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20 resultsShowing papers similar to Copper-Induced Ionoregulatory Disturbance, Histopathology, and Transcriptome Responses in Freshwater Mussel (Anodonta woodiana) Gills
ClearTranscriptome analysis provides insights into copper toxicology in piebald naked carp (Gymnocypris eckloni)
Researchers exposed piebald naked carp to copper — a common water pollutant — and found it significantly disrupted gene activity in the gills and liver, particularly genes involved in building proteins, suggesting that fish respond to metal-induced stress by broadly slowing down protein production as a protective mechanism.
Molecular biomarker responses in the freshwater mussel Anodonta anatina exposed to an industrial wastewater effluent
Researchers exposed freshwater mussels to industrial wastewater effluent containing elevated levels of copper, nickel, and zinc, then measured a panel of molecular stress markers in gill and digestive tissue. While most markers showed little change, increased nerve enzyme activity and heat shock protein expression were detected, suggesting mussels can serve as sensitive pollution bioindicators but require more research to standardize responses.
Exploration of immune response mechanisms in cadmium and copper co-exposed juvenile golden cuttlefish (Sepia esculenta) based on transcriptome profiling
Researchers used transcriptome analysis to explore immune responses in juvenile golden cuttlefish co-exposed to cadmium and copper, identifying 15 key immune-regulating genes and evidence of inflammatory and innate immune activation.
Pre-Exposure of Common Carp to Ambient Copper and Microplastic Changes the Gill Ionoregulaion-Related Transcripts During Saltwater Exposure
Common carp were pre-exposed to copper alone or with polyvinyl chloride microplastics for 14 days, then challenged with brackish water to test how microplastic co-exposure alters gill physiology and metal accumulation. Combined exposure changed gill copper concentrations and altered physiological responses to salinity stress, suggesting microplastics modify how fish handle heavy metal toxicity.
Hypoxia in the Blue Mussel Mytilus chilensis Induces Transcriptome Shift Associated with Endoplasmic Reticulum Stress, Metabolism, and Immune Response.
Scientists used gene expression analysis to study how low-oxygen conditions affect the blue mussel Mytilus chilensis at the molecular level. Researchers found that hypoxia triggered stress responses in the mussels' gills, digestive glands, and muscles, including cellular stress pathways, metabolic shifts, and immune changes. The study highlights how climate-driven oxygen depletion in coastal waters can stress economically important shellfish species.
Impact of Pb Toxicity on the Freshwater Pearl Mussel, Lamellidens marginalis: Growth Metrics, Hemocyto-Immunology, and Histological Alterations in Gill, Kidney, and Muscle Tissue
Researchers found that lead toxicity in freshwater pearl mussels (Lamellidens marginalis) caused reduced growth, impaired hemocyte immune function, and significant histopathological damage, demonstrating heavy metal vulnerability in this ecologically important species.
Effects of Acute Ammonia Stress on Antioxidant Responses, Histopathology and Ammonia Detoxification Metabolism in Triangle Sail Mussels (Hyriopsis cumingii)
Triangle sail mussels exposed to sub-lethal ammonia concentrations showed antioxidant enzyme activation followed by inhibition, with the highest stress responses in gills and hepatopancreas and histopathological damage suggesting oxidative stress as a key mechanism of ammonia toxicity.
Transcriptional Responses as Biomarkers of General Toxicity: A Systematic Review and Meta-analysis on Metal-Exposed Bivalves
This meta-analysis found that metallothionein and heat shock protein 70 are the most reliable transcriptional biomarkers for detecting metal toxicity in bivalves, showing consistent upregulation across different metal types and concentrations. These biomarkers could improve environmental monitoring of metal contamination in aquatic ecosystems.
Copper and Microplastic Exposure Affects the Gill Gene Expression of Common Carp During Saltwater Challenge
This study examined how combined copper and microplastic exposure affects gill gene expression in common carp, finding synergistic stress responses including upregulation of genes involved in oxidative stress defense and immune function.
Physiological and transcriptome analysis of Mytilus coruscus in response to Prorocentrum lima and microplastics
The combined effects of diarrhetic shellfish toxin and microplastics on the mussel Mytilus coruscus were assessed at physiological and transcriptomic levels, revealing synergistic disruption of immune function, antioxidant responses, and metabolic pathways. The study provides molecular-level evidence of interactive toxicity between two common coastal contaminants.
