Papers

20 results
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Article Tier 2

Microplastics: challenges of assessment in biological samples and their implication for in vitro and in vivo effects

This review examines the challenges of detecting and assessing microplastics in biological samples, noting that analytical limitations and lack of standardized methods hinder our understanding of health effects. The study highlights that humans are exposed to microplastics primarily through ingestion and inhalation, and that more long-term studies with standardized protocols are needed to understand the full scope of potential biological impacts.

2023 Environmental Science and Pollution Research 7 citations
Article Tier 2

Microplastic Contamination: An Introduction to an Emerging Issue

This review examines microplastics as emerging environmental pollutants, covering their persistence in the environment, accumulation in aquatic organisms, and the need for standardized detection and monitoring approaches to address growing contamination concerns.

2025
Article Tier 2

Microplastics in Humans: A Critical Review of Biomonitoring Evidence and Immune–Metabolic Associations

This review critically evaluates the current evidence on microplastic detection in human tissues and biological fluids, focusing on methodological challenges and the potential biological mechanisms of action. Researchers found significant variation across studies due to differences in analytical techniques and sample handling protocols. The study highlights emerging evidence linking microplastic presence in the body to immune and metabolic disruptions, while noting that standardized detection methods are urgently needed.

2025 Applied Sciences 1 citations
Article Tier 2

Microplastic contamination: a human health concern and an analytical challenge

This review examined how microplastics (5 mm–0.1 μm) and nanoplastics (down to 1 nm) contaminate food, water, and air, summarizing harmful effects on marine and terrestrial ecosystems and discussing analytical challenges in detecting and quantifying these particles in environmental and food matrices.

2025 UniTERAMO Research Catalog (University of Teramo)
Article Tier 2

A critical viewpoint on current issues, limitations, and future research needs on micro- and nanoplastic studies: From the detection to the toxicological assessment.

This critical review examines the current methods for detecting and characterizing micro- and nanoplastics in various environmental samples, as well as reported toxic effects from in vivo and in vitro studies. The authors found that while substantial effort has been made to understand microplastic behavior, the scientific community is still far from a complete understanding of how these particles behave in biological systems. The review calls for improved standardized protocols and more studies focused on uptake kinetics, accumulation, and biodistribution.

2019 Environmental Research 163 citations
Article Tier 2

Microplastics: challenges of assessment in biological samples and their implication for in vitro and in vivo effects

This review covers how microplastics enter the human body through ingestion and inhalation, the challenges of detecting and measuring them in biological samples, and the evidence for harmful effects ranging from inflammation to hormonal disruption. Standardising methods for measuring microplastics in tissues and bodily fluids is a key obstacle to advancing human health research. The review provides a useful framework for understanding what we know and what still needs to be established about microplastic risks to people.

2023 Research Square (Research Square)
Article Tier 2

Micro(nano)plastics, an emerging health problem

This review frames micro- and nanoplastics as an emerging human health problem, synthesizing evidence of exposure routes, organ-level accumulation, and biological effects, and calling for updated regulatory frameworks to address this novel class of environmental contaminants.

2025 Environmental Research and Ecotoxicity
Review Tier 2

Endocrine Toxicity of Micro- and Nanoplastics, and Advances in Detection Techniques for Human Tissues: A Comprehensive Review

This review summarizes growing evidence that micro- and nanoplastics contain or carry endocrine-disrupting chemicals that interfere with hormones throughout the body, triggering oxidative stress, inflammation, and cell death in hormone-producing tissues. The paper also reviews new detection methods that can identify and measure these tiny plastic particles in human blood, tissue, and other biological samples, which is essential for understanding real-world health impacts.

2025 Endocrines 10 citations
Article Tier 2

Microplastics: Environmental Occurrence and Analytical Challenges

This comprehensive literature review examines how microplastics — plastic particles between 1 micrometer and 5 mm — enter and move through ecosystems, and what analytical methods are used to detect them. Despite being found throughout the world, the environmental consequences and toxic effects of microplastics on living organisms are still not fully understood.

2022 Figshare 9 citations
Article Tier 2

Environmental prevalence, fate, impacts, and mitigation of microplastics—a critical review on present understanding and future research scope

This critical review evaluates the environmental prevalence, fate, impacts, and mitigation of microplastics across aquatic, atmospheric, and terrestrial environments as well as human tissues. It discusses membrane-based and other treatment technologies for microplastic removal, identifying persistent monitoring and standardization challenges.

