Papers

20 results
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Article Tier 2

Anti-oxidant and anti-apoptotic effects of royal jelly against polystyrene microplastic-induced testicular injury in mice.

Royal jelly — a natural bee product — protected mouse testes from damage caused by polystyrene microplastic exposure by boosting antioxidant defenses and reducing programmed cell death. This points to potential protective nutritional strategies against reproductive harm from microplastic ingestion, though results in mice need to be verified before drawing conclusions about human health.

2024 PubMed 3 citations
Article Tier 2

Oxidative Stress and Male Fertility: Promising Role of Nutraceuticals

This paper is not about microplastics; it reviews the role of oxidative stress in male infertility and the potential of nutraceuticals (antioxidant-rich dietary supplements) to improve sperm quality and hormonal profiles, with no connection to microplastic research.

2023 Biochemistry 2 citations
Article Tier 2

Dual-Stress Mitigation of Sclerotinia under Microplastic Toxicity by Nano-Selenium: Redox Balance, Pathogen Suppression, and Transcriptome Reprogramming

Researchers investigated whether selenium nanoparticles could protect rapeseed plants from combined stress caused by microplastics and the fungal pathogen Sclerotinia. The study found that selenium nanoparticles improved photosynthesis, reduced oxidative damage, and showed strong antifungal activity, suggesting they may help mitigate microplastic-induced phytotoxicity and fungal disease in agricultural settings.

2025 Journal of Agricultural and Food Chemistry 1 citations
Article Tier 2

Evaluating Silymarin Extract as a Potent Antioxidant Supplement in Diazinon-Exposed Rainbow Trout: Oxidative Stress and Biochemical Parameter Analysis

This study tested whether silymarin, a natural antioxidant from milk thistle, could protect rainbow trout from liver damage caused by the pesticide diazinon. Silymarin successfully reduced oxidative stress and restored many blood markers to normal levels in the exposed fish. While not directly about microplastics, the research is relevant because microplastics in water can carry pesticides like diazinon, and understanding protective compounds could help address the combined toxic effects of these pollutants on aquatic food sources.

2023 Toxics 52 citations
Article Tier 2

Nano-selenium ameliorates microplastics-induced injury: Histology, antioxidant capacity, immunity and intestinal microbiota of grass carp (Ctenopharyngodon idella)

Researchers tested whether nano-selenium supplements could protect grass carp from damage caused by polystyrene microplastics. They found that nano-selenium reduced the tissue damage, oxidative stress, and immune suppression caused by microplastic exposure, and helped restore healthy gut bacteria. The study suggests that dietary nano-selenium may be a practical strategy for protecting farmed fish from the harmful effects of microplastic pollution in aquatic environments.

2024 Ecotoxicology and Environmental Safety 9 citations
Article Tier 2

Dual-Stress Mitigationof Sclerotinia under MicroplasticToxicity by Nano-Selenium: Redox Balance, Pathogen Suppression, andTranscriptome Reprogramming

Researchers tested whether selenium nanoparticles (SeNPs) could protect rapeseed plants from the combined stress of microplastic contamination and Sclerotinia sclerotiorum fungal infection. SeNPs improved seed germination, reduced oxidative damage, and altered gene expression to restore redox balance — largely reversing the dual stress effects.

2025 Figshare
Article Tier 2

Alteration in the Antioxidant Enzymes Activities as Potential Biomarkers for Identification of Stress Caused by Afidopyropen Intoxication in Cyprinus Carpio.

This paper is not relevant to microplastics research — it studies oxidative stress biomarkers in common carp (Cyprinus carpio) exposed to afidopyropen, a synthetic insecticide, with no connection to plastic pollution.

2023 Current World Environment
Article Tier 2

Attenuative effect of astilbin on polystyrene microplastics induced testicular damage: Biochemical, spermatological and histopathological-based evidences

Researchers found that astilbin, a natural plant compound, significantly reduced testicular damage caused by polystyrene microplastic exposure in rats. The microplastics disrupted hormone levels, sperm quality, and testicular tissue structure, but astilbin treatment counteracted these effects by boosting antioxidant defenses and reducing inflammation. The study suggests that natural antioxidant compounds may offer protective benefits against the reproductive harm associated with microplastic exposure.

2023 Toxicology and Applied Pharmacology 23 citations
Article Tier 2

Selenium alleviates the adverse effects of microplastics on kale by regulating photosynthesis, redox homeostasis, secondary metabolism and hormones

Researchers found that treating soil with selenium could protect kale plants from the harmful effects of microplastic contamination. Microplastics triggered damaging oxidative stress in the plants, but selenium helped restore the balance by boosting antioxidant defenses, improving photosynthesis, and regulating plant hormones. This suggests selenium supplementation could help maintain food crop health in microplastic-contaminated agricultural soils.

2024 Food Chemistry 30 citations
Article Tier 2

Pharmacotherapeutic potential of ginkgetin against polystyrene microplastics–instigated testicular toxicity in rats: A biochemical, spermatological, and histopathological assessment

In a rat study, polystyrene microplastics caused significant damage to the testes, including reduced sperm quality, oxidative stress, and tissue inflammation, but the natural plant compound ginkgetin was able to partially reverse this damage. Ginkgetin worked by boosting antioxidant defenses and reducing the inflammatory response triggered by the microplastics. This suggests that natural antioxidant compounds might help protect male reproductive health from the harmful effects of microplastic exposure.

