Papers

61,005 results
|
Article Tier 2

Detection of Microplastics in Human Bronchoalveolar Lavage Fluid: Preliminary Evidence of Respiratory Exposure to Environmental Contaminants

Researchers analyzed bronchoalveolar lavage fluid from eight adult patients undergoing diagnostic bronchoscopy and detected microplastics in the samples using microscopy, providing preliminary direct evidence that airborne microplastics deposit in the human respiratory tract.

2025 Cureus
Article Tier 2

Bronchoalveolar Lavage as a Diagnostic Window into Human Exposure to Microplastics and Associated Lung Changes

Bronchoalveolar lavage analysis revealed microplastics in the lower respiratory tract of human patients and showed associated inflammatory changes, providing direct evidence of pulmonary microplastic exposure and supporting the need for occupational and environmental health monitoring.

2025 Journal of Pharmacy And Bioallied Sciences
Article Tier 2

Presence of microplastics in human’s respiratory system: bronchoalveolar and bronchial lavage fluid

Researchers analyzed bronchial and bronchoalveolar lavage fluid from patients undergoing bronchoscopy and confirmed the presence of microplastics in the human respiratory system. They characterized the types, sizes, and quantities of microplastic particles found at different levels of the airways. The study provides direct evidence that microplastics deposit within human lungs and suggests that respiratory exposure is a meaningful route of human microplastic intake.

2025 Journal of Environmental Health Science and Engineering 1 citations
Article Tier 2

Microplastics in Human Bronchoalveolar Lavage Fluid

Researchers developed a new method for detecting microplastics in fluid washed from human lungs (bronchoalveolar lavage fluid) and found plastic particles present in every patient tested. They also applied Nile Red staining for the first time to visualize plastics in lung samples, which proved effective for screening and counting particles. The findings provide direct evidence that microplastics are present in the human respiratory system, with a potential link to lung inflammation.

2025 Respirology 2 citations
Article Tier 2

Microplastics in Human Bronchoalveolar Lavage Fluid

Researchers developed a method to detect microplastics in bronchoalveolar lavage fluid, a less invasive sampling technique than surgical lung biopsy, to assess human respiratory exposure. Using fluorescence microscopy and Raman spectroscopy, they identified and characterized microplastic particles in lung wash samples from patients undergoing bronchoscopy. The study suggests that lavage fluid analysis could become a practical tool for monitoring microplastic exposure in human lungs.

2025 American Journal of Respiratory and Critical Care Medicine 1 citations
Article Tier 2

Breathing plastics: Influence of airborne microplastics on the respiratory microbiome and health of human lungs (Review)

Researchers reviewed evidence showing that inhaled airborne microplastics can physically interact with the microbial community living in human lungs, disrupting its balance and triggering inflammation linked to conditions like asthma and fibrosis. Because microplastic particles have been found in lung tissue and fluid samples, inhalation is now recognized as a significant exposure route with measurable consequences for respiratory health.

2026 World Academy of Sciences Journal
Article Tier 2

Microplastics exposed by respiratory tract and exacerbation of community-acquired pneumonia: The potential influences of respiratory microbiota and inflammatory factors

Researchers found that microplastics were present in the lungs of pneumonia patients, and that patients with severe pneumonia had higher levels of microplastics in their airways than those with milder cases. The microplastics appeared to worsen lung infections by disrupting the balance of airway bacteria and increasing inflammation. This study provides early evidence that inhaled microplastics may make respiratory infections more dangerous in humans.

2025 Environment International 8 citations
Article Tier 2

Presence of airborne microplastics in human lung tissue

Researchers examined human lung tissue from autopsies and found microplastic particles and fibers in 13 out of 20 samples. The most common plastics were polyethylene and polypropylene, with particles smaller than 5.5 micrometers. This study provides direct evidence that inhaled microplastics accumulate in human lungs, raising concerns about potential long-term effects on respiratory health.

2021 Journal of Hazardous Materials 1155 citations
Article Tier 2

Respiratory Toxicity of Microplastics: Mechanisms, Clinical Outcomes, and Future Threats

This review summarized the respiratory toxicity of airborne microplastics, covering their sources, the routes by which they penetrate deep into lung tissue, and the range of clinical outcomes from chronic inflammation to potential malignancy. The authors warn that inhalation exposure represents an underappreciated and growing public health threat.

2025 Zenodo (CERN European Organization for Nuclear Research)
Article Tier 2

Airborne microplastics: Consequences to human health?

Researchers reviewed existing evidence on airborne microplastics and their potential effects on human respiratory health. Studies of workers exposed to plastic fibers and particles have documented airway inflammation and breathing difficulties, suggesting that susceptible individuals may face health risks even from environmental concentrations. The paper calls for greater awareness and future research into the health consequences of inhaling microplastic particles.

2017 Environmental Pollution 1580 citations
Clinical Trial Tier 1

New evidence of the presence of micro- and nanoplastic particles in bronchioalveolar lavage samples of clinical trial subjects

Researchers found micro- and nanoplastic particles in the lung fluid of patients undergoing bronchoscopy — a procedure that samples the deep airways — marking the first detection of airborne nanoplastics in the lower respiratory tract of living humans. All samples contained plastic particles, confirming that people in Northern Europe are regularly inhaling plastics, though the health effects remain under investigation.

2023 Heliyon 24 citations
Review Tier 2

Airborne microplastics: A narrative review of potential effects on the human respiratory system

This review consolidates research on airborne microplastics and their potential effects on the human respiratory system. Studies show that inhaled microplastics can deposit in the lungs, trigger inflammation, cause oxidative stress, and lead to cell damage and death. While human exposure evidence is still limited, animal and cell studies suggest that long-term inhalation of airborne microplastics could pose significant risks to lung health.