Insights into the Response in Digestive Gland of Mytilus coruscus under Heat Stress Using TMT-Based Proteomics
Researchers investigated how heat stress affects the digestive gland of thick-shelled mussels using advanced protein analysis techniques. They found significant changes in proteins related to immune defense, energy metabolism, and stress response, revealing the biological mechanisms behind heat-related mussel die-offs. While focused on temperature stress, the study provides foundational knowledge about mussel resilience that is relevant to understanding how environmental stressors, including pollutants, affect these important marine organisms.
The response of the Mediterranean mussel Mytilus galloprovincialis (Lamarck, 1819) exposed to copper-doped zinc nanoparticles
This study is not about microplastics; it examines how copper-doped zinc oxide nanoparticles affect the physiology and biochemistry of Mediterranean mussels (Mytilus galloprovincialis) used as marine pollution bioindicators.
Effects of Copper Exposure on Oxidative Stress, Apoptosis, Endoplasmic Reticulum Stress, Autophagy and Immune Response in Different Tissues of Chinese Mitten Crab (Eriocheir sinensis)
Researchers investigated the effects of copper exposure on oxidative stress, apoptosis, endoplasmic reticulum stress, autophagy, and immune response across multiple tissues of Chinese mitten crab. The study found that copper exposure at various concentrations triggered dose-dependent toxic responses in hemolymph, hepatopancreas, gills, and muscle, providing insights into how heavy metal contamination affects crustacean physiology.
Interactive Immunomodulation in the Mediterranean Mussel Mytilus galloprovincialis Under Thermal Stress and Cadmium Exposure
Combined exposure to elevated temperature and cadmium in Mediterranean mussels triggered complex interactive effects on immune and antioxidant systems, with simultaneous stressors producing non-additive responses that highlight the difficulty of predicting organism health in multiply polluted warming seas.
Single and repetitive microplastics exposures induce immune system modulation and homeostasis alteration in the edible mussel Mytilus galloprovincialis
Researchers examined transcriptome-wide gene expression changes in Mediterranean mussels after single and repeated microplastic exposures, finding significant immune system modulation and disruption of cellular homeostasis. The study suggests that both short-term and chronic microplastic exposure can alter immune regulation pathways in filter-feeding bivalves, with repeated exposures showing cumulative effects.
De novo transcriptome assembly of the Perna viridis: A novel invertebrate model for ecotoxicological studies
Researchers created the first detailed gene reference map for the gill tissue of the Asian green mussel, an important species for monitoring ocean pollution. They identified over 47,000 gene sequences, including many related to immune defense and stress responses. This genetic resource will help scientists better understand how marine organisms respond to environmental contaminants like microplastics and heavy metals at the molecular level.
Seasonal assessment of selected trace elements in grass carp (Ctenopharyngodon idella) blood and their effects on the biochemistry and oxidative stress markers
Researchers monitored trace metal concentrations in the blood of grass carp across seasons and found significant seasonal differences, along with statistical links between metals like zinc, iron, and copper and markers of liver function, oxidative stress, and metabolism. The findings show that environmental metal pollution has measurable physiological effects on freshwater fish, which are continuously exposed through their aquatic habitat.
Oxidative Stress in Far Eastern Mussel Mytilus trossulus (Gould, 1850) Exposed to Combined Polystyrene Microspheres (µPSs) and CuO-Nanoparticles (CuO-NPs)
Researchers exposed the marine mussel Mytilus trossulus to polystyrene microspheres and copper oxide nanoparticles alone and in combination for 5 days, finding that both contaminants induced oxidative stress and that combined exposure enhanced lysosomal membrane damage compared to single exposures. The battery of biomarkers including lipid peroxidation, antioxidant activity, and DNA damage provided a sensitive profile of combined toxicity.
Toxicopathic effects of lithium in mussels
Researchers investigated the toxicity of lithium in mussels (Mytilus galloprovincialis) through acute and sublethal exposure tests, finding that lithium caused significant histopathological changes and oxidative stress, raising concerns about increasing lithium contamination in marine environments.
Histopathological damage and stress‐ and immune‐related genes' expression in the intestine of common carp, Cyprinus carpio exposed to copper and polyvinyl chloride microparticle
Researchers examined the combined effects of copper and PVC microplastics on common carp intestines, finding that co-exposure caused greater histopathological damage and altered stress- and immune-related gene expression compared to either contaminant alone.