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20 resultsShowing papers similar to New evidence of the presence of micro- and nanoplastic particles in bronchioalveolar lavage samples of clinical trial subjects
ClearFirst evidence of microplastics isolated in European citizens’ lower airway
Researchers provided the first evidence of microplastics in the lower airways of living European adults, using bronchoalveolar lavage fluid from 44 patients. Nearly all detected particles were microfibers averaging about 1.7 millimeters in length, with an average concentration of roughly 9 items per 100 milliliters of fluid. The findings confirm that microplastics reach deep into the human respiratory system, though the health implications require further investigation.
Detection of Microplastics in Human Bronchoalveolar Lavage Fluid: Preliminary Evidence of Respiratory Exposure to Environmental Contaminants
Researchers analyzed bronchoalveolar lavage fluid from eight adult patients undergoing diagnostic bronchoscopy and detected microplastics in the samples using microscopy, providing preliminary direct evidence that airborne microplastics deposit in the human respiratory tract.
Presence of microplastics in human’s respiratory system: bronchoalveolar and bronchial lavage fluid
Researchers analyzed bronchial and bronchoalveolar lavage fluid from patients undergoing bronchoscopy and confirmed the presence of microplastics in the human respiratory system. They characterized the types, sizes, and quantities of microplastic particles found at different levels of the airways. The study provides direct evidence that microplastics deposit within human lungs and suggests that respiratory exposure is a meaningful route of human microplastic intake.
Presence of airborne microplastics in human lung tissue
Researchers examined human lung tissue from autopsies and found microplastic particles and fibers in 13 out of 20 samples. The most common plastics were polyethylene and polypropylene, with particles smaller than 5.5 micrometers. This study provides direct evidence that inhaled microplastics accumulate in human lungs, raising concerns about potential long-term effects on respiratory health.
Microplastics inhalation: evidence in human lung tissue
Microplastic particles were found in human lung tissue samples collected during surgery, confirming that people inhale and retain microplastics in pulmonary tissue, with polypropylene and polyethylene terephthalate among the polymers identified, raising concerns about chronic respiratory and inflammatory effects.
Detection and Analysis of Microplastics in Human Sputum
Researchers analyzed sputum (mucus from the lungs) from 22 patients with respiratory diseases and found microplastics in every single sample, identifying 21 different plastic types. Polyurethane was the most common type detected, and most particles were smaller than 500 micrometers. This study provides direct evidence that humans are inhaling microplastics, with factors like smoking and medical procedures increasing the amount found in the respiratory tract.
Isolation and characterization of microplastics from the human respiratory system: Sputum, broncho-alveolar lavage fluid, and pleural fluid simultaneously
In the first study of its kind in Iran, researchers found microplastics in every sample collected from the human respiratory system, including sputum, lung fluid, and the fluid surrounding the lungs. Polyester fibers were the most common type detected, and people with occupational exposure or smoking habits had higher amounts, confirming that we regularly breathe in microplastics that reach deep into our lungs.
Human Exposure to Airborne Microplastics: A Study on Detection and Potential Health Effects Using BAL Fluid
This study detected inhaled microplastics in bronchoalveolar lavage fluid from the lower respiratory tract of human patients and found associations between microplastic presence and markers of lung inflammation and impaired lung function.
Nanoplastics in the Human Respiratory System
This research paper reports on the detection and characterization of nanoplastics in the human respiratory system, published in a leading pulmonary medicine journal. The study adds to growing evidence that extremely small plastic particles are present in human lungs. The findings underscore the importance of understanding inhalation as a key route of human exposure to plastic pollution.
Bronchoalveolar Lavage as a Diagnostic Window into Human Exposure to Microplastics and Associated Lung Changes
Bronchoalveolar lavage analysis revealed microplastics in the lower respiratory tract of human patients and showed associated inflammatory changes, providing direct evidence of pulmonary microplastic exposure and supporting the need for occupational and environmental health monitoring.
