Papers

61,005 results
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Article Tier 2

Production of polyhydroxyalkanoate (PHA) biopolymer from crop residue using bacteria as an alternative to plastics: a review

This review examines how PHA, a biodegradable plastic made from crop waste using bacteria, could serve as a sustainable alternative to conventional plastics. While PHA breaks down naturally unlike traditional plastics that fragment into microplastics, challenges remain in making it heat-stable and cost-competitive enough for widespread industrial use.

2025 RSC Advances 22 citations
Article Tier 2

Characterization of newly isolated thermotolerant bacterium Cupriavidus sp. CB15 from composting and its ability to produce polyhydroxyalkanoate from glycerol

Researchers characterized a newly isolated thermotolerant bacterium, Cupriavidus sp. CB15, from composting environments and demonstrated its ability to produce polyhydroxyalkanoate (PHA) bioplastic from glycerol, offering a cost-effective route to biodegradable polymer production.

2023 Microbial Cell Factories 12 citations
Article Tier 2

A polyhydroxyalkanoate synthesised by halophilic archaeon Natrialba swarupiae

A salt-loving archaeal microorganism (Natrialba swarupiae) was found capable of producing polyhydroxyalkanoates (PHAs), a type of biodegradable bioplastic. This expands the range of microbes that can be used for sustainable plastic production, with potential to reduce reliance on petroleum-based plastics.

2023 Environmental Science Advances 2 citations
Article Tier 2

Exploiting sugar-rich feedstocks for sustainable polyhydroxyalkanoate production

Researchers investigated the use of sugar-rich agricultural feedstocks for sustainable production of polyhydroxyalkanoates (PHAs), evaluating these bacterial biopolymers as biodegradable alternatives to petrochemical plastics that contribute to microplastic pollution.

2025 Circular Agricultural Systems
Article Tier 2

Bacterial Production of Hydroxyalkanoates (PHA)

This review examines bacterial production of polyhydroxyalkanoates (PHA) as a biodegradable alternative to petroleum-based plastics, covering fermentation processes, scaling to industrial levels, and future trends, while noting that higher production costs currently prevent PHAs from competing commercially with conventional plastics.

2016 Universal Journal of Microbiology Research 32 citations
Article Tier 2

The Halophilic Bacterium Paracoccus haeundaensis for the Production of Poly(3-Hydroxybutyrate-co-3-Hydroxyvalerate) from Single Carbon Sources

This study demonstrated for the first time that Paracoccus haeundaensis can produce polyhydroxyalkanoates (PHAs) under nitrogen-limited conditions with glucose as carbon source, identifying it as a potential new bacterial host for biodegradable plastic production.

2023 Journal of Microbiology and Biotechnology 4 citations
Article Tier 2

Polyhydroxyalkanoates (PHAs) – Production, Properties, and Biodegradation

This review covers polyhydroxyalkanoates (PHAs), a class of microbially produced biopolyesters, discussing raw material innovation, microbial producer strains, bioengineering approaches for improved yields, and end-of-life biodegradation options. PHAs are presented as a genuinely circular plastic alternative due to their renewable production, biodegradability, and compatibility with existing plastic applications including food packaging.

2022 15 citations
Article Tier 2

Advancements in genetic engineering for enhanced Polyhydroxyalkanoates (PHA) production: a comprehensive review of metabolic pathway manipulation and gene deletion strategies

This review examines genetic engineering strategies for boosting production of polyhydroxyalkanoates, which are biodegradable bioplastics produced by bacteria. Researchers describe how modifying metabolic pathways and deleting competing genes can significantly increase bioplastic yields. The technology is relevant to the microplastics problem because scaling up biodegradable plastic alternatives could help reduce the accumulation of persistent conventional plastics in the environment.

2025 Bioengineered 17 citations
Article Tier 2

Production and characterization of polyhydroxyalkanoates by Halomonas alkaliantarctica utilizing dairy waste as feedstock

Researchers found that a salt-tolerant Antarctic bacterium called Halomonas alkaliantarctica can convert cheese whey — a dairy industry waste product — into polyhydroxyalkanoate (PHA), a biodegradable plastic alternative, producing up to 0.42 g/L without any additional nutrients, offering a dual benefit of waste valorization and sustainable bioplastic production.

2023 Scientific Reports 37 citations
Article Tier 2

Biosynthesis of Polyhydroxyalkanoates (PHAs) by the Valorization of Biomass and Synthetic Waste

This paper explores the production of polyhydroxyalkanoates (PHAs), biodegradable microbial polymers, from biomass and waste feedstocks as a sustainable alternative to conventional synthetic plastics. PHAs can be naturally synthesized by bacteria, offering a pathway to biodegradable plastics that do not persist as microplastic pollution.

2020 Molecules 47 citations
Article Tier 2

PHA, the Greenest Plastic So Far: Advancing Microbial Synthesis, Recovery, and Sustainable Applications for Circularity

This review examines polyhydroxyalkanoates (PHAs), a family of biodegradable plastics made by bacteria that could replace conventional petroleum-based plastics. Switching to PHAs could significantly reduce microplastic pollution because unlike traditional plastics, these materials fully break down in the environment rather than fragmenting into persistent microplastic particles.

2025 ACS Omega 15 citations
Article Tier 2

Polyhydroxyalkanoate (PHA) Biopolyesters - Emerging and Major Products of Industrial Biotechnology

This review examined polyhydroxyalkanoate biopolyesters as industrially produced biodegradable plastics, covering their microbial biosynthesis, material properties, and commercial applications as sustainable alternatives to conventional petroleum-based plastics.

