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61,005 resultsShowing papers similar to Di-(2-ethylhexyl) phthalate and its Metabolites Research Trend: A Bibliometric Analysis
ClearDi-(2-ethylhexyl) phthalate and its metabolites research trend: a bibliometric analysis
This bibliometric analysis mapped research trends on di-(2-ethylhexyl) phthalate (DEHP) and its metabolites, identifying growth areas, major contributors, and gaps in understanding human exposure, metabolism, and health effects of this common plasticizer.
Assessment of endocrine-disrupting activities of alternative chemicals for bis(2-ethylhexyl)phthalate
Researchers assessed the endocrine-disrupting potential of alternative plasticizers used to replace the commonly restricted DEHP (bis(2-ethylhexyl) phthalate), finding that several substitutes also displayed hormonal activity. The results raise concerns that some replacement plasticizers used in consumer plastics may carry similar health risks as the chemicals they were designed to replace.
Occurrence and distribution of microplastic particles and the concentration of Di 2-ethyl hexyl phthalate (DEHP) in microplastics and wastewater in the wastewater treatment plant
Researchers investigated the presence and fate of microplastics during the wastewater treatment process, along with the plasticizer DEHP associated with them. They found that while treatment stages reduced microplastic numbers, the particles persisted throughout the process, and DEHP was detected in both the microplastics and surrounding wastewater. The study suggests that wastewater treatment plants are a significant pathway through which microplastics and associated chemicals enter the environment.
Leaching of di-2-ethylhexyl phthalate from biodegradable and conventional microplastics and the potential risks
Researchers compared the leaching of the plasticizer DEHP from biodegradable and conventional microplastics into seawater. They found that conventional polyethylene mulch film released the most DEHP, at about six times the amount leached from biodegradable alternatives. The study suggests that while all tested microplastics released some DEHP, the pollution risk from the leached amounts was assessed as low based on phthalate pollution indices.
Plasticiser leaching from polyvinyl chloride microplastics and the implications for environmental risk assessment
Researchers measured the leaching of diethylhexyl phthalate (DEHP) and bisphenol A (BPA) from polyvinyl chloride microplastics under simulated marine conditions, finding that both plasticizers leached in a concentration- and time-dependent manner. These findings are important for environmental risk assessments of PVC microplastics, which represent a major fraction of ocean plastic pollution.
Solving the impact of Phthalate plasticizers in relieving environment pollution
This review examines how phthalate plasticizers—particularly DEHP, DEP, and DBP found in food packaging and cosmetics—enter soil and human bodies, where they disrupt metabolic and reproductive systems and contribute to environmental plastic pollution.
Research tendency of microplastics and nanoplastics based on bibliometric analysis and perspective of the influence of human health
This review uses bibliometric analysis of over 7,000 scientific publications from 2004 to 2021 to map global research trends in microplastics and nanoplastics, identifying key topics, leading research nations, and emerging areas of concern related to human health impacts.
Trends, challenges, and research pathways in emerging contaminants: a comprehensive bibliometric analysis
This large-scale bibliometric analysis reviewed over 62,000 studies on emerging contaminants published between 2000 and 2024, finding that microplastics are among the fastest-growing areas of environmental health research. The analysis highlights that understanding how microplastics interact with other pollutants like pharmaceuticals and endocrine disruptors is a critical frontier for protecting human health.
Effect of aging on the release of di-(2-ethylhexyl) phthalate from biodegradable and petroleum-based microplastics into soil
This study found that aging processes like UV exposure and chemical oxidation cause microplastics to release more of the plasticizer DEHP, a potential carcinogen, into surrounding soil. Biodegradable PLA plastic released DEHP faster than conventional PVC or polystyrene when aged, suggesting that so-called eco-friendly plastics may not be safer in terms of chemical leaching. The findings are concerning because DEHP is known to disrupt hormones, and this study shows that weathered microplastics in soil could be a greater source of exposure than previously thought.
Perspectives on the Toxic Effects of Micro- and Nanoplastics on the Environment: A Bibliometric Analysis of the 2014 to 2023 Period
This bibliometric analysis mapped out a decade of research on the toxic effects of micro and nanoplastics, identifying key trends and knowledge gaps from 2014 to 2023. The field has grown rapidly, with studies increasingly focusing on how these tiny particles affect human health through oxidative stress, inflammation, and gut disruption. The review highlights that while environmental contamination is well documented, understanding of direct human health impacts is still developing.
Human Exposure to Micro (Nano) Plastics and Their Potential Health Impact: A Scientometric Analysis
This scientometric analysis mapped the global research landscape on human exposure to micro- and nanoplastics from 2014 to 2024, identifying nearly 3,000 published studies. The study found a progressive increase in publications over the decade, with Chinese researchers playing a particularly prominent role, and highlights growing evidence linking plastic particle exposure to inflammation, endocrine disruption, and gastrointestinal effects.