2020 Environmental Science and Pollution Research 57 citations
Article Tier 2

Micro‐ and Nanoplastics—An Invisible Threat to Human Health

This review describes micro- and nanoplastics as an invisible threat to human health, examining how their small size and chemical complexity make them difficult to detect and assess. The authors call for better analytical tools, standardized methods, and expanded epidemiological research.

2024
Article Tier 2

The impact of microplastic pollution on human health - current issues

This review covers the sources, distribution, and ecological implications of microplastics in terrestrial, aquatic, and atmospheric environments, synthesizing existing knowledge and research gaps. It finds that MPs are a global contaminant threatening biodiversity and human health through chemical leaching, endocrine disruption, and physical harm to organisms at multiple trophic levels.

2025 Ecological Questions
Article Tier 2

Challenges and Recent Analytical Advances in Micro/Nanoplastic Detection

This review covers the challenges scientists face in detecting and measuring micro- and nanoplastics in the environment, especially for particles smaller than one micrometer. Current analytical methods have significant limitations for identifying nanoplastics due to their extremely small size and diverse chemical compositions. Improving detection technology is essential for accurately assessing how much microplastic contamination exists in water, food, and human tissues.

2024 Analytical Chemistry 41 citations
Article Tier 2

Microplastics as Emerging Contaminants: Investigating their Potential to Alter Human Metabolic and Endocrine Systems

This review investigated the potential of microplastics to alter human hormone signaling, synthesizing evidence that plastic particles and their chemical additives can act as endocrine disruptors at environmentally relevant concentrations. The paper highlighted reproductive and metabolic pathways as areas of particular concern.

2024
Article Tier 2

Methodologies to characterize, identify and quantify nano- and sub-micron sized plastics in relevant media for human exposure: a critical review

This review critically evaluated methodologies for characterizing, identifying, and quantifying nano- and sub-micron sized plastics in media relevant to human exposure, highlighting analytical gaps and the need for standardized approaches.

2022 Environmental Science Advances 27 citations
Article Tier 2

Microplastics in the environment: analytical chemistry methods, sorption materials, risks and sustainable solutions

This review covers the full picture of microplastic pollution, from how scientists detect and measure these particles to how they carry other pollutants and affect living organisms. The authors highlight that microplastics act as tiny sponges that absorb harmful chemicals like pharmaceuticals and pesticides, then release them inside organisms that ingest the particles. The review calls for more standardized testing methods and sustainable solutions to reduce both microplastic pollution and its risks to human health.

2024 Analytical and Bioanalytical Chemistry 15 citations
Article Tier 2

Chemical Analysis of Microplastics and Nanoplastics: Challenges, Advanced Methods, and Perspectives

This review covers the latest laboratory methods for detecting and measuring microplastics and nanoplastics in environmental samples like water, food, and air. Identifying these tiny particles is extremely challenging because they vary enormously in size, shape, and plastic type, and concentrations can differ by billions of times between samples. Better standardized detection methods are essential for accurately understanding how much microplastic humans are actually exposed to.

2021 Chemical Reviews 927 citations
Article Tier 2

Challenge for the detection of microplastics in the environment

This review examines the major challenges in detecting and quantifying microplastics across different environmental matrices, including sampling inconsistencies, contamination risks, and limitations of current analytical methods. Addressing these methodological challenges is essential for producing reliable data on microplastic pollution levels worldwide.

2019 Water Environment Research 192 citations
Article Tier 2

Problematic issues of the impact of microplastics on the human body and the environment: A review

This review covers the current state of knowledge on how microplastics -- highly resistant artificial polymers -- affect human health and the environment, summarizing contamination pathways, toxicological effects, and the challenges of their slow decomposition. The authors highlight significant knowledge gaps and call for better monitoring and regulatory frameworks to address the growing microplastic problem.

2024 Pediatrics Consilium Medicum
Article Tier 2

Microplastic pollution-A major health problem-An update

This review summarizes the current understanding of microplastic pollution as a health concern, covering how these tiny plastic particles enter the human body through inhalation and ingestion of contaminated food and beverages. The study discusses chemical additives found in plastics, including endocrine disruptors like bisphenol A and phthalates, which have been associated with various health effects. However, the authors note that the fate and effects of microplastics once inside the human body remain controversial and require further study.

2025 International Journal of Science and Research Archive 1 citations