on PFAS rather than microplastics, the findings are relevant because both contaminants accumulate in sludge and enter the food chain when that sludge is applied to agricultural soil.

2024 Environmental Sciences Europe 17 citations
Article Tier 2

Per- and Polyfluoroalkyl Substances (PFAS) as Emerging Obesogens: Mechanisms, Epidemiological Evidence, and Regulatory Challenges

This review examines growing evidence that PFAS, the 'forever chemicals' found in many consumer products, may act as obesogens, meaning they could promote obesity by disrupting hormones and fat metabolism. PFAS exposure has been linked to changes in how the body stores fat and processes lipids, with some studies suggesting maternal exposure may increase obesity risk in children. While focused on PFAS rather than microplastics, the findings are relevant because both are persistent environmental pollutants that can act as endocrine disruptors.

2024 Physiologia 10 citations
Article Tier 2

Effects of perfluoroalkyl and polyfluoroalkyl substances on soil structure and function

This review examines how PFAS (per- and polyfluoroalkyl substances) — often called forever chemicals — affect soil structure and the microbial communities that drive nutrient cycling. PFAS are found in many plastic-associated products and coatings and persist in soils for decades. The authors identify significant gaps in understanding how PFAS concentrations found in real-world soils affect ecosystem health.

2021 1 citations
Article Tier 2

The unheeded inherent connections and overlap between microplastics and poly- and perfluoroalkyl substances: A comprehensive review

This review reveals the overlooked connection between microplastics and PFAS (forever chemicals), showing that these two widespread pollutants often come from the same products and interact in the environment. Microplastics can absorb PFAS onto their surfaces and transport them through water systems, potentially increasing exposure for aquatic organisms and humans. Understanding this overlap is important because the combined effects may be more harmful than either pollutant alone.

2023 The Science of The Total Environment 45 citations
Article Tier 2

Per- and Polyfluoroalkyl Substances Concentrations are Associated with an Unfavorable Cardio-Metabolic Risk Profile: Findings from Two Population-Based Cohort Studies

Researchers found that even low blood levels of PFAS ("forever chemicals") in the general population were associated with worse cholesterol and lipoprotein profiles — a known risk factor for heart disease — with stronger harmful effects in younger adults, supporting calls for stricter regulation of these persistent chemicals.

2024 Exposure and Health 12 citations
Article Tier 2

Firefighters’ exposure to per-and polyfluoroalkyl substances (PFAS) as an occupational hazard: A review

This review examines how firefighters face elevated cancer risk from occupational exposure to PFAS, a class of toxic "forever chemicals" found in their protective gear, firefighting foam, and fire station dust. While focused on PFAS rather than microplastics directly, the research is relevant because both PFAS and microplastics are persistent environmental pollutants that accumulate in the body. PFAS are also commonly found attached to microplastic surfaces, making microplastics a potential carrier of these carcinogenic chemicals.

2023 Frontiers in Materials 68 citations