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61,005 resultsShowing papers similar to Digestive enzyme-driven desorption of phenanthrene from microplastics in a simulated human gut
ClearThe adsorption and desorption behaviors of phenanthrene and pyrene onto microplastics in the aquatic environment and digestive fluids
This study examined how polycyclic aromatic hydrocarbons (PAHs) like phenanthrene and pyrene adsorb to and desorb from four types of microplastics in both freshwater and simulated digestive fluids. The findings show that PAHs bind strongly to microplastics and can be released under digestive conditions, suggesting that microplastics can deliver organic pollutants to organisms that ingest them.
Microplastics-sorbed phenanthrene and its derivatives are highly bioaccessible and may induce human cancer risks
Researchers studied how microplastics sorb phenanthrene and its derivatives, then measured the bioaccessibility and potential cancer risk of these contaminant-laden particles. The study found that microplastic-sorbed polycyclic aromatic hydrocarbons were highly bioaccessible during simulated digestion, suggesting they may pose meaningful human health risks when ingested.
Desorption of Polycyclic Aromatic Hydrocarbons from Microplastics in Human Gastrointestinal Fluid Simulants─Implications for Exposure Assessment
Scientists used a lab model of the human digestive system to study how cancer-causing chemicals called PAHs are released from microplastics as they pass through the gut. They found that 21-29% of the chemicals absorbed onto microplastics were released during digestion, with the most release happening in the intestines. However, the overall contribution of microplastic-carried PAHs to total dietary intake was very low, suggesting that for most people, microplastics are not a major source of PAH exposure through food.
How Digestive Processes Can Affect the Bioavailability of PCBs Associated with Microplastics: A Modeling Study Supported by Empirical Data
Researchers used a simulated human digestive model to study whether gut processes change how quickly chemicals like PCBs transfer on and off microplastic particles. They found that digestive enzymes and bile salts significantly accelerated the release of these chemicals from microplastics, suggesting that the human gut environment may increase exposure to plastic-associated pollutants. The study provides new evidence that microplastics could act as carriers that release harmful chemicals more readily during digestion.
Exposure to microplastic associated chemicals upon oral consumption of microplastics
This thesis quantified the release of plastic-associated chemical contaminants from microplastics during simulated human digestion, measuring how much of these chemicals actually leach out under stomach and intestinal conditions. The research helps estimate the chemical exposure humans receive when they ingest microplastics through food and water.
Desorption of bisphenol A from microplastics under simulated gastrointestinal conditions
Researchers investigated bisphenol A desorption from three types of microplastics under simulated gastrointestinal conditions, finding that ingested microplastics can release adsorbed BPA during digestion, posing potential health risks.
Digestion of plastics using in vitro human gastrointestinal tract and their potential to adsorb emerging organic pollutants
Researchers simulated human digestion of polystyrene and polyethylene plastics and found that digestive processes fundamentally altered plastic surfaces, creating new functional groups and generating micro- and nanostructures that can detach. The study suggests that digested plastics have enhanced capacity to adsorb certain pollutants like triclosan and diclofenac, potentially increasing health risks from ingested plastic.
Adsorption of 2-hydroxynaphthalene, naphthalene, phenanthrene, and pyrene by polyvinyl chloride microplastics in water and their bioaccessibility under in vitro human gastrointestinal system
Researchers studied how polyvinyl chloride microplastics adsorb organic pollutants including naphthalene and pyrene, and then tested how these pollutants are released in simulated human digestive fluids. The study found that larger aromatic compounds with more rings adsorbed more strongly to microplastics, and that pollutant release rates were higher in human gastrointestinal fluid than in fish intestinal fluid.
Microplastics serve as a potential vector for the transfer of naphthalene from freshwater to the human gastrointestinal system
Researchers investigated whether microplastics can transfer the pollutant naphthalene from freshwater into the human gastrointestinal system. The study examined three types of microplastics and found they can adsorb naphthalene from water and subsequently release it under simulated digestive conditions, suggesting microplastics may act as vectors that carry environmental contaminants into the human body through ingested water or food.
Pollutant adsorption on microplastic and its release during digestion processes
Researchers investigated the adsorption of copper and PFAS onto polystyrene, polypropylene, and polyethylene microplastics and examined the subsequent release of these contaminants during simulated digestion processes. The study aimed to clarify the role of microplastics as vectors that increase contaminant bioavailability in marine biota.
In vitro digestion of microplastics in human digestive system: Insights into particle morphological changes and chemical leaching
Researchers simulated human digestion on four common types of microplastics and found that stomach acid and digestive enzymes changed the particles' shape, surface texture, and caused them to release chemical additives. The study shows that microplastics are not inert once swallowed -- they are actively transformed in the gut, which could increase their ability to interact with intestinal tissues and release potentially harmful chemicals.
