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61,005 resultsShowing papers similar to Unravelling protein corona formation on pristine and leached microplastics
ClearUnravelling protein corona formation on pristine and leached microplastics
Researchers found that when microplastics encounter proteins in biological fluids, they get coated in a "protein corona" that depends heavily on the plastic's chemical additives, surface area, and how much it has been weathered in the environment. This coating changes how microplastics behave in the body, meaning toxicity studies need to account for these real-world surface changes.
Role of the Protein Corona in the Colloidal Behavior of Microplastics
Researchers investigated how protein coronas form on polyethylene and polypropylene microplastics in biological media, finding that proteins act as surfactants that alter the colloidal behavior and stability of microplastics in aquatic environments.
Nanoplastics and Protein Corona - Investigating the Corona Structure and their Biological Impacts
This PhD thesis investigated how proteins from biological fluids coat the surface of nanoplastics, forming a 'protein corona' that changes how nanoplastics interact with cells and tissues. The protein corona is important because it alters the biological behavior of nanoplastics once they enter the body, potentially affecting how harmful they are.
Coronas of micro/nano plastics: a key determinant in their risk assessments
This review examines how micro- and nanoplastics develop surface coatings called coronas when they interact with biological and environmental substances. These corona layers, formed from proteins, organic matter, and other materials, can significantly change how plastic particles behave in the body and environment, affecting their uptake, distribution, and toxicity. The study suggests that understanding these surface coatings is essential for accurately assessing the real-world risks of plastic particle exposure.
Protein corona as a mediator in antibiotic adsorption onto microplastics: Mechanisms and implications
Researchers investigated how protein coronas that form on microplastic surfaces mediate the adsorption of antibiotics in environmental settings. The study provides direct evidence that biological molecules on microplastics facilitate chemical interactions with antibiotics, creating complexes that may pose risks to human health through environmental exposure pathways.
The interaction of micro/nano plastics and the environment: Effects of ecological corona on the toxicity to aquatic organisms.
This review examines how the ecological corona — the layer of organic matter, proteins, and microbes that form on micro- and nanoplastic surfaces in water — affects their toxicity to aquatic organisms. The ecological corona can either increase or decrease toxicity depending on its composition, making real-world plastic hazard assessment more complex than laboratory tests with clean particles suggest.
The Composition of the Eco-corona Acquired by Micro- and Nanoscale Plastics Impacts on their Ecotoxicity and Interactions with Co-pollutants
This review examines how the 'eco-corona' — a layer of environmental biomolecules adsorbing onto plastic particle surfaces — alters the toxicity, transport, and interaction with co-pollutants of micro- and nanoplastics, emphasizing that this biological coating fundamentally changes how plastics behave in living organisms.
Ecotoxicological significance of bio-corona formation on micro/nanoplastics in aquatic organisms
This review examined the ecotoxicological significance of bio-corona formation on micro- and nanoplastics in aquatic organisms, exploring how protein and biomolecule coatings alter the bioavailability, toxicity, and environmental fate of plastic particles.
Protein Corona Stability and Removal from PET Microplastics: Analytical and Spectroscopic Evaluation in Simulated Intestinal Conditions
Researchers studied how proteins from intestinal fluids form a coating, called a corona, on PET microplastics and how stable that coating is under different cleaning treatments. They found that the protein corona is highly persistent and resists oxidative and surfactant treatments, with only a combined alkaline-surfactant protocol effectively removing it. The findings are important because protein coatings on microplastics can alter how the particles interact with biological tissues and may affect the accuracy of analytical detection methods.
Strong binding between nanoplastic and bacterial proteins facilitates protein corona formation and reduces nanoplastics toxicity
Researchers demonstrated that bacteria-derived proteins adsorb strongly onto nanoplastic surfaces to form a 'protein corona,' altering nanoplastic morphology and reducing their toxicity to bacterial cells — with the degree of protection varying by surface chemistry, as amino-modified nanoplastics showed the greatest reduction in oxidative damage after corona formation.
Predicting Protein Corona Formation on Polylactic Acid Microplastics Pre- and Post-Photoaging: The Importance of Optimal Imputation Methods
Researchers used machine learning to predict which proteins from human blood plasma attach to polylactic acid microplastics, both before and after the plastics are aged by sunlight. They found that a protein's shape and surface area were key factors determining whether it would stick to the plastic, and that UV aging changed how certain amino acids interacted with the particle surface. The study highlights the importance of understanding how the body's proteins coat microplastics, since this protein layer influences how the particles behave inside biological systems.
Unraveling the interfacial fate of nanoplastics in soil: proteomics and molecular dynamics decipher the protein corona governed by surface functionalization
This study used proteomics and molecular dynamics simulations to examine how soil proteins coat nanoplastics — forming what is called a 'protein corona' — and how that coating changes depending on the nanoplastic's surface chemistry. The protein corona affects how nanoplastics move through soil and interact with living organisms, making this research important for understanding the true environmental fate of nanoplastics once they enter land ecosystems.
