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Methodologies to characterize, identify and quantify nano- and sub-micron sized plastics in relevant media for human exposure: a critical review
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This review critically evaluated methodologies for characterizing, identifying, and quantifying nano- and sub-micron sized plastics in media relevant to human exposure, highlighting analytical gaps and the need for standardized approaches.
Micro- and nanoplastics (MNPs) in the environment are an emerging issue of global concern.
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This critical review examines the current methods for detecting and characterizing micro- and nanoplastics in various environmental samples, as well as reported toxic effects from in vivo and in vitro studies. The authors found that while substantial effort has been made to understand microplastic behavior, the scientific community is still far from a complete understanding of how these particles behave in biological systems. The review calls for improved standardized protocols and more studies focused on uptake kinetics, accumulation, and biodistribution.
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This review systematically summarizes detection and characterization methods for micro-, submicron-, and nanoplastics, providing recommendations for method validation, standardization, and analytical pathways suited to different sample types and research goals.
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