2023 The Science of The Total Environment 80 citations
Article Tier 2

Detection and Analysis of Microplastics in Human Sputum

Researchers analyzed sputum (mucus from the lungs) from 22 patients with respiratory diseases and found microplastics in every single sample, identifying 21 different plastic types. Polyurethane was the most common type detected, and most particles were smaller than 500 micrometers. This study provides direct evidence that humans are inhaling microplastics, with factors like smoking and medical procedures increasing the amount found in the respiratory tract.

2022 Environmental Science & Technology 494 citations
Article Tier 2

Microplastics inhalation: evidence in human lung tissue

Microplastic particles were found in human lung tissue samples collected during surgery, confirming that people inhale and retain microplastics in pulmonary tissue, with polypropylene and polyethylene terephthalate among the polymers identified, raising concerns about chronic respiratory and inflammatory effects.

2021 10 citations
Article Tier 2

Microplastics, potential threat to patients with lung diseases

This review examines the potential threat that airborne microplastics pose to people with existing lung conditions, noting that these particles have been found in human lung tissue and sputum. Researchers explored possible mechanisms by which inhaled microplastics could worsen lung diseases, including triggering inflammation and oxidative stress. The study highlights significant knowledge gaps and calls for more research into how microplastic inhalation affects respiratory health.

2022 Frontiers in Toxicology 119 citations
Systematic Review Tier 1

Deleterious effects of microplastics and nanoplastics on rodent lungs: a systematic review

This systematic review summarizes research on how inhaled micro- and nanoplastics affect the lungs in animal studies. The findings show these particles can cause lung inflammation, tissue damage, and immune responses, suggesting that breathing in airborne microplastics may pose real risks to respiratory health.

2025
Article Tier 2

First evidence of microplastics isolated in European citizens’ lower airway

Researchers provided the first evidence of microplastics in the lower airways of living European adults, using bronchoalveolar lavage fluid from 44 patients. Nearly all detected particles were microfibers averaging about 1.7 millimeters in length, with an average concentration of roughly 9 items per 100 milliliters of fluid. The findings confirm that microplastics reach deep into the human respiratory system, though the health implications require further investigation.

2022 Journal of Hazardous Materials 198 citations
Systematic Review Tier 1

A systematic review of the effects of airborne microplastic contamination on human lungs

This systematic review summarizes research showing that airborne microplastics have a negative effect on human lungs. Humans are estimated to inhale roughly 100,000 fine plastic particles every day, and the evidence suggests this exposure contributes to respiratory health problems, underscoring the need for policies to reduce plastic pollution in the air we breathe.

2024 African Journal of Reproductive Health 4 citations
Article Tier 2

Microplastics in urine, sputum and lung lavage fluid from patients with respiratory illnesses

Researchers analyzed urine, sputum (mucus from coughing), and lung fluid from 30 patients with respiratory conditions in Iran and found microplastics in all three types of samples. Sputum contained the most particles (358 total), dominated by polyurethane fibers, while urine had the fewest (9 particles). The different types and sizes of plastics found in each fluid suggest the body sorts and distributes inhaled and ingested microplastics through different pathways.

2025 Environmental Research 30 citations
Article Tier 2

Human Responsive Biomarkers of Airborne Microplastics Exposure: Evaluation and Analysis for Health and Environment

This research review looked at 14 studies to understand how tiny plastic particles in the air affect human health by measuring specific markers in our blood and lungs. The studies found that breathing in microplastics causes inflammation in our airways and lungs, similar to what happens with asthma, by triggering the body's immune response. This matters because it helps scientists develop better ways to detect early health problems from plastic pollution and create guidelines to protect people from these invisible particles we breathe every day.

2026 Aerosol and Air Quality Research
Article Tier 2

Tracing Microplastics in the Human Body: From Detection to Disease Mechanisms

This review traces the detection of microplastics across multiple human tissues — from nasal lavage and bronchoalveolar fluid to blood and lung tissue — and examines the disease mechanisms linking plastic particle accumulation to respiratory, cardiovascular, and other systemic health effects.

2025 Diagnostics
Article Tier 2

Micro- and Nanoplastic-Induced Respiratory Disease and Dysfunction: A Scoping Review

A systematic scoping review of 68 studies found that inhaled micro- and nanoplastics are detected in human lung tissue and associated with pulmonary inflammation, fibrosis, and impaired lung function, though most evidence comes from occupational settings and in vitro experiments.

2025 Microplastics
Article Tier 2

Isolation and characterization of microplastics from the human respiratory system: Sputum, broncho-alveolar lavage fluid, and pleural fluid simultaneously

In the first study of its kind in Iran, researchers found microplastics in every sample collected from the human respiratory system, including sputum, lung fluid, and the fluid surrounding the lungs. Polyester fibers were the most common type detected, and people with occupational exposure or smoking habits had higher amounts, confirming that we regularly breathe in microplastics that reach deep into our lungs.

2024 Environmental Pollution 29 citations
Article Tier 2

Microplastics in the Bronchoalveolar Lavage Fluid of Chinese Children: Associations with Age, City Development, and Disease Features

Microplastics were detected in nearly 90% of lung fluid samples from Chinese children with respiratory diseases, with an average of about 4 particles per 10 milliliters. Younger children and those living in more developed urban areas had higher levels, likely due to more indoor crawling behavior and greater surrounding plastic use. This is significant because it confirms that children are inhaling microplastics into their lungs, and younger children may be especially vulnerable.

2023 Environmental Science & Technology 76 citations