Bibliometric analysis of microplastics research: Advances and future directions (2020–2024)
This bibliometric study analyzed trends in microplastics research from 2020 to 2024, finding a rapid increase in publications with growing specialization in areas like ecotoxicology, detection methods, and pollution control. Key research hotspots include microplastic effects on human health, interactions with other pollutants, and removal technologies. The analysis reveals that while the field is maturing rapidly, significant gaps remain in understanding real-world health impacts and developing effective remediation strategies.
Bibliometric Analysis of the Toxicity of Bisphenol A
This bibliometric analysis mapped global research output on bisphenol A toxicity, identifying key research trends, influential publications, and emerging focus areas including endocrine disruption, reproductive toxicity, and neurodevelopmental effects.
Reproductive Effects of Phthalates and Microplastics on Marine Mussels Based on Adverse Outcome Pathway
Researchers found that microplastics and the chemical plasticizer DEHP that leaches from them work together to disrupt reproductive function in female mussels by interfering with estrogen signaling and reducing hormone levels. While this study focused on marine mussels, DEHP is a known endocrine disruptor in humans as well, and the findings illustrate how microplastics can release harmful chemicals that affect hormone systems.
Adsorption of di (2-ethylhexyl) phthalate (DEHP) to microplastics in seawater: a comparison between pristine and aged particles
Natural aging of polyethylene and polystyrene microplastics in seawater over three months increased their adsorption capacity for the plasticizer DEHP compared to pristine particles, due to surface oxidation and biofilm formation. The results indicate that environmentally aged MPs are stronger vectors for hydrophobic contaminants than fresh MPs used in most laboratory studies.
Global research hotspots and trends on microplastics: a bibliometric analysis
A bibliometric analysis of microplastics publications from 1990 to 2022 found a 19-fold increase in publications and 35-fold increase in citations since 2015, with research clustering around distribution, toxicity, analytical methods, and adsorption of co-pollutants.
Toxicological Consequences of Microplastic Exposure on Human Health: Mechanisms, Pathways, and Systemic Outcomes
Researchers synthesized toxicological and epidemiological evidence showing that chronic exposure to microplastics and plastic chemical additives — including BPA and phthalates — is linked to hormone disruption, cancer, metabolic disorders, and developmental problems. The authors argue that current regulations are far too weak and call for a shift toward proactive prevention, including biodegradable materials and global monitoring systems.
Global trends and prospects in microplastics research: A bibliometric analysis
Researchers conducted a bibliometric analysis of global microplastics research using the Web of Science database from 1986 to 2019. The study found that publications on microplastics increased significantly since 2011, with research hotspots and trends shifting from marine contamination surveys toward understanding ecological impacts and human health implications.
Comprehensive Insight from Phthalates Occurrence: From Health Outcomes to Emerging Analytical Approaches
This review summarizes the widespread occurrence of phthalates, chemicals commonly used as plasticizers in plastic products, and their potential health effects including endocrine disruption and reproductive harm. The study also surveys emerging analytical methods for detecting phthalates in food, water, and biological samples, highlighting the challenge of daily human exposure through consumer products.
Microplastics and human health: A scientometric analysis
Researchers conducted a scientometric analysis of the scientific literature on microplastics and human health, mapping research trends and publication patterns. The study reveals a rapidly growing body of evidence exploring how ubiquitous microplastic contamination may affect human health, while identifying gaps in current research that need further investigation.
Current Trends, Spatio‐Temporal Dynamics of Microplastics Research and Global Public Health: A Scientometric Study
This scientometric study analyzes trends in microplastic research and its connection to public health, finding a rapid increase in published studies over recent years. The analysis maps how the field has grown globally and identifies key research themes connecting microplastics to human health concerns. The increasing volume of research reflects growing scientific recognition that microplastics are a significant public health issue.
Microplastics as Emerging Contaminants: Investigating their Potential to Alter Human Metabolic and Endocrine Systems
This review investigated the potential of microplastics to alter human hormone signaling, synthesizing evidence that plastic particles and their chemical additives can act as endocrine disruptors at environmentally relevant concentrations. The paper highlighted reproductive and metabolic pathways as areas of particular concern.
Phthalate diester occurrence in marine feed and food (Mediterranean Sea)
Researchers detected phthalate diesters in Mediterranean Sea zooplankton, fish, and bivalves, with DEHP found in all zooplankton samples and 30% of fish, demonstrating how microplastics transport these endocrine-disrupting chemicals through marine food webs.
Consequences of Exposure to Phthalates, Micro Plastics and Nano-plastics on the Organisms
This review summarizes the toxic effects of microplastics, polystyrene, and phthalate plasticizers (BPA, DBP, DEHP) on vertebrates and invertebrates. These chemicals enter organisms through food, water, and air, causing hormonal disruption, reproductive harm, and other health effects across a wide range of species.