Protein Microplastic Coronation Complexes Trigger Proteome Changes in Brain-Derived Neuronal and Glial Cells
Researchers used a proteomics approach to study how microplastics interact with brain-derived neuronal and glial cells, finding that the particles adsorb proteins from biological fluids to form a coating called a protein corona. This corona significantly altered protein expression in cells compared to bare microplastic particles, affecting protein synthesis, lipid metabolism, and cellular transport processes. The study suggests that the protein corona on microplastics may play a key role in how these particles affect brain cells.
Toxicity of micro/nanoplastics in the environment: Roles of plastisphere and eco-corona
This review examines how microplastics and nanoplastics gain biological coatings in the environment: larger microplastics develop a "plastisphere" of microorganisms on their surface, while smaller nanoplastics get wrapped in proteins and organic matter forming an "eco-corona." Both coatings change how toxic the particles are to living organisms and humans. The review highlights that studying plastic particles without these coatings, as most lab experiments do, may underestimate or mischaracterize their real-world health risks.
Fate of polystyrene micro- and nanoplastics in zebrafish liver cells: Influence of protein corona on transport, oxidative stress, and glycolipid metabolism
Scientists studied how proteins in biological fluids coat nanoplastic particles (forming a "protein corona") and how this coating changes the way cells take up and process the plastics. The protein coating actually increased how many nanoplastics entered liver cells and made them harder to clear out, suggesting that once nanoplastics enter the bloodstream, the body's own proteins may make the contamination harder to eliminate.
Protein Corona Stability and Removal from PET Microplastics: Analytical and Spectroscopic Evaluation in Simulated Intestinal Conditions
Researchers studied how proteins in the gut environment attach to PET microplastics and found that a persistent protein coating, called a corona, forms quickly and resists simple cleaning methods. Only specific combinations of oxidation with alkaline or surfactant treatments could effectively remove the protein layer without damaging the plastic itself. The findings are important because protein coronas change how microplastics interact with biological systems and can interfere with accurately detecting and analyzing these particles.
Structure of soft and hard protein corona around polystyrene nanoplastics—Particle size and protein types
Researchers characterized the protein corona that forms around polystyrene nanoplastics of different sizes, finding that particle size influences which proteins bind and how tightly, with implications for nanoplastic toxicity and biological uptake.
Eco-Corona Formation on Photooxidized Plastics Exposed to Mixed Organic Matter
Researchers studied eco-corona formation on photooxidized plastic surfaces exposed to mixed organic matter, finding that weathering alters plastic surface chemistry in ways that significantly change how organic molecules adsorb and form corona layers.
A comparative study of microplastics under the influence of soil-typical eco-coronas through laboratory and field incubation experiments
Researchers compared the formation and properties of soil-typical eco-coronas on microplastics through both laboratory incubation and real-world field experiments, examining how natural organic matter coatings of proteins, carbohydrates, and humic acids alter microplastic surface hydrophobicity and transport behaviour. The study found that eco-corona composition significantly influences how microplastics move through terrestrial environments and interact with soil organisms.
A different protein corona cloaks “true-to-life” nanoplastics with respect to synthetic polystyrene nanobeads
Researchers found that environmentally realistic 'true-to-life' nanoplastics acquire a distinct protein corona compared to synthetic polystyrene nanobeads, suggesting that laboratory studies using standard nanobeads may not accurately reflect how environmental nanoplastics interact with biological systems.
ProteinMicroplasticCoronation Complexes TriggerProteome Changes in Brain-Derived Neuronal and Glial Cells
Researchers used mass spectrometry-based proteomics to compare how intact polystyrene microplastics versus protein-coated (coronated) microplastics affect brain-derived neuronal and glial cells. Protein corona formation on microplastics notably altered cellular protein expression compared to uncoated particles, with impacts on DNA repair, oxidative stress response, and membrane trafficking pathways.
Understanding the formation and influence of soil-typical eco-coronas on microplastics through laboratory and field incubation experiments
Researchers conducted laboratory and field incubation experiments to characterize eco-corona formation on microplastics in soil, finding that soil-derived organic matter including humic acids, proteins, and carbohydrates forms a coating that alters MP surface properties, transport behavior, and adsorption efficiency in terrestrial environments.
Environmental dimensions of the protein corona
Researchers reviewed how nanomaterials entering natural environments acquire an "eco-corona" — a coating of proteins and other biomolecules that alters how organisms recognize and interact with the particles — and called for targeted research into how this coating changes during food chain transfer and affects ecotoxicity.
Assessment on interactive prospectives of nanoplastics with plasma proteins and the toxicological impacts of virgin, coronated and environmentally released-nanoplastics
Researchers found that nanoplastics quickly coat themselves in blood proteins, forming a multi-layered "corona" that changes the proteins' shape and makes them biologically harmful; these protein-coated nanoplastics caused more DNA and cell damage in human blood cells than bare nanoplastics. The study highlights the need to regulate nanoplastics in medical products and better understand how they accumulate in the body.