2024 Environmental Science and Pollution Research 13 citations
Article Tier 2

Captivating Colors, Crucial Roles: Astaxanthin’s Antioxidant Impact on Fish Oxidative Stress and Reproductive Performance

This review examines how the antioxidant astaxanthin can protect fish from oxidative stress and improve their reproductive health in aquaculture settings. While not directly about microplastics, the research is relevant because microplastic exposure causes oxidative stress in fish, and antioxidants like astaxanthin could help mitigate that damage. Understanding these protective mechanisms may be important for maintaining the health and safety of farmed fish destined for human consumption.

2023 Animals 50 citations
Article Tier 2

Selenium-driven trophic restructuring of soil nematode communities and biochemical regulation alleviate the toxicity caused by microplastic pollution in highland barley

Researchers investigated whether selenium supplementation could counteract the harmful effects of polyethylene microplastics on highland barley and soil nematode communities. They found that microplastics significantly reduced plant growth metrics and disrupted nematode populations, but selenium application helped restore chlorophyll content, root development, and beneficial soil organism diversity. The study suggests that selenium may serve as a practical tool for mitigating microplastic-induced damage in agricultural soils.

2026 Ecotoxicology and Environmental Safety
Article Tier 2

Effects of inorganic and organic selenium intervention on resistance of radish to arsenic stress

Researchers studied how organic and inorganic selenium supplements affect arsenic uptake in radish plants under arsenic stress conditions. They found that organic selenium was more effective than inorganic selenium at reducing arsenic absorption and improving the plants' antioxidant defenses. While not directly about microplastics, the study contributes to understanding how soil amendments can help crops resist environmental contaminant stress.

2022 Italian Journal of Food Science 55 citations
Article Tier 2

Emerging insights into the impacts of heavy metals exposure on health, reproductive and productive performance of livestock

This review examines how heavy metals like lead, mercury, and cadmium accumulate in livestock through contaminated feed and water, causing oxidative stress, organ damage, reproductive problems, and reduced productivity. While focused on livestock rather than microplastics, the paper is relevant because microplastics can carry and concentrate heavy metals, potentially making their combined effects on the food chain even worse.

2024 Frontiers in Pharmacology 79 citations
Article Tier 2

Microplastics in ovarian function and ozone-based mitigation strategies: Emerging evidence and translational implications

This review synthesized emerging evidence that microplastics accumulate in human follicular fluid, oocytes, placenta, and semen, causing oxidative stress, mitochondrial dysfunction, and meiotic disruption in reproductive cells, and discussed ozone-based strategies as potential mitigation approaches.

2025 Current Research in Toxicology
Article Tier 2

Revealing the Selenium-Mediated Regulatory Mechanisms of P. stratiotes in Response to Nanoplastics Stress from Multiple Perspectives of Transcriptomics, Metabolomics, and Plant Physiology

Scientists found that tiny plastic particles (nanoplastics) seriously damage water plants by disrupting their ability to make food from sunlight and causing harmful stress inside their cells. However, when researchers added selenium (a natural mineral) to the water, it helped protect the plants from plastic damage by boosting their natural defense systems. This research could help us clean up plastic pollution in lakes and rivers, which is important since these water sources can affect human health through drinking water and food chains.

2026 Toxics
Article Tier 2

Optimization of Green Synthesis of Selenium Nanoparticles and Evaluation of Their Antifungal Activity against Oral Candida albicans Infection

This study focused on optimizing the green synthesis of selenium nanoparticles and evaluating their antifungal activity against oral Candida albicans. While not directly related to microplastics research, the work contributes to the broader field of nanomaterial characterization and biological effects of nano-scale particles.

2022 Advances in Materials Science and Engineering 43 citations
Article Tier 2

Determination of Biological and Molecular Attributes Related to Polystyrene Microplastic-Induced Reproductive Toxicity and Its Reversibility in Male Mice

Researchers exposed male mice to polystyrene microplastics through drinking water and found that the particles caused mitochondrial damage in testicular tissue, including reduced membrane potential and disrupted energy production. This mitochondrial dysfunction led to decreased sperm quality, likely driven by oxidative stress. Importantly, the study found that sperm quality recovered after one to two spermatogenic cycles without further exposure, suggesting that reproductive toxicity from microplastics may be reversible.

2022 International Journal of Environmental Research and Public Health 42 citations
Article Tier 2

Microplastic-induced NAFLD: Hepatoprotective effects of nanosized selenium

This study found that polystyrene microplastics caused nonalcoholic fatty liver disease in mice by disrupting fat metabolism and triggering oxidative stress, but selenium nanoparticles derived from a yak-sourced bacterium significantly prevented this damage. The microplastics suppressed two key protective pathways in the liver, while the selenium nanoparticles activated those same pathways to counteract the harm. These findings suggest that microplastic exposure may contribute to liver disease in humans and point to selenium-based supplements as a potential protective strategy.

2024 Ecotoxicology and Environmental Safety 18 citations
Article Tier 2

Impact of polystyrene microplastic exposure at low doses on male fertility: an experimental study in rats

Researchers exposed adult male rats to varying doses of polystyrene microplastics and found dose-dependent declines in semen quality along with disrupted reproductive hormone levels. Higher doses caused increased oxidative stress, mitochondrial damage, and inflammatory responses in testicular tissue. The study suggests that even relatively low doses of microplastic exposure may have adverse effects on male reproductive health in animal models.

2026 Scientific Reports