Microplastics in Human Bronchoalveolar Lavage Fluid
Researchers developed a new method for detecting microplastics in fluid washed from human lungs (bronchoalveolar lavage fluid) and found plastic particles present in every patient tested. They also applied Nile Red staining for the first time to visualize plastics in lung samples, which proved effective for screening and counting particles. The findings provide direct evidence that microplastics are present in the human respiratory system, with a potential link to lung inflammation.
Microplastics in Human Bronchoalveolar Lavage Fluid
Researchers developed a method to detect microplastics in bronchoalveolar lavage fluid, a less invasive sampling technique than surgical lung biopsy, to assess human respiratory exposure. Using fluorescence microscopy and Raman spectroscopy, they identified and characterized microplastic particles in lung wash samples from patients undergoing bronchoscopy. The study suggests that lavage fluid analysis could become a practical tool for monitoring microplastic exposure in human lungs.
Detection of microplastics in human nasal mucosa
Microplastic particles were detected for the first time in human nasal mucosa samples, with polymer types and concentrations quantified, providing direct evidence that the upper respiratory tract is a site of microplastic deposition from inhaled air.
Assessment of background plastics contamination from human respiratory tract sample collection vessels
Researchers found that disposable plastic collection vessels used in bronchoalveolar lavage and transbronchial aspiration procedures can contaminate respiratory tract samples with microplastic particles, highlighting the need for blank controls and low-plastic equipment in human inhalation studies.
New Evidence of Microplastics in the Lower Respiratory Tract: Inhalation through Smoking
Researchers collected lung fluid samples from smokers and nonsmokers and found that smokers had significantly higher concentrations of microplastics in their lower respiratory tract. A laboratory smoking simulation confirmed that cigarette smoke itself carries microplastic particles, including polyurethane and silicone. The study identifies smoking as a previously unrecognized route of microplastic inhalation, adding to the known health concerns associated with tobacco use.
Tracing Microplastics in the Human Body: From Detection to Disease Mechanisms
This review traces the detection of microplastics across multiple human tissues — from nasal lavage and bronchoalveolar fluid to blood and lung tissue — and examines the disease mechanisms linking plastic particle accumulation to respiratory, cardiovascular, and other systemic health effects.
Temporal Trend in Accumulation of Microplastics in Decedent Human Lungs
Researchers compared lung tissue samples from people who died in 1991 and 2024 and found that microplastic presence increased from 19% to 77% of individuals over that period, with the number of particles per gram of tissue also rising significantly. The polymer composition shifted from predominantly polyethylene to a more diverse mix including PET and PVC, and lung samples containing microplastics showed greater signs of inflammation and fibrosis.
Airborne microplastics: Consequences to human health?
Researchers reviewed existing evidence on airborne microplastics and their potential effects on human respiratory health. Studies of workers exposed to plastic fibers and particles have documented airway inflammation and breathing difficulties, suggesting that susceptible individuals may face health risks even from environmental concentrations. The paper calls for greater awareness and future research into the health consequences of inhaling microplastic particles.
A systematic review of the effects of airborne microplastic contamination on human lungs
This systematic review summarizes research showing that airborne microplastics have a negative effect on human lungs. Humans are estimated to inhale roughly 100,000 fine plastic particles every day, and the evidence suggests this exposure contributes to respiratory health problems, underscoring the need for policies to reduce plastic pollution in the air we breathe.
Impact of Airborne Microplastics on Induced Sputum of Urban Dwellers: the Role of Environmental and Occupational Factors
Researchers analyzed induced sputum samples from 25 patients with respiratory diseases and found microplastics present in all samples, with concentrations ranging from 6 to 500 particles per 100 mL. Active smokers and workers in occupations with high plastic exposure had significantly higher microplastic concentrations. The study suggests that airborne microplastic inhalation is widespread among urban residents and may be influenced by both lifestyle and occupational factors.