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Adsorption of progesterone onto microplastics and its desorption in simulated gastric and intestinal fluids

Environmental Science Processes & Impacts 2021 41 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 50 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.

Yang Liu, Yang Liu, Yang Liu, Yang Liu, Yang Liu, Yang Liu, Yang Liu, Yang Liu, Yang Liu, Cécilia Laetitia Carla Siri, Cécilia Laetitia Carla Siri, William Dudefoi, William Dudefoi, Thibault Masset, Yang Liu, Yang Liu, Yang Liu, Yang Liu, Yang Liu, Florian Breider Yang Liu, Florian Breider Yang Liu, Yang Liu, Florian Breider Florian Breider Yang Liu, Yang Liu, Yang Liu, Yang Liu, Thibault Masset, Thibault Masset, Thibault Masset, Cécilia Laetitia Carla Siri, Thibault Masset, Thibault Masset, Thibault Masset, Thibault Masset, Thibault Masset, Florian Breider Dean Oldham, Florian Breider Thibault Masset, Florian Breider William Dudefoi, Yang Liu, William Dudefoi, Yang Liu, Thibault Masset, Thibault Masset, Thibault Masset, Yang Liu, Florian Breider Florian Breider Yang Liu, Florian Breider Florian Breider Yang Liu, Florian Breider Thibault Masset, Thibault Masset, William Dudefoi, Florian Breider Thibault Masset, Thibault Masset, Yang Liu, Yang Liu, Florian Breider William Dudefoi, William Dudefoi, Dean Oldham, Yang Liu, Florian Breider Florian Breider Florian Breider Yang Liu, Matteo Minghetti, Matteo Minghetti, Matteo Minghetti, Matteo Minghetti, Yang Liu, Florian Breider Yang Liu, Florian Breider Florian Breider Yang Liu, Yang Liu, William Dudefoi, Dominique Grandjean, Dominique Grandjean, Yang Liu, Yang Liu, Yang Liu, Florian Breider Matteo Minghetti, Dominique Grandjean, Florian Breider Florian Breider Florian Breider Florian Breider Matteo Minghetti, Matteo Minghetti, Florian Breider

Summary

Progesterone adsorbed readily to polyethylene, polypropylene, and polystyrene microplastics (up to 357 µg/g), and desorption experiments in simulated gastric and intestinal fluids showed substantial release under digestive conditions, suggesting a pathway for hormonal contaminant transfer via ingested MPs.

Polymers

PE PP PS

Body Systems

Digestive

The sorption of hydrophobic organic compounds (HOC) onto microplastics is relatively well reported in the literature, while their desorption remains poorly investigated, especially in biological fluids. The present study investigated the sorption and desorption of progesterone on polyethylene (PE), polypropylene (PP), and polystyrene (PS) microplastics. The sorption experiments showed that the equilibrium was reached in a few hours for all plastics. A sorption efficiency of 357.1 μg g-1 was found for PE and PS, and 322.6 μg g-1 for PP. Sorption experiments indicated that adsorption would certainly happen via surface sorption and a potentially pore-filling mechanism. The desorption was carried out in Simulated Gastric Fluid (SGF) and Simulated Intestinal Fluid (SIF), whose formulations were more complex than similar models reported so far. It has been found that the desorption was higher in SIF as compared to SGF, due to micelle formation in SIF promoting the pollutant solubilization. The sorption of pepsin onto microplastics has also been revealed, suggesting a competition between pollutants and pepsin for sorption sites and a potent reduction in pollutant solubilization. This study indicates that the ingestion of microplastics could be considered as an additional route of exposure to pollutants and therefore emphasizes pollutant bioavailability for aquatic organisms.

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