Pollutant adsorption on microplastic and its release during digestion processes
Researchers investigated how microplastics act as contaminant vectors for copper and PFAS by adsorbing these substances onto polystyrene, polypropylene, and polyethylene particles and then evaluating their release under simulated gastrointestinal conditions using the Infogest static digestion protocol. They compared adsorption and release across polymer types and particle morphologies (spherical microbeads vs. post-consumer irregular microplastics) to assess how pH, enzymes, and bile affect desorption of these contaminants.
Investigating the desorption of polybrominated diphenyl ethers from polyethylene microplastics to sediment
Researchers investigated how polybrominated diphenyl ethers (PBDEs) desorb from polyethylene microplastics under simulated gut conditions, finding that digestive fluids with surfactants significantly enhanced PBDE release, raising concerns about gut-mediated transfer of flame retardants from ingested plastic particles.
Adsorption mechanism of cadmium on microplastics and their desorption behavior in sediment and gut environments: The roles of water pH, lead ions, natural organic matter and phenanthrene
Researchers compared how cadmium adsorbs onto five different microplastic types and then desorbs in simulated sediment and gut environments, finding that pH, competing ions, natural organic matter, and co-pollutants like phenanthrene all significantly alter how much cadmium is released.
Different partition of polycyclic aromatic hydrocarbon on environmental particulates in freshwater: Microplastics in comparison to natural sediment
This study investigated how the polycyclic aromatic hydrocarbon phenanthrene partitions between water and three common plastic types, finding that polymer composition strongly influences sorption behavior. The results help explain how microplastics act as vectors for toxic organic compounds in aquatic environments.
The influence of digestive tract protein on cytotoxicity of polyvinyl chloride microplastics
This study examined how human digestive enzymes change the properties of PVC microplastics as they pass through a simulated digestive tract. After digestion, the microplastics became more water-friendly and mobile in the body, and they caused greater damage to intestinal cells, including reduced cell survival, increased oxidative stress, and disrupted energy metabolism. These findings suggest that the digestion process itself may make microplastics more harmful to the human gut than previously assumed.
Study of the scavenger and vector roles of microplastics for polyhalocarbazoles under simulated gastric fluid conditions
Researchers studied the desorption kinetics of polyhalocarbazoles from polypropylene and polyvinyl chloride microplastics under simulated gastric conditions for both vertebrates and invertebrates, finding rapid initial release followed by slow ongoing transfer over weeks to months. Smaller microplastic particles and invertebrate digestive conditions enhanced desorption, confirming that microplastics can act as vectors for these halogenated contaminants in the gut.
Microplastics as benzo-a-pyrene carriers: genotoxicity assessment simulating human gastric digestion
This study tested whether microplastics can carry the cancer-causing chemical benzo[a]pyrene into the body during digestion, using a simulation of human stomach conditions. The researchers found that microplastics did act as carriers for this harmful pollutant and caused DNA damage in cells. This suggests that swallowing microplastics contaminated with toxic chemicals could increase health risks beyond what the plastic particles alone would cause.
Sorption behaviors of crude oil on polyethylene microplastics in seawater and digestive tract under simulated real-world conditions
Polyethylene microplastics can absorb crude oil from seawater, and once ingested by aquatic organisms, some of that oil can be released in simulated gut conditions. This suggests microplastics could act as vectors that concentrate and deliver toxic hydrocarbons to marine life.
Bioaccessibility of Trace Metals and Rare Earth Elements (REE) in Microplastic
Researchers measured the bioaccessibility of trace metals and rare earth elements adsorbed onto beach microplastics using simulated digestive fluid conditions. Metals were released from microplastic surfaces under stomach acid conditions, indicating that plastic ingestion can deliver these contaminants to digestive systems of marine organisms and humans.
Key Physicochemical Properties Dictating Gastrointestinal Bioaccessibility of Microplastics-Associated Organic Xenobiotics: Insights from a Deep Learning Approach
A deep learning analysis of gastrointestinal bioaccessibility data for 18 microplastic types found that polymer structural rigidity and surface area were the key physicochemical properties controlling desorption of pyrene and 4-nonylphenol under digestive conditions, covering a bioaccessibility range of 16–83% across polymer types.
PET Microplastics Affect Human Gut Microbiota Communities During Simulated Gastrointestinal Digestion. First Evidence of Plausible Polymer Biodegradation During Human Digestion
Researchers simulated gastrointestinal digestion and found that PET microplastics altered human gut microbiota community composition, and provided first evidence of plausible partial polymer biodegradation during passage through the human digestive tract.
Microplastics in our diet: complementary in vitro gut and epithelium models to understand their fate in the human digestive tract.
Researchers used complementary in vitro gut models to study how microplastics behave during human digestion, finding that digestive conditions alter microplastic surface properties and their interactions with gut cells. The work advances understanding of how ingested microplastics may affect the human digestive system.
Adsorption of progesterone onto microplastics and its desorption in simulated gastric and intestinal fluids
Progesterone adsorbed readily to polyethylene, polypropylene, and polystyrene microplastics (up to 357 µg/g), and desorption experiments in simulated gastric and intestinal fluids showed substantial release under digestive conditions, suggesting a pathway for hormonal contaminant transfer via ingested MPs.