2022 The EuroBiotech Journal 23 citations
Article Tier 2

A Review on Biological Synthesis of the Biodegradable Polymers Polyhydroxyalkanoates and the Development of Multiple Applications

This review covers the biological production of polyhydroxyalkanoates, a family of biodegradable bioplastics that bacteria naturally produce from waste carbon sources. Researchers found that these biopolymers have properties similar to conventional plastics like polypropylene but can fully biodegrade, making them a promising alternative to petroleum-based plastics. The study emphasizes that scaling up production and establishing proper end-of-life management are critical steps for PHAs to compete with conventional plastics and help reduce microplastic pollution.

2022 Catalysts 169 citations
Article Tier 2

Bioconversion of whey to Polyhydroxyalkanoate (PHA): Process Optimization and Yield Enhancement

Researchers investigated the microbial biosynthesis of polyhydroxyalkanoate using cheese whey as a substrate with a novel Stutzerimonas stutzeri strain, optimising the process to enhance PHA yield as a biodegradable alternative to conventional petroleum-based plastics.

2025
Article Tier 2

Beyond Intracellular Accumulation of Polyhydroxyalkanoates: Chiral Hydroxyalkanoic Acids and Polymer Secretion

This review covers polyhydroxyalkanoates (PHAs), biodegradable plastics produced by bacteria, which have potential as environmentally friendly alternatives to conventional petroleum-based plastics. Despite their versatility, PHAs remain expensive to produce at scale, limiting their commercial adoption.

2020 Frontiers in Bioengineering and Biotechnology 34 citations
Article Tier 2

Current developments on polyhydroxyalkanoates synthesis by using halophiles as a promising cell factory

Researchers reviewed how salt-loving microorganisms called halophiles can serve as efficient biological factories for producing polyhydroxyalkanoates (PHAs), a class of biodegradable plastics that could replace petroleum-based plastics. Their high salt requirements naturally prevent contamination during large-scale fermentation, and advances in metabolic engineering are making PHA production cheaper and more scalable.

2020 Microbial Cell Factories 219 citations
Article Tier 2

Comparative Genomics of Marine Bacteria from a Historically Defined Plastic Biodegradation Consortium with the Capacity to Biodegrade Polyhydroxyalkanoates

Researchers conducted comparative genomics of marine bacteria from a plastic biodegradation consortium, finding that multiple strains had the genomic capacity to biodegrade polyhydroxyalkanoate (PHA) bioplastics, with implications for understanding microbial degradation of biodegradable plastic alternatives.

2021 Microorganisms 29 citations
Article Tier 2

Identification and characterization of a novel extracellular polyhydroxyalkanoate depolymerase in the complete genome sequence of Undibacterium sp. KW1 and YM2 strains

Researchers identified a bacterial enzyme in freshwater Undibacterium species that can degrade polyhydroxyalkanoate (PHA), a type of biodegradable plastic. This discovery is relevant to developing microbially enhanced breakdown of biodegradable plastic alternatives to conventional petroleum-based plastics.

2020 PLoS ONE 20 citations
Article Tier 2

Switching from petro-plastics to microbial polyhydroxyalkanoates (PHA): the biotechnological escape route of choice out of the plastic predicament?

This review makes the case for replacing petroleum-based plastics with microbially produced biodegradable alternatives (PHAs), particularly for packaging and medical applications. If produced efficiently enough, PHAs could reduce persistent plastic waste and the resulting microplastic pollution.

2019 The EuroBiotech Journal 60 citations
Article Tier 2

Study of Bacterial Biopolymer Production by Bacillus Species

This study investigated the ability of Bacillus bacteria to produce polyhydroxyalkanoate (PHA) biopolymers, which are biodegradable alternatives to petroleum-based plastics. Microbial biopolymer production could help reduce reliance on conventional plastics that persist and accumulate in the environment.

2022 International Journal of Current Microbiology and Applied Sciences 4 citations
Article Tier 2

The synthesis of polyhydroxyalkanoates from low carbon wastewater under anaerobic-microaerobic process: effects of pH and nitrogen and phosphorus limitation

Researchers optimized conditions for producing polyhydroxyalkanoates (PHAs) — biodegradable bioplastics — from wastewater using bacteria under anaerobic-microaerobic conditions. Controlling pH and nutrient levels significantly improved PHA production yield. This work advances the development of sustainable plastic alternatives made from waste materials.

2021 Environmental Engineering Research 13 citations
Article Tier 2

What Is New in the Field of Industrial Wastes Conversion into Polyhydroxyalkanoates by Bacteria?

This review covers recent advances in using bacteria to convert industrial food waste into polyhydroxyalkanoates (PHAs), a type of biodegradable bioplastic. Using industrial waste as feedstock for bioplastic production could reduce both plastic pollution and food industry waste simultaneously.

2021 Polymers 24 citations
Article Tier 2

Microbial PolyHydroxyAlkanoate (PHA) Biopolymers—Intrinsically Natural

This review makes the case for polyhydroxyalkanoates (PHAs), naturally produced bioplastics made by bacteria, as a solution to fossil plastic pollution. Unlike conventional plastics that break down into persistent microplastics, PHAs are fully biodegradable in soil, water, and marine environments. Widespread adoption of PHAs could help reduce the growing burden of microplastic contamination that threatens ecosystems and human health.

2023 Bioengineering 62 citations
Article Tier 2

The Effectiveness of Polyhydroxyalkanoate (PHA) Extraction Methods in Gram-Negative Pseudomonas putida U

Researchers evaluated different physical and chemical methods for extracting polyhydroxyalkanoates (PHAs), a type of bioplastic, from the bacterium Pseudomonas putida. They compared traditional solvent-based approaches with more sustainable alternatives to find cost-effective extraction techniques. The study contributes to making bioplastic production more commercially viable as an alternative to petroleum-based plastics.

2025 Polymers 10 citations